There are 10 ways to get from New Orleans to South Carolina by plane, car, bus or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly New Orleans to Greenville/Spartanburg  •  4 h 52 min

  1. Fly from New Orleans (MSY) to Greenville/Spartanburg (GSP) MSY - GSP

$201 - $502

Cheapest option

Bus Megabus  •  16 h 20 min

  1. Take the bus from New Orleans to Marta Civic Center Station - Nb
  2. Take the bus from Atlanta GA to Columbia, SC
  3. Take the bus from Columbia, SC to Florence, SC

$84 - $123

8 alternative options

Fly New Orleans to Columbia  •  4 h 58 min

  1. Fly from New Orleans (MSY) to Columbia (CAE) MSY - CAE

$195 - $947

Fly New Orleans to Charlotte  •  3 h 51 min

  1. Fly from New Orleans (MSY) to Charlotte (CLT) MSY - CLT

$236 - $467

Fly New Orleans to Charleston  •  6 h 3 min

  1. Fly from New Orleans (MSY) to Charleston (CHS) MSY - CHS

$173 - $920

Drive to Gulfport/Biloxi, fly to Charlotte  •  3 h 49 min

  1. Drive from New Orleans to Gulfport/Biloxi
  2. Fly from Gulfport/Biloxi (GPT) to Charlotte (CLT) GPT - CLT

$312 - $1,401

Bus to Baton Rouge, fly to Charlotte  •  5 h 32 min

  1. Take the bus from New Orleans, La to Baton Rouge, La
  2. Fly from Baton Rouge (BTR) to Charlotte (CLT) BTR - CLT

$248 - $625

Bus via Mobile, Al  •  14 h 45 min

  1. Take the bus from New Orleans, La to Mobile, Al
  2. Take the bus from Mobile, Al to Atlanta, Ga
  3. Take the bus from Atlanta, GA to Florence, SC

$93 - $198

Train  •  26 h 24 min

  1. Take the train from New Orleans Union Passenger Terminal to Greensboro Galyon Transportation Center
  2. Take the train from Greensboro Galyon Transportation Center to Selma-Smithfield Amtrak
  3. Take the train from Selma-Smithfield Amtrak to Florence Amtrak

$178 - $480

Drive  •  12 h 21 min

  1. Drive from New Orleans to Florence 758.1 miles

$70 - $110

Questions & Answers

No, there is no direct bus from New Orleans to South Carolina. However, there are services departing from New Orleans, La and arriving at Florence, SC via Mobile, Al, Peachtree St @ Alabama St and Atlanta, GA. The journey, including transfers, takes approximately 14 h 45 min.

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No, there is no direct train from New Orleans to South Carolina. However, there are services departing from New Orleans Union Passenger Terminal and arriving at Florence Amtrak via Greensboro Galyon Transportation Center and Selma-Smithfield Amtrak. The journey, including transfers, takes approximately 26 h 24 min.

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The distance between New Orleans and South Carolina is 625 miles. The road distance is 758.1 miles.

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The best way to get from New Orleans to South Carolina without a car is to bus which takes 14 h 45 min and costs .

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It takes approximately 4 h 52 min to get from New Orleans to South Carolina, including transfers.

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New Orleans to South Carolina bus services, operated by Greyhound USA, depart from New Orleans, La station.

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New Orleans to South Carolina train services, operated by Amtrak, depart from New Orleans Union Passenger Terminal station.

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The best way to get from New Orleans to South Carolina is to fly which takes 4 h 52 min and costs . Alternatively, you can bus, which costs and takes 14 h 45 min, you could also train, which costs and takes 26 h 24 min.

Mode details

There is no direct flight from New Orleans Airport to Greenville/Spartanburg Airport. The quickest flight takes 3 h 10 min and has one stopover.

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New Orleans to South Carolina bus services, operated by South Eastern Stages, arrive at Florence, SC station.

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Map of how to get from New Orleans to South Carolina.
Launch map view
  • Distance: 625.1 miles
  • Duration: 4 h 52 min

What companies run services between New Orleans, LA, USA and South Carolina, USA?

