There are 4 ways to get from Natick to Ayer by train, bus (Greyhound), car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Natick Center to Back Baytrain Framingham/Worcester Line
- Take the train from North Station to Ayertrain Fitchburg Line
2h 53m$12–25Drive 27.7 mi
cheapest- Drive from Natick to Ayercar 27.7 mi
42 min$6–8Bus (Greyhound)
- Take the bus from Framingham to Bostonbus Greyhound US0270s
- Take the bus from Boston to Ayer MAbus Greyhound US0256S
4h 32m$12–20Taxi
- Take the taxi from Natick to Ayertaxi 27.7 mi
42 min$85–110
Natick to Ayer by train and subway
Comparing Your Travel Options
The cheapest way to get from Natick to Ayer is to drive which costs $5 - $8 and takes 42 min.
The fastest way to get from Natick to Ayer is to drive which takes 42 min and costs $5 - $8.
No, there is no direct bus from Natick to Ayer. However, there are services departing from Natick Center MBTA and arriving at Ayer MA via Framingham and Boston. The journey, including transfers, takes approximately 4h 32m.
No, there is no direct train from Natick to Ayer. However, there are services departing from Natick Center and arriving at Ayer via Back Bay and North Station. The journey, including transfers, takes approximately 2h 53m.
The distance between Natick and Ayer is 55 miles. The road distance is 27.8 miles.
The best way to get from Natick to Ayer without a car is to train which takes 2h 53m and costs $12 - $25.
It takes approximately 2h 53m to get from Natick to Ayer, including transfers.
Natick to Ayer bus services, operated by Greyhound USA, depart from Framingham station.
Natick to Ayer train services, operated by MBTA, depart from Natick Center station.
The best way to get from Natick to Ayer is to train which takes 2h 53m and costs $12 - $25. Alternatively, you can bus, which costs $11 - $20 and takes 4h 32m.
What companies run services between Natick, MA, USA and Ayer, MA, USA?
You can take a train from Natick Center to Ayer via Back Bay, Back Bay, North Station, and North Station in around 2h 53m. Alternatively, you can take a bus from Natick Center MBTA to Ayer MA via Framingham MBTA Station, Framingham, and Boston in around 4h 32m.
Train from Natick Center to Back Bay
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–9
Train from North Station to Ayer
- Ave. Duration
- 1h 3m
- Frequency
- Every 2 hours
- Estimated price
- $6–13
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $6–13
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Framingham to Boston
- Ave. Duration
- 50 min
- Frequency
- Once daily
- Estimated price
- $3–6
- Website
- Greyhound
Bus from Boston to Ayer MA
- Ave. Duration
- 1h 25m
- Frequency
- 5 times a week
- Estimated price
- $7–12
- Website
- Greyhound
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Related travel guides
Need to know: Greyhound
Read the travel guide
Booking & Getting There
Natick to Ayer bus services, operated by Greyhound USA, arrive at Boston station.
Natick to Ayer train services, operated by MBTA, arrive at Back Bay station.
Yes, the driving distance between Natick to Ayer is 28 miles. It takes approximately 42 min to drive from Natick to Ayer.
There are 62+ hotels available in Ayer.







