There are 7 ways to get from Natick to Pittsburgh by train, plane, bus, train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Boston Logan Airport, fly, bus
best- Take the train from Natick Center to Back Baytrain
- Fly from Boston Logan Airport (BOS) to Pittsburgh International Airport (PIT)plane BOS - PIT
- Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus
5h 39mBus
cheapest- Take the bus from Boston to New Yorkbus Ppb 5774 / ...
- Take the bus from Port Authority Bus Terminal to Pittsburgh Greyhoundbus New York
15h 1m$92–159Train (Amtrak)
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain Northeast Regional
- Take the train from Ny Moynihan Train Hall At Penn Station to Pittsburgh Amtrak Stationtrain Pennsylvanian
15h 32m$293–1,129Drive 553.3 mi
- Drive from Natick to Pittsburghcar 553.3 mi
10h 5m$101–146Train to Theodore Francis Green State Airport, fly
- Take the train from Back Bay to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Pittsburgh International Airport (PIT)plane PVD - PIT
7h 32m$92–515Train, bus to Bradley International Airport, fly
- Take the train from Natick Center to Worcestertrain
- Take the bus from Worcester to Hartfordbus
- Fly from Bradley International Airport (BDL) to Pittsburgh International Airport (PIT)plane BDL - PIT
8h 1m$103–587Train, bus
- Take the train from Natick Center to Worcestertrain
- Take the bus from Worcester Union Station to Port Authority Bus Terminalbus
- Take the bus from Port Authority Bus Terminal to Pittsburgh Intermodal Stationbus
15h 9m$99–166
Natick to Pittsburgh by bus
Comparing Your Travel Options
The cheapest way to get from Natick to Pittsburgh is to bus which costs $90 - $160 and takes 15h 1m.
The fastest way to get from Natick to Pittsburgh is to train and fly which takes 7h 32m and costs $90 - $550.
No, there is no direct bus from Natick to Pittsburgh. However, there are services departing from Natick Center - South Ave @ Washington St and arriving at Pittsburgh Greyhound via Boston and Port Authority Bus Terminal. The journey, including transfers, takes approximately 15h 1m.
No, there is no direct train from Natick to Pittsburgh station. However, there are services departing from Natick Center and arriving at Pittsburgh Amtrak Station via Boston and Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 15h 32m.
The distance between Natick and Pittsburgh is 546 miles. The road distance is 556.5 miles.
The best way to get from Natick to Pittsburgh without a car is to bus which takes 15h 1m and costs $90 - $160.
It takes approximately 5h 39m to get from Natick to Pittsburgh, including transfers.
Natick to Pittsburgh bus services, operated by Peter Pan Bus Lines, depart from Boston station.
Natick to Pittsburgh train services, operated by Amtrak, depart from Boston station.
The best way to get from Natick to Pittsburgh is to bus which takes 15h 1m and costs $90 - $160. Alternatively, you can train, which costs $290 - $1,200 and takes 15h 32m.
What companies run services between Natick, MA, USA and Pittsburgh, PA, USA?
You can take a bus from Natick Center - South Ave @ Washington St to Pittsburgh Greyhound via South Station - Bus Terminal Gates 4-6, Boston, New York, and Port Authority Bus Terminal in around 15h 1m. Alternatively, you can take a train from Natick Center to Pittsburgh Amtrak Station via Back Bay, Boston, and Ny Moynihan Train Hall At Penn Station in around 15h 32m.
- Website
- aa.com
Flights from Boston Logan Airport to Pittsburgh International Airport via Philadelphia
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $85–490
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Reagan Washington
- Ave. Duration
- 3h 53m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- $85–550
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Philadelphia
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $80–490
Flights from Bradley International Airport to Pittsburgh International Airport via Philadelphia
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $80–480
- Website
- united.com
Flights from Boston Logan Airport to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 3h 51m
- When
- Monday, Thursday, and Friday
- Estimated price
- $85–500
Flights from Boston Logan Airport to Pittsburgh International Airport via Montreal
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $100–550
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $85–550
Flights from Bradley International Airport to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $80–490
- Website
- southwest.com
Flights from Boston Logan Airport to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 3h 40m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–500
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 4h 7m
- When
- Tuesday, Wednesday, Sunday, and Saturday
- Estimated price
- $85–500
Flights from Bradley International Airport to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 3h 35m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $80–490
- Website
- delta.com
Flights from Boston Logan Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $80–480
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Detroit
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $110–600
- Website
- jetblue.com
Flights from Boston Logan Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- $80–480
- Website
- flybreeze.com
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 46m
- When
- Thursday and Sunday
- Estimated price
- $180–1,200
Flights from Bradley International Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 40m
- When
- Monday and Friday
- Estimated price
- $85–550
- Website
- aircanada.com
Flights from Boston Logan Airport to Pittsburgh International Airport via Montreal
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $100–550
Train from Natick Center to Back Bay
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–9
Train from Back Bay to TF Green Airport
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Train from Natick Center to Worcester
- Ave. Duration
- 49 min
- Frequency
- Every 2 hours
- Estimated price
- $5–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $5–11
Train from Natick Center to Worcester
- Ave. Duration
- 49 min
- Frequency
- Every 2 hours
- Estimated price
- $5–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $5–11
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 57m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Pittsburgh Amtrak Station
- Ave. Duration
- 9h 13m
- Frequency
- Once daily
- Estimated price
- $240–370
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 44m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
- Phone
- +1 412-442-2000
- Website
- Pittsburgh Regional Transit
Bus from Pittsburgh International Airport to Seventh Ave + William Penn Pl
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Website
- Pittsburgh Regional Transit
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from Boston to New York
- Ave. Duration
- 4h 35m
- Frequency
- Hourly
- Estimated price
- $40–75
- Website
- Peter Pan
Bus from Worcester to Hartford
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $12–22
- Website
- Peter Pan
- Phone
- +1-877-462-6342
- questions@us.megabus.com
- Website
- Megabus
Bus from Port Authority Bus Terminal to Pittsburgh Greyhound
- Ave. Duration
- 7h 45m
- Frequency
- Once daily
- Estimated price
- $50–80
- Website
- Megabus
- Adult One-way
- $50–80
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Worcester Union Station to Port Authority Bus Terminal
- Ave. Duration
- 4h 40m
- Frequency
- Twice daily
- Estimated price
- $29–45
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Pittsburgh Intermodal Station
- Ave. Duration
- 7h 40m
- Frequency
- Every 4 hours
- Estimated price
- $65–110
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
Natick to Pittsburgh bus services, operated by Peter Pan Bus Lines, arrive at New York station.
Natick to Pittsburgh train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Natick to Pittsburgh is 557 miles. It takes approximately 10h 5m to drive from Natick to Pittsburgh.
There are 734+ hotels available in Pittsburgh.
















