There are 8 ways to get from Natick to Ithaca by bus (Flixbus), train, bus, car, plane, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Flixbus)
best- Take the bus from Boston to IthacaFlixBus 2691
9h 29m$63–149Fly to Ithaca Tompkins Regional Airport
cheapest- Fly from Boston Logan Airport (BOS) to Ithaca Tompkins Regional Airport (ITH)BOS - ITH
7h 52m$49–346Train, bus
- Take the train from Framingham Amtrak to Utica Amtrak StationLake Shore Limited
- Take the bus from Utica, NY to Ithaca, NYOurBus
12h 16m$52–186Drive 315.7 mi
- Drive from Natick to Ithaca315.7 mi
5h 54m$58–84Fly to Syracuse Hancock International Airport, bus
- Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)BOS - SYR
- Take the bus from Syracuse Airport, NY to Ithaca, NY
6h 23m$94–551Bus via Springfield
- Take the bus from Framingham to Springfield Union StationGreyhound US0270s
- Take the bus from Springfield Union Station to IthacaFlixBus 2691
9h 35m$63–226Fly to Rochester, bus
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)BOS - ROC
- Take the bus from Rochester, NY to Ithaca, NY
7h 26m$184–536Fly to Buffalo Niagara International Airport, bus
- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)BOS - BUF
- Take the bus from Buffalo Niagara International Airport to Ithaca
8h 19m$184–1,046
Natick to Ithaca by train and bus (Flixbus)
Questions & Answers
The cheapest way to get from Natick to Ithaca is to drive which costs $55 - $85 and takes 5h 54m.
The fastest way to get from Natick to Ithaca is to drive which takes 5h 54m and costs $55 - $85.
The distance between Natick and Ithaca is 401 miles. The road distance is 317.5 miles.
The best way to get from Natick to Ithaca without a car is to bus which takes 9h 29m and costs $60 - $150.
It takes approximately 9h 29m to get from Natick to Ithaca, including transfers.
The best way to get from Natick to Ithaca is to bus which takes 9h 29m and costs $60 - $150. Alternatively, you can fly, which costs $45 - $350 and takes 7h 52m.
Yes, the driving distance between Natick to Ithaca is 318 miles. It takes approximately 5h 54m to drive from Natick to Ithaca.
There are 59+ hotels available in Ithaca.
What companies run services between Natick, MA, USA and Ithaca, NY, USA?
Flixbus USA operates a bus from Boston to Ithaca once daily. Tickets cost $60–140 and the journey takes 7h 44m. Alternatively, United Airlines, Delta, and two other airlines fly from Boston Logan Airport (BOS) to Ithaca Tompkins Regional Airport (ITH) 5 times a day.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Boston Logan Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $70–460
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $65–410
Flights from Boston Logan Airport to Rochester via Philadelphia
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Saturday, and Sunday
- Estimated price
- $80–460
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $150–950
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 3h 46m
- When
- Monday, Tuesday, Friday, and Saturday
- Estimated price
- $160–1,000
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $180–1,100
- Website
- jetblue.com
Flights from Boston Logan Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $70–460
Flights from Boston Logan Airport to Rochester via New York JFK
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $70–440
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $150–950
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York JFK
- Ave. Duration
- 3h 44m
- When
- Monday, Tuesday, and Sunday
- Estimated price
- $170–1,000
- Website
- delta.com
Flights from Boston Logan Airport to Ithaca Tompkins Regional Airport via New York JFK
- Ave. Duration
- 5h 33m
- When
- Every day
- Estimated price
- $45–310
Flights from Boston Logan Airport to Rochester via New York La Guardia
- Ave. Duration
- 3h 59m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–440
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–1,000
- Website
- united.com
Flights from Boston Logan Airport to Ithaca Tompkins Regional Airport via Washington Dulles
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $65–360
Flights from Boston Logan Airport to Rochester via Newark
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $70–440
Flights from Boston Logan Airport to Rochester via Washington Dulles
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $90–500
- Website
- southwest.com
Flights from Boston Logan Airport to Rochester via Baltimore
- Ave. Duration
- 4h 2m
- When
- Monday to Wednesday
- Estimated price
- $85–490
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $190–1,100
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Framingham Amtrak to Utica Amtrak Station
- Ave. Duration
- 7h 20m
- Frequency
- Once daily
- Estimated price
- $30–120
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $30–70
- Coach Seat short notice purchase
- $35–120
- Business - advance purchase
- $45–220
- Business Class
- $80–280
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Boston to Ithaca
- Ave. Duration
- 7h 44m
- Frequency
- Once daily
- Estimated price
- $60–140
- Schedules at
- flixbus.com
Bus from Springfield Union Station to Ithaca
- Ave. Duration
- 5h 44m
- Frequency
- Once daily
- Estimated price
- $40–130
- Schedules at
- flixbus.com
Bus from Buffalo Niagara International Airport to Ithaca
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $30–60
- Schedules at
- flixbus.com
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Utica, NY to Ithaca, NY
- Ave. Duration
- 2h 45m
- Frequency
- Twice a week
- Estimated price
- $20–60
- Website
- https://www.ourbus.com
Bus from Syracuse Airport, NY to Ithaca, NY
- Ave. Duration
- 1h 45m
- Frequency
- 5 times a week
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
Bus from Rochester, NY to Ithaca, NY
- Ave. Duration
- 2h 30m
- Frequency
- 6 times a week
- Estimated price
- $20–60
- Website
- https://www.ourbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Framingham to Springfield Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $21–90
- Website
- https://www.greyhound.com/
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