How to get fromNegotino to Istanbulby train, bus, car, shuttle or plane

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There are 11 ways to get from Negotino to Istanbul by train, bus, car, shuttle, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Train, bus
best
1. Take the train from Negotino to Gevgelija
2. Take the bus from Gevgelija to Thessaloníki
3. Take the bus from Thessaloniki Monastiriou Bus Stop to Istanbul Esenler Otogari
12h 13m
Train, bus to Pristina, fly to Istanbul Sabiha Gökçen International Airport
cheapest
1. Take the train from Negotino to Skopje, Transporten Centar
2. Take the bus from Skopje, Transporten Centar to Pristina
3. Fly from Pristina (PRN) to Istanbul Sabiha Gökçen International Airport (SAW)PRN - SAW
11h 18m
₺2,873–22,535
Bus, train
1. Take the bus from Kavadarci to Sofiya, Avtogara Serdika
2. Take the train from Sofia to Halkalı
20h 35m
Drive 715.6 km
1. Drive from Negotino to Istanbul715.6 km
7h 30m
₺4,592–6,632
Train, shuttle to Skopje International Airport, fly to Istanbul Sabiha Gökçen International Airport, Metro
1. Take the train from Negotino to Skopje, Transporten Centar
2. Take a shuttle bus from Skopje, Transporten Centar to Skopje, International Airport
3. Fly from Skopje International Airport (SKP) to Istanbul Sabiha Gökçen International Airport (SAW)SKP - SAW
4. Take the train from Sabiha Gokcen Airport to Ayrılık Çeşmesi
9h 34m
Bus via Thessaloníki
1. Take the bus from Negotino to Gevgelija
2. Take the bus from Gevgelija to Thessaloníki
3. Take the bus from Thessaloniki Simeonidis Tours Office to Istanbul Büyük Otogari
13h 18m
Bus
1. Take the bus from Negotino to Skopje, Transporten Centar
2. Take the bus from Skopje, Transporten Centar to Istanbul
15h 4m
Train, bus to Thessaloniki Airport Makedonia, fly to Istanbul, bus
1. Take the train from Negotino to Gevgelija
2. Take the bus from Gevgelija to Thessaloníki
3. Fly from Thessaloniki Airport Makedonia (SKG) to Istanbul (IST)SKG - IST
4. Take the bus from Istanbul Airport Bus to Istanbul Otogari
8h 55m
Train to Skopje International Airport, fly to Istanbul, bus
1. Take the train from Negotino to Skopje, Transporten Centar
2. Fly from Skopje International Airport (SKP) to Istanbul (IST)SKP - IST
3. Take the bus from Istanbul Airport Bus to Istanbul Otogari
10h 5m
₺4,246–14,067
Train, bus to Pristina, fly to Istanbul, bus
1. Take the train from Negotino to Skopje, Transporten Centar
2. Take the bus from Skopje, Transporten Centar to Pristina
3. Fly from Pristina (PRN) to Istanbul (IST)PRN - IST
4. Take the bus from Istanbul Airport Bus to Istanbul Otogari
11h 54m
₺3,690–15,734
Train, bus to Sofia Airport, fly to Istanbul, bus
1. Take the train from Negotino to Skopje, Transporten Centar
2. Take the bus from Skopje, Transporten Centar to Sofia
3. Fly from Sofia Airport (SOF) to Istanbul (IST)SOF - IST
4. Take the bus from Istanbul Airport Bus to Istanbul Otogari
13h 40m
₺4,575–12,819

Skopje International Airport (SKP) to Istanbul Sabiha Gökçen International Airport (SAW) flights

25Weekly Planes

1h 52mAverage Duration

₺1,842Cheapest Price

Questions & Answers

Map of how to get from Negotino to Istanbul.

Launch map view

Distance: 817.6 km
Duration: 12h 13m

What companies run services between Negotino, North Macedonia and Istanbul, Turkey?

You can take a bus from Negotino to Istanbul Büyük Otogari via Gevgelija, Thessaloníki, and Thessaloniki Simeonidis Tours Office in around 13h 18m.

Transport is disrupted due to the Russia-Ukraine war. Read more

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Istanbul(opens in a new window), Türkiye(opens in a new window)

The Turkish city is a traveller’s dream. A visit to the world-famous Blue Mosque is a must, along with Topkapi Palace and church-turned-mosque-turned-museum Hagia Sophia. Transport yourself to ancient times in the Grand Bazaar, walk through the fascinating Basilica Cistern, wander down Istiklal Avenue in the heart of the city, and take a river cruise down the Bosphorus. Rejuvenate your body at a local hammam or Turkish bath, sip on some divine Turkish coffee and feast on delicious food and baklava, before checking out the city’s thriving nightlife scene.

Things to do in Istanbul

Topkapı Palace(Opens in a new window)

The Topkapı Palace (Turkish: Topkapı Sarayı or in Ottoman Turkish: طوپقپو سرايى, Ṭopḳapu Sarāyı), or the Seraglio, is a large museum in Istanbul, Turkey. In the 15th century, it served as the main residence and administrative headquarters of the Ottoman sultans.

Hagia Sophia(Opens in a new window)

Hagia Sophia was a Greek Orthodox Christian patriarchal basilica (church), later an imperial mosque, and is now a museum (Ayasofya Müzesi) in Istanbul, Turkey. The Roman Empire's first Christian Cathedral, from the date of its construction in 537 AD, and until 1453, it served as an Eastern Orthodox cathedral and seat of the Patriarch of Constantinople, except between 1204 and 1261, when it was converted by the Fourth Crusaders to a Roman Catholic cathedral under the Latin Empire. The building was later converted into an Ottoman mosque from 29 May 1453 until 1931. It was then secularized and opened as a museum on 1 February 1935. Famous in particular for its massive dome, it is considered the epitome of Byzantine architecture and is said to have "changed the history of architecture". It remained the world's largest cathedral for nearly a thousand years, until Seville Cathedral was completed in 1520.

Golden Horn(Opens in a new window)

The Golden Horn (Turkish: Altın Boynuz; Ancient Greek: Χρυσόκερας, Chrysókeras; Latin: Sinus Ceratinus), also known by its modern Turkish name as Haliç, is a major urban waterway and the primary inlet of the Bosphorus in Istanbul, Turkey.

New Mosque(Opens in a new window)

The Yeni Cami (pronounced Yeni jami), meaning New Mosque; originally named the Valide Sultan Mosque (Turkish: Valide Sultan Camii) and later New Valide Sultan Mosque (Turkish: Yeni Valide Sultan Camii) after its partial reconstruction and completion between 1660 and 1665; is an Ottoman imperial mosque located in the Eminönü quarter of Istanbul, Turkey. It is situated on the Golden Horn, at the southern end of the Galata Bridge, and is one of the famous architectural landmarks of Istanbul.

Places to stay in Istanbul

Merdan Hotel(Opens in a new window)

8.2Very Good

Şar Apartment Suites(Opens in a new window)

8.2Very Good

Yılsam Sultanahmet Hotel(Opens in a new window)

8.7Fabulous

Eurostar Old City Hotel & Spa(Opens in a new window)

8.3Very Good

Rome2Rio makes travelling from Negotino to Istanbul easy.

Rome2Rio is a door-to-door travel information and booking engine, helping you get to and from any location in the world. Find all the transport options for your trip from Negotino to Istanbul right here. Rome2Rio displays up to date schedules, route maps, journey times and estimated fares from relevant transport operators, ensuring you can make an informed decision about which option will suit you best. Rome2Rio also offers online bookings for selected operators, making reservations easy and straightforward.