There are 9 ways to get from New Smyrna Beach to Florida Keys by taxi, plane, bus, bus (Greyhound), train, car, shuttle, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Orlando Sanford, fly, bus
best- Take the taxi from New Smyrna Beach to Orlando-Sanford-Airport-SFB
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)SFB - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
4h 51m$170–475Bus (Greyhound)
cheapest- Take the bus from New Smyrna Beach to Miami Airport StationGreyhound US0710s
- Take the bus from Miami Airport Station to Big Pine KeyGreyhound US0720s
13h 57m$69–123Bus via Fort Pierce South
- Take the bus from Edgewater to Fort Pierce
- Take the bus from Fort Pierce to Miami Airport
- Take the bus from Miami Airport Station to Big Pine Key
12h 43m$84–194Taxi, train, bus
- Take the taxi from New Smyrna Beach to Deland
- Take the train from Deland to Miami Amtrak Station
- Take the bus from Miami Airport Station to Big Pine Key
13h 55m$149–317Drive 387 mi
- Drive from New Smyrna Beach to Florida Keys387 mi
7h 6m$71–102Bus to Tampa, fly
- Take the bus from Daytona International Speedway to Village Inn, Tampa
- Fly from Tampa (TPA) to Key West International Airport (EYW)TPA - EYW
9h 46m$250–670Bus to Saint Petersburg–Clearwater International Airport, fly
- Take the bus from Daytona International Speedway to Clearwater - 49Th St N + Lake Blvd
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)PIE - EYW
11h 3m$177–469Bus, shuttle
- Take the bus from New Smyrna Beach to Miami Airport StationGreyhound US0710s
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine LabTo the Keys
13h 40m$179–263Bus #2
- Take the bus from Daytona Beach to Miami Airport StationFlixBus 2431
- Take the bus from Miami Airport Station to Big Pine KeyGreyhound US0720s
17h 8m$73–145
New Smyrna Beach to Florida Keys by bus and foot
Questions & Answers
The cheapest way to get from New Smyrna Beach to Florida Keys is to drive which costs $70 - $110 and takes 7h 6m.
The fastest way to get from New Smyrna Beach to Florida Keys is to taxi and fly and bus which takes 4h 51m and costs $170 - $480.
No, there is no direct bus from New Smyrna Beach to Florida Keys. However, there are services departing from US1 AND Washington Ob and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Swallowtail Village Trail, Transfer Plaza, Daytona Beach, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 17h 8m.
The distance between New Smyrna Beach and Florida Keys is 349 miles. The road distance is 389.2 miles.
The best way to get from New Smyrna Beach to Florida Keys without a car is to bus via Fort Pierce South which takes 12h 43m and costs $80 - $200.
It takes approximately 4h 51m to get from New Smyrna Beach to Florida Keys, including transfers.
New Smyrna Beach to Florida Keys bus services, operated by Flixbus USA, depart from Daytona Beach station.
New Smyrna Beach to Florida Keys bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between New Smyrna Beach to Florida Keys is 389 miles. It takes approximately 7h 6m to drive from New Smyrna Beach to Florida Keys.
There are 860+ hotels available in Florida Keys.
What companies run services between New Smyrna Beach, FL, USA and Florida Keys, FL, USA?
You can take a vehicle from New Smyrna Beach to Florida Keys via Edgewater, Fort Pierce, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 12h 43m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 17m
- When
- Thursday and Sunday
- Estimated price
- $50–320
Flights from Saint Petersburg–Clearwater International Airport to Key West International Airport
- Ave. Duration
- 1h 2m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $45–310
- Website
- flybreeze.com
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $110–500
- Website
- aa.com
Flights from Tampa to Key West International Airport via Miami
- Ave. Duration
- 3h 2m
- When
- Every day
- Estimated price
- $45–300
- Website
- spirit.com
Flights from Tampa to Key West International Airport via Fort Lauderdale
- Ave. Duration
- 3h 11m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $85–380
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Deland to Miami Amtrak Station
- Ave. Duration
- 7h 6m
- Frequency
- Twice daily
- Estimated price
- $40–170
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Edgewater to Fort Pierce
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from New Smyrna Beach to Miami Airport Station
- Ave. Duration
- 7h 45m
- Frequency
- Once daily
- Estimated price
- $35–65
- Website
- https://www.greyhound.com/
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Fort Pierce to Miami Airport
- Ave. Duration
- 2h 20m
- Frequency
- 3 times a day
- Estimated price
- $15–65
- Website
- https://www.redcoachusa.com
- Web
- $15–65
- Phone
- +1-727-545-2088
- Website
- escotbuslines.com
Bus from Daytona International Speedway to Village Inn, Tampa
- Ave. Duration
- 3h 21m
- Frequency
- On demand
- Estimated price
- $60
- Website
- https://escotbuslines.com/
Bus from Daytona International Speedway to Clearwater - 49Th St N + Lake Blvd
- Ave. Duration
- 4h 1m
- Frequency
- On demand
- Estimated price
- $60
- Website
- https://escotbuslines.com/
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Daytona Beach to Miami Airport Station
- Ave. Duration
- 6h 50m
- Frequency
- 5 times a week
- Estimated price
- $45–95
- Schedules at
- flixbus.com
- Ave. Duration
- 39 min
- Estimated price
- $60–90
Daytona Taxi
- Phone
- +1 386-255-5555
- Website
- daytonataxi.com
American Taxi
- Phone
- +1 386-255-0000
- Website
- facebook.com
Daytona Taxi
- Phone
- +1 386-255-5555
- Website
- daytonataxi.com
American Taxi
- Phone
- +1 386-255-0000
- Website
- facebook.com
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