There are 4 ways to get from Natick to Hyannis by bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Natick Center - South Ave @ Washington St to South Station - Bus Terminal Gates 4-6bus Worcester Line Shuttle
- Take the bus from Boston South Buses to Hyannis Transportation Centerbus Hyannis - South Shore to Logan Airport
3h 16m$29–39Drive 80.2 mi
cheapest- Drive from Natick to Hyanniscar 80.2 mi
1h 42m$15–22Train, fly
- Take the train from Natick Center to Back Baytrain
- Fly from Boston Logan Airport (BOS) to Barnstable Municipal Airport (HYA)plane BOS - HYA
3h 8m$142–328Train, bus
- Take the train from Natick Center to South Stationtrain Framingham/Worcester Line
- Take the bus from Boston to Hyannisbus Bz 0956 / ...
3h 26m$17–34
Natick to Hyannis by bus
Comparing Your Travel Options
The cheapest way to get from Natick to Hyannis is to drive which costs $14 - $22 and takes 1h 42m.
The fastest way to get from Natick to Hyannis is to drive which takes 1h 42m and costs $14 - $22.
No, there is no direct bus from Natick to Hyannis. However, there are services departing from Natick Center - South Ave @ Washington St and arriving at Hyannis Transportation Center via Boston South Buses. The journey, including transfers, takes approximately 3h 16m.
The distance between Natick and Hyannis is 91 miles. The road distance is 80.7 miles.
The best way to get from Natick to Hyannis without a car is to bus which takes 3h 16m and costs $28 - $40.
It takes approximately 3h 16m to get from Natick to Hyannis, including transfers.
Natick to Hyannis bus services, operated by MBTA, depart from Natick Center - South Ave @ Washington St station.
Natick to Hyannis bus services, operated by MBTA, arrive at South Station - Bus Terminal Gates 4-6.
Yes, the driving distance between Natick to Hyannis is 81 miles. It takes approximately 1h 42m to drive from Natick to Hyannis.
There are 871+ hotels available in Hyannis.
What companies run services between Natick, MA, USA and Hyannis, MA, USA?
You can take a bus from Natick Center - South Ave @ Washington St to Hyannis Transportation Center via Boston South Buses in around 3h 16m.
- Website
- capeair.com
Flights from Boston Logan Airport to Barnstable Municipal Airport
- Ave. Duration
- 45 min
- When
- Every day
- Estimated price
- $130–310
Flights from Boston Logan Airport to Barnstable Municipal Airport via Nantucket
- Ave. Duration
- 2h 24m
- When
- Saturday and Sunday
- Estimated price
- $130–310
Train from Natick Center to Back Bay
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–9
Train from Natick Center to South Station
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–9
Bus from Natick Center - South Ave @ Washington St to South Station - Bus Terminal Gates 4-6
- Ave. Duration
- 44 min
- Frequency
- 3 times a day
- Estimated price
- $1–5
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Phone
- +1 (508) 746-0378
- info@p-b.com
- Website
- Plymouth & Brockton
Bus from Boston South Buses to Hyannis Transportation Center
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $27–35
- Website
- Plymouth & Brockton
- One Way - Adult
- $27–35
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from Boston to Hyannis
- Ave. Duration
- 1h 40m
- Frequency
- Every 3 hours
- Estimated price
- $14–25
- Website
- Peter Pan
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