Amtrak operates a train from New York to Coxsackie every 2 hours. Tickets cost $30 - $70 and the journey takes 1 h 59 min. VIA Rail also services this route every 3 hours. Alternatively, Trailways New York operates a bus from New York to Coxsackie hourly. Tickets cost $21 - $35 and the journey takes 2 h 5 min. Greyhound USA also services this route 4 times a day.
From New York Penn Station train to Hudson Amtrak then taxi to Coxsackie. 2 h 24 min $99. From New York, NY bus to Kingston, NY, 0313-0403 to Catskill, NY - P & R, then taxi to Coxsackie. 3 h 53 min $91. From New York drive to Coxsackie. 2 h 26 min $16.