Southwest Airlines, Delta and two other airlines fly from New Orleans to Greenville hourly. Alternatively, you can take a bus from New Orleans to Florence via Mobile, Al, Atlanta, Ga, Peachtree St @ Alabama St, Peachtree St Sw @ Brotherton Transportation Mall, and Atlanta, GA in around 14 h 45 min.

Airlines
American Airlines
Website
aa.com
Flights from New Orleans to Greenville/Spartanburg via Charlotte
Ave. Duration
4 h 5 min
When
Every day
Estimated price
$190 - $650
Flights from New Orleans to Greenville/Spartanburg via Dallas/Ft.Worth
Ave. Duration
6 h 9 min
When
Every day
Estimated price
$190 - $650
Flights from New Orleans to Columbia via Charlotte
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$190 - $900
Flights from New Orleans to Columbia via Dallas/Ft.Worth
Ave. Duration
5 h 46 min
When
Every day
Estimated price
$240 - $1,000
Flights from New Orleans to Columbia via Reagan Washington
Ave. Duration
6 h 7 min
When
Every day
Estimated price
$240 - $1,000
Flights from New Orleans to Columbia via Philadelphia
Ave. Duration
5 h 45 min
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
$260 - $1,100
Flights from New Orleans to Charlotte
Ave. Duration
2 h
When
Every day
Estimated price
$290 - $900
Flights from New Orleans to Charleston via Charlotte
Ave. Duration
4 h 29 min
When
Every day
Estimated price
$190 - $900
Flights from New Orleans to Charleston via Miami
Ave. Duration
4 h 35 min
When
Every day
Estimated price
$220 - $950
Flights from New Orleans to Charleston via Reagan Washington
Ave. Duration
5 h 26 min
When
Monday to Saturday
Estimated price
$240 - $1,000
Flights from New Orleans to Charleston via Dallas/Ft.Worth
Ave. Duration
5 h 28 min
When
Every day
Estimated price
$240 - $1,000
Flights from Gulfport/Biloxi to Charlotte
Ave. Duration
1 h 59 min
When
Every day
Estimated price
$390 - $2,700
Flights from Baton Rouge to Charlotte
Ave. Duration
2 h 7 min
When
Every day
Estimated price
$290 - $600
Flights from Baton Rouge to Charlotte via Dallas/Ft.Worth
Ave. Duration
4 h 58 min
When
Every day
Estimated price
$290 - $600
Delta
Website
delta.com
Flights from New Orleans to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 44 min
When
Every day
Estimated price
$170 - $650
Flights from New Orleans to Greenville/Spartanburg via Detroit
Ave. Duration
5 h 31 min
When
Saturday
Estimated price
$170 - $650
Flights from New Orleans to Columbia via Atlanta
Ave. Duration
4 h 2 min
When
Every day
Estimated price
$170 - $900
Flights from New Orleans to Charlotte via Atlanta
Ave. Duration
3 h 48 min
When
Every day
Estimated price
$180 - $900
Flights from New Orleans to Charleston via Atlanta
Ave. Duration
4 h 14 min
When
Every day
Estimated price
$170 - $900
Flights from Gulfport/Biloxi to Charlotte via Atlanta
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$410 - $2,700
Flights from Baton Rouge to Charlotte via Atlanta
Ave. Duration
4 h 1 min
When
Every day
Estimated price
$300 - $650
Southwest Airlines
Website
southwest.com
Flights from New Orleans to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$160 - $700
Flights from New Orleans to Charlotte via Nashville
Ave. Duration
3 h 40 min
When
Sunday
Estimated price
$360 - $750
Flights from New Orleans to Charleston via Nashville
Ave. Duration
3 h 50 min
When
Monday to Friday
Estimated price
$220 - $900
Flights from New Orleans to Charleston via Houston Hobby Apt
Ave. Duration
4 h 51 min
When
Every day
Estimated price
$250 - $1,000
Flights from New Orleans to Charleston via Dallas
Ave. Duration
4 h 40 min
When
Saturday
Estimated price
$270 - $1,000
Flights from New Orleans to Charleston via Chicago Midway
Ave. Duration
5 h 15 min
When
Saturday
Estimated price
$280 - $1,100
United Airlines
Website
united.com
Flights from New Orleans to Greenville/Spartanburg via Houston
Ave. Duration
4 h 28 min
When
Every day
Estimated price
$230 - $700
