There are 5 ways to get from Natick to Keene by bus (Greyhound), train, bus, car, or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Framingham to Springfield Union Stationbus Greyhound US0270s
- Take the bus from Springfield Union Station to Keenebus Greyhound US0255s
5h 43m$23–51Drive 74.1 mi
cheapest- Drive from Natick to Keenecar 74.1 mi
1h 56m$14–20Train, bus
- Take the train from Framingham Amtrak to Springfieldtrain Lake Shore Limited
- Take the bus from Springfield Union Station to Keenebus Greyhound US0255s
5h 59m$36–84Train, bus via Worcester
- Take the train from Natick Center to Worcestertrain
- Take the bus from Worcester Union Station to Northamptonbus
- Take the bus from Northampton to Keenebus
5h 49m$23–45Train (Amtrak)
- Take the train from Framingham Amtrak to Springfieldtrain Lake Shore Limited
- Take the train from Springfield to Bellows Falls Amtrak Stationtrain Vermonter
7h 45m$54–123
Natick to Keene by train and bus (Greyhound)
Questions & Answers
The cheapest way to get from Natick to Keene is to drive which costs $13 - $20 and takes 1h 56m.
The fastest way to get from Natick to Keene is to drive which takes 1h 56m and costs $13 - $20.
No, there is no direct bus from Natick to Keene. However, there are services departing from Framingham and arriving at Keene via Springfield Union Station. The journey, including transfers, takes approximately 5h 43m.
No, there is no direct train from Natick to Keene station. However, there are services departing from Natick Center and arriving at Bellows Falls Amtrak Station via Framingham Amtrak and Springfield. The journey, including transfers, takes approximately 7h 45m.
The distance between Natick and Keene is 157 miles. The road distance is 74.5 miles.
The best way to get from Natick to Keene without a car is to bus which takes 5h 43m and costs $22 - $55.
It takes approximately 5h 43m to get from Natick to Keene, including transfers.
Natick to Keene bus services, operated by Greyhound USA, depart from Framingham station.
Natick to Keene train services, operated by Amtrak, depart from Framingham Amtrak station.
The best way to get from Natick to Keene is to bus which takes 5h 43m and costs $22 - $55. Alternatively, you can train, which costs $50 - $130 and takes 7h 45m.
What companies run services between Natick, MA, USA and Keene, NH, USA?
You can take a train from Natick Center to Keene via Framingham, Framingham, and Springfield Union Station in around 5h 43m. Alternatively, you can take a train from Natick Center to Keene via Framingham Amtrak, Springfield, Bellows Falls Amtrak Station, and Bellows Falls Bus Stop in around 7h 45m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Framingham Amtrak to Springfield
- Ave. Duration
- 1h 56m
- Frequency
- Once daily
- Estimated price
- $24–55
- Website
- Amtrak
Train from Framingham Amtrak to Springfield
- Ave. Duration
- 1h 56m
- Frequency
- Once daily
- Estimated price
- $24–55
- Website
- Amtrak
Train from Springfield to Bellows Falls Amtrak Station
- Ave. Duration
- 2h 11m
- Frequency
- Once daily
- Estimated price
- $26–55
- Website
- Amtrak
Train from Natick Center to Worcester
- Ave. Duration
- 49 min
- Frequency
- Every 2 hours
- Estimated price
- $5–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $5–11
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Framingham to Springfield Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $11–22
- Website
- Greyhound
Bus from Springfield Union Station to Keene
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $11–23
- Website
- Greyhound
Bus from Springfield Union Station to Keene
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $11–23
- Website
- Greyhound
Bus from Northampton to Keene
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $9–18
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Worcester Union Station to Northampton
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $9–16
- Schedules at
- Flixbus USA
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More Questions & Answers
Natick to Keene bus services, operated by Greyhound USA, arrive at Springfield Union Station.
Natick to Keene train services, operated by Amtrak, arrive at Springfield station.
Yes, the driving distance between Natick to Keene is 74 miles. It takes approximately 1h 56m to drive from Natick to Keene.
There are 43+ hotels available in Keene.











