There are 11 ways to get from New Orleans to South Carolina by plane, bus, car or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly New Orleans to Greenville/Spartanburg  •  4 h 57 min

  1. Fly from New Orleans (MSY) to Greenville/Spartanburg (GSP) MSY - GSP

$202 - $502

Cheapest option

Bus Megabus  •  18 h 24 min

  1. Take the bus from New Orleans to Marta Civic Center Station - Nb
  2. Take the bus from Atlanta, GA to Florence 0983 / ...

$82 - $126

9 alternative options

Fly New Orleans to Columbia  •  5 h 8 min

  1. Fly from New Orleans (MSY) to Columbia (CAE) MSY - CAE

$196 - $947

Fly New Orleans to Charlotte  •  3 h 59 min

  1. Fly from New Orleans (MSY) to Charlotte (CLT) MSY - CLT

$236 - $467

Fly New Orleans to Charleston  •  6 h

  1. Fly from New Orleans (MSY) to Charleston (CHS) MSY - CHS

$174 - $920

Bus to Baton Rouge, fly to Charlotte  •  5 h 34 min

  1. Take the bus from New Orleans, La to Baton Rouge, La
  2. Fly from Baton Rouge (BTR) to Charlotte (CLT) BTR - CLT

$248 - $625

Drive to Gulfport/Biloxi, fly to Charlotte  •  3 h 53 min

  1. Drive from New Orleans to Gulfport/Biloxi
  2. Fly from Gulfport/Biloxi (GPT) to Charlotte (CLT) GPT - CLT

$312 - $1,401

Bus via Savannah, Ga  •  19 h 12 min

  1. Take the bus from New Orleans, La to Mobile, Al
  2. Take the bus from Mobile, Al to Atlanta Arpt, Ga
  3. Take the bus from Atlanta Arpt, Ga to Savannah, Ga
  4. Take the bus from Savannah, Ga to Florence, Sc

$105 - $265

Train, bus  •  25 h 36 min

  1. Take the train from New Orleans Union Passenger Terminal Amtrak to Greensboro Galyon Transportation Center Amtrak
  2. Take the bus from Greensboro, Nc to Raleigh, Nc
  3. Take the bus from Raleigh, Nc to Florence, Sc

$152 - $420

Train  •  26 h 24 min

  1. Take the train from New Orleans Union Passenger Terminal Amtrak to Greensboro Galyon Transportation Center Amtrak
  2. Take the train from Greensboro Galyon Transportation Center Amtrak to Selma-Smithfield Amtrak
  3. Take the train from Selma-Smithfield Amtrak to Florence Amtrak

$178 - $480

Drive  •  12 h 21 min

  1. Drive from New Orleans to Florence 758.1 miles

$70 - $110

Questions & Answers

The cheapest way to get from New Orleans to South Carolina is to drive which costs $70 - $110 and takes 12 h 21 min.

More details

The quickest way to get from New Orleans to South Carolina is to drive and fly which costs $310 - $1,400 and takes 3 h 53 min.

More details

The distance between New Orleans and South Carolina is 625 miles. The road distance is 758.1 miles.

Get driving directions

It takes approximately 4 h 57 min to get from New Orleans to South Carolina, including transfers.

More details

No, there is no direct bus from New Orleans to South Carolina. However, there are services departing from New Orleans, La and arriving at Florence, Sc via Mobile, Al, Atlanta Arpt, Ga and Savannah, Ga. The journey, including transfers, takes approximately 19 h 12 min.

More details

No, there is no direct train from New Orleans to South Carolina. However, there are services departing from New Orleans Union Passenger Terminal Amtrak and arriving at Florence Amtrak via Greensboro Galyon Transportation Center Amtrak and Selma-Smithfield Amtrak. The journey, including transfers, takes approximately 26 h 24 min.

More details

What companies run services between New Orleans, LA, USA and South Carolina, USA?