Flights from New Orleans to Greenville/Spartanburg via Washington Dulles
Ave. Duration
5 h 12 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $700
Flights from New Orleans to Columbia via Washington Dulles
Ave. Duration
5 h 23 min
When
Every day
Estimated price
$240 - $1,100
Flights from New Orleans to Columbia via Houston
Ave. Duration
5 h 24 min
When
Every day
Estimated price
$230 - $1,100
Flights from New Orleans to Columbia via Chicago O'Hare
Ave. Duration
5 h 49 min
When
Every day
Estimated price
$250 - $1,100
Flights from New Orleans to Charleston via Houston
Ave. Duration
4 h 52 min
When
Every day
Estimated price
$230 - $1,100
Flights from Baton Rouge to Charlotte via Houston
Ave. Duration
4 h 58 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$140 - $700
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from New Orleans Union Passenger Terminal to Greensboro Galyon Transportation Center
Ave. Duration
19 h 37 min
Frequency
Once daily
Estimated price
$110 - $340
Website
amtrak.com
Coach Seat
$110 - $180
Flexi Coach Seat
$210 - $300
Business Coach Seat
$240 - $340
Room
$470 - $650
Train from Greensboro Galyon Transportation Center to Selma-Smithfield Amtrak
Ave. Duration
2 h 22 min
Frequency
Once daily
Estimated price
$30 - $70
Website
amtrak.com
Coach Seat
$30 - $45
Flexi Coach Seat
$55 - $80
Business Coach Seat
$45 - $70
Room
$160 - $230
Train from Selma-Smithfield Amtrak to Florence Amtrak
Ave. Duration
2 h 25 min
Frequency
Once daily
Estimated price
$30 - $75
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $85
Business Coach Seat
$50 - $75
Room
$170 - $240
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from New Orleans, La to Baton Rouge, La
Ave. Duration
1 h 45 min
Frequency
Every 10 minutes
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from New Orleans, La to Mobile, Al
Ave. Duration
2 h 20 min
Frequency
Every 15 minutes
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $45
Bus from Mobile, Al to Atlanta, Ga
Ave. Duration
5 h 40 min
Frequency
Every 15 minutes
Estimated price
$35 - $90
Website
greyhound.com
Economy
$35 - $60
Flexible
$65 - $90
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Atlanta, GA to Florence, SC
Ave. Duration
5 h 30 min
Frequency
Once daily
Estimated price
$35 - $60
Schedules at
southeasternstages.com
Bus from Columbia, SC to Florence, SC
Ave. Duration
1 h 20 min
Frequency
Once daily
Estimated price
$19 - $30
Schedules at
southeasternstages.com
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from New Orleans to Marta Civic Center Station - Nb
Ave. Duration
8 h 45 min
Frequency
Twice daily
Estimated price
$40 - $60
Book at
megabus.com
Bus from Atlanta GA to Columbia, SC
Ave. Duration
4 h 15 min
Frequency
Twice daily
Estimated price
$21 - $35
Book at
megabus.com

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More Questions & Answers

South Carolina is 1 h ahead of New Orleans. It is currently 7:03 AM in New Orleans and 8:03 AM in South Carolina.

New Orleans to South Carolina train services, operated by Amtrak, arrive at Florence Amtrak station.

More details

Yes, the driving distance between New Orleans to South Carolina is 758 miles. It takes approximately 12 h 21 min to drive from New Orleans to South Carolina.

Get driving directions

United Airlines, Southwest Airlines, American Airlines and Delta offer flights from New Orleans Airport to Greenville/Spartanburg Airport.

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Book your New Orleans to South Carolina train tickets online with Rome2rio.

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There are 17+ hotels available in South Carolina. Prices start at $51 USD per night.

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The best way to get from New Orleans to New Orleans Airport is to bus which takes 25 min and costs .

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