There are 7 ways to get from Natick to Hyannis by train, bus, car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus via Boston, South Station
best- Take the train from Natick Center to South Stationtrain Framingham/Worcester Line
- Take the bus from Boston South Buses to Hyannis Transportation Centerbus Hyannis - South Shore to Logan Airport
3h 18m$30–44Train
cheapest- Take the train from Natick Center to South Stationtrain Framingham/Worcester Line
- Take the train from South Station to Hyannistrain CapeFLYER
4h 16m$8–31Drive 80.2 mi
- Drive from Natick to Hyanniscar 80.2 mi
1h 42m$15–22Train, fly
- Take the train from Natick Center to Back Baytrain
- Fly from Boston Logan Airport (BOS) to Barnstable Municipal Airport (HYA)plane BOS - HYA
3h 3m$132–328Train, bus
- Take the train from Natick Center to South Stationtrain Framingham/Worcester Line
- Take the bus from Boston South Station to Hyannis Transportation Centerbus Boston
3h 21m$18–49Train, bus via Boston
- Take the train from Natick Center to South Stationtrain Framingham/Worcester Line
- Take the bus from Boston to Hyannisbus Bz 0956 / ...
3h 26m$18–49Bus
- Take the bus from Framingham to Bostonbus Greyhound US0270s
- Take the bus from Boston South Buses to Hyannis Transportation Centerbus Hyannis - South Shore to Logan Airport
4h 30m$31–48
Natick to Hyannis by train and bus
Questions & Answers
The cheapest way to get from Natick to Hyannis is to drive which costs $14 - $22 and takes 1h 42m.
The fastest way to get from Natick to Hyannis is to drive which takes 1h 42m and costs $14 - $22.
No, there is no direct bus from Natick to Hyannis. However, there are services departing from Framingham and arriving at Hyannis Transportation Center via Boston South Buses. The journey, including transfers, takes approximately 4h 30m.
No, there is no direct train from Natick to Hyannis. However, there are services departing from Natick Center and arriving at Hyannis via South Station. The journey, including transfers, takes approximately 4h 16m.
The distance between Natick and Hyannis is 91 miles. The road distance is 80.7 miles.
The best way to get from Natick to Hyannis without a car is to train and bus via Boston, South Station which takes 3h 18m and costs $30 - $45.
It takes approximately 3h 18m to get from Natick to Hyannis, including transfers.
Natick to Hyannis bus services, operated by Greyhound USA, depart from Framingham station.
Natick to Hyannis train services, operated by MBTA, depart from Natick Center station.
The best way to get from Natick to Hyannis is to train which takes 4h 16m and costs $8 - $35. Alternatively, you can bus, which costs $30 - $50 and takes 4h 30m.
What companies run services between Natick, MA, USA and Hyannis, MA, USA?
You can take a train from Natick Center to Hyannis via South Station in around 4h 16m. Alternatively, you can take a train from Natick Center to Hyannis Transportation Center via Framingham, Framingham, Boston, and Boston South Buses in around 4h 30m.
- Website
- capeair.com
Flights from Boston Logan Airport to Barnstable Municipal Airport
- Ave. Duration
- 47 min
- When
- Every day
- Estimated price
- $120–310
Flights from Boston Logan Airport to Barnstable Municipal Airport via Martha's Vineyard
- Ave. Duration
- 2h 9m
- When
- Friday and Saturday
- Estimated price
- $120–310
Flights from Boston Logan Airport to Barnstable Municipal Airport via Nantucket
- Ave. Duration
- 2h 17m
- When
- Saturday and Sunday
- Estimated price
- $120–310
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from Natick Center to South Station
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- https://www.mbta.com
- Website
- https://www.mbta.com/guides/world-cup-guide
- Adult
- $3–9
Train from Natick Center to South Station
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- https://www.mbta.com
- Website
- https://www.mbta.com/guides/world-cup-guide
- Adult
- $3–9
Train from Natick Center to Back Bay
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- https://www.mbta.com
- Website
- https://www.mbta.com/guides/world-cup-guide
- Adult
- $3–9
Train from Natick Center to South Station
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- https://www.mbta.com
- Website
- https://www.mbta.com/guides/world-cup-guide
- Adult
- $3–9
Train from Natick Center to South Station
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- https://www.mbta.com
- Website
- https://www.mbta.com/guides/world-cup-guide
- Adult
- $3–9
- Phone
- +1 508-775-8504
- info@capecodrta.org
- Website
- capeflyer.com
Train from South Station to Hyannis
- Ave. Duration
- 2h 30m
- Frequency
- 3 times a week
- Estimated price
- $5–22
- Website
- https://capeflyer.com
- South Station to Bourne
- $20
- South Station to Hyannis
- $22
- Middleborough to Hyannis
- $5
- Phone
- +1 (508) 746-0378
- info@p-b.com
- Website
- p-b.com
Bus from Boston South Buses to Hyannis Transportation Center
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $27–35
- Website
- https://www.p-b.com/
- One Way - Adult
- $27–35
Bus from Boston South Buses to Hyannis Transportation Center
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $27–35
- Website
- https://www.p-b.com/
- One Way - Adult
- $27–35
- Phone
- 1-800-343-9999
- Website
- peterpanbus.com
Bus from Boston South Station to Hyannis Transportation Center
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Estimated price
- $15–40
- Website
- https://peterpanbus.com
Bus from Boston to Hyannis
- Ave. Duration
- 1h 40m
- Frequency
- Every 3 hours
- Estimated price
- $15–40
- Website
- https://peterpanbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Framingham to Boston
- Ave. Duration
- 50 min
- Frequency
- Twice daily
- Estimated price
- $3–7
- Website
- https://www.greyhound.com/
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More Questions & Answers
Natick to Hyannis bus services, operated by Greyhound USA, arrive at Boston station.
Natick to Hyannis train services, operated by MBTA, arrive at South Station.
Yes, the driving distance between Natick to Hyannis is 81 miles. It takes approximately 1h 42m to drive from Natick to Hyannis.
There are 927+ hotels available in Hyannis.












