There are 10 ways to get from Natick to Ithaca by bus (Flixbus), train, bus, car, plane, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Flixbus)
best- Take the bus from Boston to Ithacabus FlixBus 2691
9h 29m$47–89Train, bus
- Take the train from Framingham Amtrak to Utica Amtrak Stationtrain Lake Shore Limited
- Take the bus from Utica Bus Stop to Ithacabus FlixBus 2691
11h 39m$85–201Drive 315.7 mi
- Drive from Natick to Ithacacar 315.7 mi
5h 55m$58–84Fly to Ithaca Tompkins Regional Airport
- Fly from Boston Logan Airport (BOS) to Ithaca Tompkins Regional Airport (ITH)plane BOS - ITH
7h 25m$50–336Bus via Albany
- Take the bus from Framingham to Albany Bus Terminal, NYbus Greyhound US0270s
- Take the bus from Albany Bus Terminal, NY to Ithacabus FlixBus 2691
10h 9m$54–111Train, bus via Stamford
- Take the train from Boston to Stamford Amtrak Stationtrain Northeast Regional
- Take the bus from Stamford, CT - Tresser Blvd & Elm Street to Ithaca, NY - West Ave across from Bakers Flagpolebus New Haven
10h 11m$106–902Fly to Rochester, bus
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane BOS - ROC
- Take the bus from Rochester to Ithacabus
6h 50m$274–865Train, fly to Syracuse Hancock International Airport, bus
- Take the train from Natick Center to South Stationtrain
- Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane BOS - SYR
- Take the bus from Syracuse Bus Station to Ithacabus
6h 54m$86–627Fly to Buffalo Niagara International Airport, bus
- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane BOS - BUF
- Take the bus from Buffalo Niagara International Airport to Ithacabus
8h 13m$154–971Fly to Laguardia Airport, bus
- Fly from Boston Logan Airport (BOS) to Laguardia Airport (LGA)plane BOS - LGA
- Take the bus from New York to Ithacabus
9h 47m$193–669
Natick to Ithaca by bus (Flixbus)
Questions & Answers
The cheapest way to get from Natick to Ithaca is to bus which costs $45 - $90 and takes 9h 29m.
The fastest way to get from Natick to Ithaca is to drive which takes 5h 55m and costs $55 - $85.
No, there is no direct bus from Natick to Ithaca. However, there are services departing from Natick Center - South Ave @ Washington St and arriving at Ithaca via Boston. The journey, including transfers, takes approximately 9h 29m.
The distance between Natick and Ithaca is 399 miles. The road distance is 317.5 miles.
The best way to get from Natick to Ithaca without a car is to bus which takes 9h 29m and costs $45 - $90.
It takes approximately 9h 29m to get from Natick to Ithaca, including transfers.
Natick to Ithaca bus services, operated by Flixbus USA, depart from Boston station.
The best way to get from Natick to Ithaca is to bus which takes 9h 29m and costs $45 - $90. Alternatively, you can fly, which costs $50 - $340 and takes 7h 25m.
Natick to Ithaca bus services, operated by Flixbus USA, arrive at Ithaca station.
Yes, the driving distance between Natick to Ithaca is 318 miles. It takes approximately 5h 55m to drive from Natick to Ithaca.
What companies run services between Natick, MA, USA and Ithaca, NY, USA?
Flixbus USA operates a bus from Boston to Ithaca 5 times a week. Tickets cost $45–85 and the journey takes 7h 44m. Alternatively, Delta, United Airlines, and JetBlue Airways fly from Boston Logan Airport (BOS) to Ithaca Tompkins Regional Airport (ITH) every 4 hours.
- Website
- delta.com
Flights from Boston Logan Airport to Ithaca Tompkins Regional Airport via New York JFK
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $45–300
Flights from Boston Logan Airport to Rochester via Laguardia Airport
- Ave. Duration
- 3h 54m
- When
- Monday to Friday
- Estimated price
- $80–490
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Laguardia Airport
- Ave. Duration
- 4h 1m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–950
Flights from Boston Logan Airport to Laguardia Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $35–270
- Website
- aa.com
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $70–460
Flights from Boston Logan Airport to Rochester via Philadelphia
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $90–550
Flights from Boston Logan Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $70–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $130–900
Flights from Boston Logan Airport to Laguardia Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $35–270
- Website
- jetblue.com
Flights from Boston Logan Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $70–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $130–900
- Website
- united.com
Flights from Boston Logan Airport to Ithaca Tompkins Regional Airport via Washington Dulles
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $65–360
- Website
- southwest.com
Flights from Boston Logan Airport to Rochester via Baltimore
- Ave. Duration
- 4h 5m
- When
- Tuesday and Wednesday
- Estimated price
- $100–600
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 50m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $180–1,100
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Framingham Amtrak to Utica Amtrak Station
- Ave. Duration
- 7h 20m
- Frequency
- Once daily
- Estimated price
- $70–170
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Stamford Amtrak Station
- Ave. Duration
- 3h 7m
- Frequency
- Every 3 hours
- Estimated price
- $27–280
- Website
- https://www.amtrak.com/home
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $27–280
- Business Class
- $85–330
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Stamford Amtrak Station
- Ave. Duration
- 2h 44m
- Frequency
- Every 4 hours
- Estimated price
- $45–700
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $45–480
- First Class
- $180–700
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from Natick Center to South Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- https://www.mbta.com
- Adult
- $3–9
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Boston to Ithaca
- Ave. Duration
- 7h 44m
- Frequency
- 5 times a week
- Estimated price
- $45–85
- Schedules at
- flixbus.com
Bus from Utica Bus Stop to Ithaca
- Ave. Duration
- 2h 9m
- Frequency
- 5 times a week
- Estimated price
- $14–25
- Schedules at
- flixbus.com
Bus from Albany Bus Terminal, NY to Ithaca
- Ave. Duration
- 4h 4m
- Frequency
- 5 times a week
- Estimated price
- $27–50
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Ithaca
- Ave. Duration
- 1h 9m
- Frequency
- 5 times a week
- Estimated price
- $8–14
- Schedules at
- flixbus.com
Bus from Buffalo Niagara International Airport to Ithaca
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- $19–35
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Framingham to Albany Bus Terminal, NY
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $26–55
- Website
- https://www.greyhound.com/
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Stamford, CT - Tresser Blvd & Elm Street to Ithaca, NY - West Ave across from Bakers Flagpole
- Ave. Duration
- 4h 30m
- Frequency
- Once a week
- Estimated price
- $75–190
- Website
- https://www.ourbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Rochester to Ithaca
- Ave. Duration
- 1h 50m
- Frequency
- 3 times a day
- Estimated price
- $20–55
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $20–55
- Flexible
- $40–55
Bus from New York to Ithaca
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- $35–140
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $35–140
- Flexible
- $65–140
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