There are 7 ways to get from Natick to Pittsburgh by train, plane, bus, bus (Greyhound), train (Amtrak), car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Boston Logan Airport, fly, bus
best- Take the train from Natick Center to South Stationtrain
- Fly from Boston Logan Airport (BOS) to Pittsburgh International Airport (PIT)plane BOS - PIT
- Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus
5h 48mTrain to Worcester Regional Airport, fly
cheapest- Take the train from Natick Center to Worcestertrain
- Fly from Worcester Regional Airport (ORH) to Pittsburgh International Airport (PIT)plane ORH - PIT
11h 9m$66–393Bus
- Take the bus from Newton, MA to Manhattan, NYbus Cambridge
- Take the bus from Port Authority Bus Terminal to Pittsburgh Intermodal Stationbus Greyhound US0410 / ...
14h 24m$80–190Train (Amtrak)
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain Northeast Regional
- Take the train from Ny Moynihan Train Hall At Penn Station to Pittsburgh Amtrak Stationtrain Pennsylvanian
15h 39m$108–1,139Drive 553.3 mi
- Drive from Natick to Pittsburghcar 553.3 mi
10h 4m$101–146Train, train to Theodore Francis Green State Airport, fly, bus
- Take the train from Natick Center to Back Baytrain
- Take the train from Boston to Providencetrain
- Fly from Theodore Francis Green State Airport (PVD) to Pittsburgh International Airport (PIT)plane PVD - PIT
- Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus
6h 51mBus via South Station (Flixbus)
- Take the bus from Boston to New York Midtownbus FlixBus 2610 / ...
- Take the bus from New York Midtown to Pittsburgh Intermodal Stationbus FlixBus N2640 / ...
15h 45m$83–209
Natick to Pittsburgh by train (Amtrak)
Questions & Answers
The cheapest way to get from Natick to Pittsburgh is to drive which costs $100 - $150 and takes 10h 4m.
The fastest way to get from Natick to Pittsburgh is to drive which takes 10h 4m and costs $100 - $150.
No, there is no direct train from Natick to Pittsburgh station. However, there are services departing from Natick Center and arriving at Pittsburgh Amtrak Station via Boston and Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 15h 39m.
The distance between Natick and Pittsburgh is 547 miles. The road distance is 556.5 miles.
The best way to get from Natick to Pittsburgh without a car is to bus which takes 14h 24m and costs $80 - $190.
It takes approximately 5h 48m to get from Natick to Pittsburgh, including transfers.
Natick to Pittsburgh train services, operated by Amtrak Northeast Regional, depart from Boston station.
The best way to get from Natick to Pittsburgh is to bus which takes 14h 24m and costs $80 - $190. Alternatively, you can train, which costs $100 - $1,200 and takes 15h 39m.
Natick to Pittsburgh train services, operated by Amtrak Northeast Regional, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Natick to Pittsburgh is 557 miles. It takes approximately 10h 4m to drive from Natick to Pittsburgh.
What companies run services between Natick, MA, USA and Pittsburgh, PA, USA?
You can take a bus from Mathworks Apple Hill RT9 to Pittsburgh Intermodal Station via Woodland MBTA Train Station, Woodland, Riverside, Newton, MA, Manhattan, NY, and Port Authority Bus Terminal in around 14h 24m. Alternatively, you can take a train from Natick Center to Pittsburgh Amtrak Station via Back Bay, Boston, and Ny Moynihan Train Hall At Penn Station in around 15h 39m.
- Website
- aa.com
Flights from Boston Logan Airport to Pittsburgh International Airport via Philadelphia
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $65–390
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Reagan Washington
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $55–330
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Philadelphia
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $50–320
Flights from Worcester Regional Airport to Pittsburgh International Airport via Philadelphia
- Ave. Duration
- 7h 13m
- When
- Every day
- Estimated price
- $65–380
- Website
- delta.com
Flights from Boston Logan Airport to Pittsburgh International Airport
- Ave. Duration
- 2h 4m
- When
- Every day
- Estimated price
- $60–380
Flights from Boston Logan Airport to Pittsburgh International Airport via New York La Guardia
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $65–380
Flights from Worcester Regional Airport to Pittsburgh International Airport via New York La Guardia
- Ave. Duration
- 6h 44m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $60–380
- Website
- united.com
Flights from Boston Logan Airport to Pittsburgh International Airport via Newark
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $65–380
Flights from Boston Logan Airport to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $70–400
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Washington Dulles
- Ave. Duration
- 4h 13m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $55–320
- Website
- southwest.com
Flights from Boston Logan Airport to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 4h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $65–400
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport via Baltimore
- Ave. Duration
- 4h 5m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $55–320
Flights from Worcester Regional Airport to Pittsburgh International Airport via Orlando
- Ave. Duration
- 7h 15m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $150–700
- Website
- jetblue.com
Flights from Boston Logan Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $60–380
- Website
- flybreeze.com
Flights from Theodore Francis Green State Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 46m
- When
- Thursday and Sunday
- Estimated price
- $160–440
- Website
- spirit.com
Flights from Worcester Regional Airport to Pittsburgh International Airport via Fort Lauderdale
- Ave. Duration
- 7h 9m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $170–750
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from Natick Center to South Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- https://www.mbta.com
- Adult
- $3–9
Train from Natick Center to Back Bay
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- https://www.mbta.com
- Adult
- $3–9
Train from Boston to Providence
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- $5–14
- Website
- https://www.mbta.com
- Adult
- $5–14
Train from Natick Center to Worcester
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- https://www.mbta.com
- Adult
- $4–11
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 57m
- Frequency
- Every 3 hours
- Estimated price
- $30–300
- Website
- https://www.amtrak.com/home
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $30–300
- Business Class
- $95–360
Train from Boston to Providence
- Ave. Duration
- 34 min
- Frequency
- Every 3 hours
- Estimated price
- $5–210
- Website
- https://www.amtrak.com/home
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $5–210
- Business Class
- $45–240
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 36m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $50–490
- First Class
- $200–750
Train from Boston to Providence
- Ave. Duration
- 29 min
- Frequency
- Every 4 hours
- Estimated price
- $9–600
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $9–440
- First Class
- $100–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to Pittsburgh Amtrak Station
- Ave. Duration
- 9h 23m
- Frequency
- Once daily
- Estimated price
- $75–380
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 412-442-2000
- Website
- rideprt.org
Bus from Pittsburgh International Airport to Seventh Ave + William Penn Pl
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Website
- https://www.rideprt.org
- Phone
- 1 855-888-7160
- reservations@gobuses.com
- Website
- gobuses.com
Bus from Newton, MA to Manhattan, NY
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- $26–45
- Website
- https://www.gobuses.com
- Passenger
- $26–45
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Port Authority Bus Terminal to Pittsburgh Intermodal Station
- Ave. Duration
- 7h 40m
- Frequency
- Every 4 hours
- Estimated price
- $50–140
- Website
- https://www.greyhound.com/
- Phone
- +1-877-462-6342
- questions@us.megabus.com
- Website
- us.megabus.com
Bus from Port Authority Bus Terminal to Pittsburgh Intermodal Station
- Ave. Duration
- 7h 45m
- Frequency
- Once daily
- Website
- https://us.megabus.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Boston to New York Midtown
- Ave. Duration
- 4h 20m
- Frequency
- Every 2 hours
- Estimated price
- $30–60
- Schedules at
- flixbus.com
Bus from New York Midtown to Pittsburgh Intermodal Station
- Ave. Duration
- 8h 40m
- Frequency
- Twice daily
- Estimated price
- $50–140
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 590+ hotels available in Pittsburgh.
















