There are 4 ways to get from New Orleans to Great Smoky Mountains National Park by plane, car or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from New Orleans, drive  •  6 h 22 min

  1. Fly from New Orleans (MSY) to Knoxville (TYS) MSY - TYS
  2. Drive from Knoxville to Great Smoky Mountains National Park

$206 - $626

Cheapest option

Bus, Megabus, drive  •  14 h 59 min

  1. Take the bus from New Orleans, La to Mobile, Al
  2. Take the bus from Mobile, Al to Atlanta, Ga
  3. Take the Megabus from Atlanta GA to Knoxville
  4. Drive from Knoxville to Great Smoky Mountains National Park

$86 - $182

2 alternative options

Drive to Gulfport/Biloxi, fly, drive  •  5 h 58 min

  1. Drive from New Orleans to Gulfport/Biloxi
  2. Fly from Gulfport/Biloxi (GPT) to Knoxville (TYS) GPT - TYS
  3. Drive from Knoxville to Great Smoky Mountains National Park

$282 - $1,520

Drive  •  10 h

  1. Drive from New Orleans to Great Smoky Mountains National Park 657.1 miles

$60 - $95

Questions & Answers

The cheapest way to get from New Orleans to Great Smoky Mountains National Park is to drive which costs $60 - $95 and takes 10 h.

More details

The quickest way to get from New Orleans to Great Smoky Mountains National Park is to drive and fly which costs $280 - $1,600 and takes 5 h 58 min.

More details

The distance between New Orleans and Great Smoky Mountains National Park is 549 miles. The road distance is 657.1 miles.

Get driving directions

It takes approximately 6 h 22 min to get from New Orleans to Great Smoky Mountains National Park, including transfers.

More details

What companies run services between New Orleans, LA, USA and Great Smoky Mountains National Park, TN, USA?

There is no direct connection from New Orleans to Great Smoky Mountains National Park. However, you can take the bus to New Orlns Arpt, take the walk to New Orleans airport, fly to Knoxville, then take the drive to Great Smoky Mountains National Park. Alternatively, you can take the drive to Gulfport/Biloxi airport, fly to Knoxville, then take the drive to Great Smoky Mountains National Park.

Airlines
Delta
Website
delta.com
Flights from New Orleans to Knoxville via Atlanta
Ave. Duration
3 h 49 min
When
Every day
Estimated price
$400 - $1,200
Flights from New Orleans to Knoxville via Detroit
Ave. Duration
5 h 31 min
When
Saturday
Estimated price
$400 - $1,200
Flights from Gulfport/Biloxi to Knoxville via Atlanta
Ave. Duration
3 h 38 min
When
Every day
Estimated price
$270 - $1,500
American Airlines
Website
aa.com
Flights from New Orleans to Knoxville via Charlotte
Ave. Duration
4 h 28 min
When
Every day
Estimated price
$450 - $1,200
Flights from New Orleans to Knoxville via Dallas/Ft.Worth
Ave. Duration
5 h 12 min
When
Every day
Estimated price
$450 - $1,200
Flights from New Orleans to Knoxville via Chicago O'Hare
Ave. Duration
5 h 2 min
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$450 - $1,200
Flights from New Orleans to Knoxville via Reagan Washington
Ave. Duration
5 h 16 min
When
Every day
Estimated price
$450 - $1,200
Flights from Gulfport/Biloxi to Knoxville via Charlotte
Ave. Duration
4 h 2 min
When
Every day
Estimated price
$330 - $1,600
Flights from Gulfport/Biloxi to Knoxville via Dallas/Ft.Worth
Ave. Duration
5 h 19 min
When
Every day
Estimated price
$400 - $1,700
United Airlines
Website
united.com
Flights from New Orleans to Knoxville via Houston
Ave. Duration
4 h 54 min
When
Every day
Estimated price
$410 - $1,200
Flights from New Orleans to Knoxville via Washington Dulles
Ave. Duration
5 h 15 min
When
Every day
Estimated price
$410 - $1,200
Flights from New Orleans to Knoxville via Chicago O'Hare
Ave. Duration
5 h 43 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$410 - $1,200
Flights from Gulfport/Biloxi to Knoxville via Houston
Ave. Duration
5 h 35 min
When
Every day
Estimated price
$390 - $1,800
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from New Orleans, La to Mobile, Al
Ave. Duration
2 h 20 min
Frequency
Every 15 minutes
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $45
Bus from Mobile, Al to Atlanta, Ga
Ave. Duration
5 h 40 min
Frequency
Every 30 minutes
Estimated price
$35 - $90
Website
greyhound.com
Economy
$35 - $60
Flexible
$65 - $90

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Trips to Great Smoky Mountains National Park