Southwest Airlines, American Airlines and two other airlines fly from New Orleans to Greenville hourly. Alternatively, you can take a bus from New Orleans to Florence via Marta Civic Center Station - Nb, Civic Center Station, Garnett Station, and Atlanta, GA in around 18 h 24 min.

Airlines
American Airlines
Website
aa.com
Flights from New Orleans to Greenville/Spartanburg via Charlotte
Ave. Duration
4 h 28 min
When
Every day
Estimated price
$190 - $650
Flights from New Orleans to Greenville/Spartanburg via Dallas/Ft.Worth
Ave. Duration
4 h 59 min
When
Every day
Estimated price
$190 - $650
Flights from New Orleans to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
5 h 33 min
When
Every day
Estimated price
$190 - $650
Flights from New Orleans to Greenville/Spartanburg via Reagan Washington
Ave. Duration
5 h 59 min
When
Saturday
Estimated price
$190 - $650
Flights from New Orleans to Columbia via Charlotte
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$190 - $900
Flights from New Orleans to Columbia via Dallas/Ft.Worth
Ave. Duration
4 h 53 min
When
Every day
Estimated price
$240 - $1,000
Flights from New Orleans to Columbia via Reagan Washington
Ave. Duration
6 h 11 min
When
Every day
Estimated price
$240 - $1,000
Flights from New Orleans to Columbia via Philadelphia
Ave. Duration
5 h 59 min
When
Every day
Estimated price
$260 - $1,100
Flights from New Orleans to Charlotte
Ave. Duration
2 h 6 min
When
Every day
Estimated price
$290 - $900
Flights from New Orleans to Charleston via Charlotte
Ave. Duration
4 h 27 min
When
Every day
Estimated price
$190 - $900
Flights from New Orleans to Charleston via Miami
Ave. Duration
4 h 29 min
When
Every day
Estimated price
$220 - $950
Flights from New Orleans to Charleston via Reagan Washington
Ave. Duration
5 h 21 min
When
Monday to Saturday
Estimated price
$240 - $1,000
Flights from Baton Rouge to Charlotte
Ave. Duration
2 h 10 min
When
Every day
Estimated price
$290 - $600
Flights from Baton Rouge to Charlotte via Dallas/Ft.Worth
Ave. Duration
5 h 1 min
When
Every day
Estimated price
$290 - $600
Flights from Gulfport/Biloxi to Charlotte
Ave. Duration
2 h 3 min
When
Every day
Estimated price
$390 - $2,700
Delta
Website
delta.com
Flights from New Orleans to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h 19 min
When
Every day
Estimated price
$170 - $650
Flights from New Orleans to Greenville/Spartanburg via Detroit
Ave. Duration
6 h 4 min
When
Saturday
Estimated price
$170 - $650
Flights from New Orleans to Columbia via Atlanta
Ave. Duration
4 h 4 min
When
Every day
Estimated price
$170 - $900
Flights from New Orleans to Charlotte via Atlanta
Ave. Duration
4 h 14 min
When
Every day
Estimated price
$180 - $900
Flights from New Orleans to Charleston via Atlanta
Ave. Duration
4 h 9 min
When
Every day
Estimated price
$170 - $900
Flights from Baton Rouge to Charlotte via Atlanta
Ave. Duration
4 h 31 min
When
Every day
Estimated price
$300 - $650
Flights from Gulfport/Biloxi to Charlotte via Atlanta
Ave. Duration
4 h 23 min
When
Every day
Estimated price
$410 - $2,700
Southwest Airlines
Website
southwest.com
Flights from New Orleans to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h 22 min
When
Every day
Estimated price
$160 - $700
Flights from New Orleans to Charleston via Nashville
Ave. Duration
3 h 57 min
When
Saturday and Sunday
Estimated price
$220 - $900
Flights from New Orleans to Charleston via Houston Hobby Apt
Ave. Duration
4 h 50 min
When
Every day
Estimated price
$250 - $1,000
Flights from New Orleans to Charleston via St. Louis
Ave. Duration
4 h 45 min
When
Saturday
Estimated price
$260 - $1,000
Flights from New Orleans to Charleston via Baltimore
Ave. Duration
4 h 55 min
When
Sunday
Estimated price
$270 - $1,100
Flights from New Orleans to Charleston via Chicago Midway
Ave. Duration
5 h 15 min
When
Saturday
Estimated price
$280 - $1,100
United Airlines
Website
united.com
Flights from New Orleans to Greenville/Spartanburg via Houston
Ave. Duration
4 h 35 min
When
Saturday
Estimated price
$230 - $700
Flights from New Orleans to Greenville/Spartanburg via Washington Dulles
Ave. Duration
5 h 16 min
When
Every day
Estimated price
$230 - $700
Flights from New Orleans to Columbia via Houston
Ave. Duration
5 h 9 min
When
Every day
Estimated price
$230 - $1,100
Flights from New Orleans to Columbia via Washington Dulles
Ave. Duration
5 h 14 min
When
Every day
Estimated price
$240 - $1,100
Flights from New Orleans to Columbia via Chicago O'Hare
Ave. Duration
7 h 56 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $1,100
Flights from New Orleans to Charlotte via Houston
Ave. Duration
4 h 38 min
When
Every day
Estimated price
$220 - $750
Flights from New Orleans to Charleston via Houston
Ave. Duration
4 h 59 min
When
Every day
Estimated price
$230 - $1,100
Flights from Baton Rouge to Charlotte via Houston
Ave. Duration
4 h 38 min
When
Every day
Estimated price
$140 - $700
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from New Orleans Union Passenger Terminal Amtrak to Greensboro Galyon Transportation Center Amtrak
Ave. Duration
19 h 37 min
Frequency
Once daily
Estimated price
$110 - $340
Website
amtrak.com
Coach Seat
$110 - $180
Flexi Coach Seat
$210 - $300
Business Coach Seat
$240 - $340
Room
$470 - $650
Train from Greensboro Galyon Transportation Center Amtrak to Selma-Smithfield Amtrak
Ave. Duration
2 h 22 min
Frequency
Once daily
Estimated price
$30 - $70
Website
amtrak.com
Coach Seat
$30 - $45
Flexi Coach Seat
$55 - $80
Business Coach Seat
$45 - $70
Room
$160 - $230
Train from Selma-Smithfield Amtrak to Florence Amtrak
Ave. Duration
2 h 25 min
Frequency
Once daily
Estimated price
$30 - $75
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $85
Business Coach Seat
$50 - $75
Room
$170 - $240
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from New Orleans, La to Baton Rouge, La
Ave. Duration
1 h 45 min
Frequency
Every 10 minutes
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from New Orleans, La to Mobile, Al
Ave. Duration
2 h 20 min
Frequency
Every 15 minutes
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $45
Bus from Mobile, Al to Atlanta Arpt, Ga
Ave. Duration
7 h 10 min
Frequency
Every 2 hours
Estimated price
$35 - $95
Website
greyhound.com
Economy
$35 - $65
Flexible
$70 - $95
Bus from Atlanta Arpt, Ga to Savannah, Ga
Ave. Duration
4 h 20 min
Frequency
Every 30 minutes
Estimated price
$28 - $70
Website
greyhound.com
Economy
$28 - $45
Flexible
$50 - $70
Bus from Savannah, Ga to Florence, Sc
Ave. Duration
3 h 40 min
Frequency
Hourly
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from Greensboro, Nc to Raleigh, Nc
Ave. Duration
1 h 45 min
Frequency
Hourly
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from Raleigh, Nc to Florence, Sc
Ave. Duration
3 h 30 min
Frequency
Every 30 minutes
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from New Orleans to Marta Civic Center Station - Nb
Ave. Duration
8 h 45 min
Frequency
4 times a day
Estimated price
$35 - $60
Schedules at
us.megabus.com

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