There are 9 ways to get from New Port Richey to Knoxville by car, plane, taxi, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Orlando Sanford, fly to Mcghee Tyson Airport
best- Drive from New Port Richey to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane SFB - TYS
4h 39m$177–751Bus to Saint Petersburg–Clearwater International Airport, fly to Asheville Regional Airport, drive
cheapest- Take the bus from Huey Ave + Tarpon Ave to Largo Transit Center - Shelter - Abus
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Asheville Regional Airport (AVL)plane PIE - AVL
- Drive from Asheville-Airport-AVL to Knoxvillecar
7h 53m$84–392Taxi, train, bus via Farragut
- Take the taxi from New Port Richey to Tampataxi
- Take the train from Tampa to Kissimmee Amtrak Stationtrain
- Take the train from Kissimmee Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the bus from New York to Knoxvillebus Nyc
39h 3m$445–887Taxi, bus
- Take the taxi from New Port Richey to University of South Floridataxi
- Take the bus from University of South Florida to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to New York City Chinatownbus
- Take the bus from New York City to Knoxvillebus Ny
41h 48m$279–501Drive 629.3 mi
- Drive from New Port Richey to Knoxvillecar 629.3 mi
11h 12m$115–166Bus to Saint Petersburg–Clearwater International Airport, fly to Mcghee Tyson Airport
- Take the bus from Huey Ave + Tarpon Ave to Largo Transit Center - Shelter - Abus
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Mcghee Tyson Airport (TYS)plane PIE - TYS
6h 3m$162–728Bus to Tampa, fly to Mcghee Tyson Airport
- Take the bus from Universal Plaza to SR 56 & Silver Maple Pkwybus
- Fly from Tampa (TPA) to Mcghee Tyson Airport (TYS)plane TPA - TYS
6h 38m$344–714Taxi, train to Orlando, fly to Mcghee Tyson Airport
- Take the taxi from New Port Richey to Tampataxi
- Take the train from Tampa to Kissimmee Amtrak Stationtrain
- Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane MCO - TYS
6h 54m$381–660Taxi, train, bus
- Take the taxi from New Port Richey to Tampataxi
- Take the train from Tampa to Kissimmee Amtrak Stationtrain
- Take the train from Kissimmee Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the bus from New York City to Knoxvillebus Ny
39h 7m$385–792
Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from New Port Richey to Knoxville is to drive which costs $110 - $170 and takes 11h 12m.
The fastest way to get from New Port Richey to Knoxville is to drive and fly which takes 4h 39m and costs $170 - $750.
The distance between New Port Richey and Knoxville is 647 miles. The road distance is 632.9 miles.
The best way to get from New Port Richey to Knoxville without a car is to taxi and train and bus via Farragut which takes 39h 3m and costs $440 - $900.
It takes approximately 4h 39m to get from New Port Richey to Knoxville, including transfers.
Yes, the driving distance between New Port Richey to Knoxville is 633 miles. It takes approximately 11h 12m to drive from New Port Richey to Knoxville.
There are 214+ hotels available in Knoxville.
What companies run services between New Port Richey, FL, USA and Knoxville, TN, USA?
There is no direct connection from New Port Richey to Knoxville. However, you can drive to Orlando-Sanford-Airport-SFB airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take the taxi to Tampa, take the train to Kissimmee Amtrak Station, take the train to Ny Moynihan Train Hall At Penn Station, walk to 34 St-Herald Sq, take the subway to East Broadway, walk to New York, take the bus to Knoxville, then take the taxi to Knoxville.
- Website
- allegiantair.com
Flights from Orlando Sanford to Mcghee Tyson Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–650
Flights from Saint Petersburg–Clearwater International Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 41m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–650
Flights from Orlando to Mcghee Tyson Airport
- Ave. Duration
- 1h 55m
- When
- Monday and Friday
- Estimated price
- $85–550
Flights from Saint Petersburg–Clearwater International Airport to Asheville Regional Airport
- Ave. Duration
- 1h 36m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $55–350
- Website
- delta.com
Flights from Tampa to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $95–600
Flights from Orlando to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $85–550
- Website
- aa.com
Flights from Tampa to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $100–650
Flights from Orlando to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $95–550
- Website
- southwest.com
Flights from Tampa to Mcghee Tyson Airport
- Ave. Duration
- 1h 45m
- When
- Saturday
- Estimated price
- $95–600
Flights from Tampa to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 4h 20m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–650
Flights from Orlando to Mcghee Tyson Airport
- Ave. Duration
- 1h 55m
- When
- Monday, Thursday, and Friday
- Estimated price
- $85–550
Flights from Orlando to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 4h 15m
- When
- Monday
- Estimated price
- $100–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Tampa to Kissimmee Amtrak Station
- Ave. Duration
- 1h 18m
- Frequency
- Once daily
- Estimated price
- $11–26
- Website
- https://www.amtrak.com/home.html
Train from Kissimmee Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 22h 21m
- Frequency
- Once daily
- Estimated price
- $160–500
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- 3 times a week
- Estimated price
- $95–140
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from University of South Florida to Orlando Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 3 times a day
- Estimated price
- $14–21
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to New York City Chinatown
- Ave. Duration
- 21h 25m
- Frequency
- 5 times a week
- Estimated price
- $100–280
- Schedules at
- flixbus.com
- Phone
- +1 615-939-8887
- jpan12692@gmail.com
- Website
- nytnbus.com
Bus from New York City to Knoxville
- Ave. Duration
- 12h
- Frequency
- 3 times a week
- Estimated price
- $80–100
- Schedules at
- nytnbus.com
- Phone
- +1 727-540-1900
- ride@psta.net
- Website
- psta.net
Bus from Huey Ave + Tarpon Ave to Largo Transit Center - Shelter - A
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- $3
- Schedules at
- psta.net
- Adult
- $3
- Phone
- +1 727-834-3322
- info@gopasco.com
- Website
- pascocountyfl.net
Bus from Universal Plaza to SR 56 & Silver Maple Pkwy
- Ave. Duration
- 1h 7m
- Frequency
- Every 2 hours
- Estimated price
- $2
- Website
- https://www.pascocountyfl.net/services/gopasco/index.php
- Ave. Duration
- 48 min
- Estimated price
- $80–110
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide





