There are 10 ways to get from Natchez to Destin by car, train, bus, taxi, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive, train, bus, taxi
best- Drive from Natchez to Brookhaven Stationcar
- Take the train from Brookhaven Station to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans, LA - Union Passenger Terminal to Gulfport, MStrain
- Take the bus from Gulfport to Crestviewbus
- Take the taxi from Crestview to Destintaxi
12h 13m$200–312Drive 337.7 mi
cheapest- Drive from Natchez to Destincar 337.7 mi
6h 35m$62–89Drive, train, bus, taxi via Jackson
- Drive from Natchez to Brookhaven Stationcar
- Take the train from Brookhaven Station to Jacksontrain
- Take the bus from Jackson to New Orleans Bus Stationbus
- Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus
- Take the bus from Biloxi to Crestviewbus
- Take the taxi from Crestview to Destintaxi
15h 28m$203–320Fly Natchez to Pensacola International Airport, taxi
- Fly from Natchez (HEZ) to Pensacola International Airport (PNS)plane HEZ - PNS
- Take the taxi from Pensacola-Airport-PNS to Destintaxi
7h 39m$218–593Drive, train, bus, taxi via Pascagoula
- Drive from Natchez to McComb Stationcar
- Take the train from McComb Station to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans, LA - Union Passenger Terminal to Pascagoula, MStrain
- Take the bus from Pascagoula to Crestviewbus
- Take the taxi from Crestview to Destintaxi
12h 28m$199–313Drive, train, bus, taxi via Mobile
- Drive from Natchez to Brookhaven Stationcar
- Take the train from Brookhaven Station to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans, LA - Union Passenger Terminal to Mobile, ALtrain
- Take the bus from Mobile to Crestviewbus
- Take the taxi from Crestview to Destintaxi
13h 6m$202–347Fly Natchez to Northwest Florida Beaches International Airport, taxi
- Fly from Natchez (HEZ) to Northwest Florida Beaches International Airport (ECP)plane HEZ - ECP
- Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi
7h 43m$228–603Drive to Baton Rouge Metropolitan Airport, fly to Destin–Fort Walton Beach Airport
- Drive from Natchez to Baton-Rouge-Airport-BTRcar
- Fly from Baton Rouge Metropolitan Airport (BTR) to Destin–Fort Walton Beach Airport (VPS)plane BTR - VPS
6h 29m$125–467Taxi to Alexandria International Airport, fly to Destin–Fort Walton Beach Airport
- Take the taxi from Natchez to Alexandria International Airport (AEX)taxi
- Fly from Alexandria International Airport (AEX) to Destin–Fort Walton Beach Airport (VPS)plane AEX - VPS
6h 28m$137–481Drive, train to Jackson/Vicksburg, fly to Destin–Fort Walton Beach Airport
- Drive from Natchez to Brookhaven Stationcar
- Take the train from Brookhaven Station to Jacksontrain
- Fly from Jackson/Vicksburg (JAN) to Destin–Fort Walton Beach Airport (VPS)plane JAN - VPS
8h 9m$162–527
Natchez (HEZ) to Pensacola International Airport (PNS) flights
Questions & Answers
The cheapest way to get from Natchez to Destin is to drive which costs $60 - $90 and takes 6h 35m.
The fastest way to get from Natchez to Destin is to taxi and fly which takes 6h 28m and costs $130 - $490.
The distance between Natchez and Destin is 486 miles. The road distance is 339.7 miles.
It takes approximately 12h 13m to get from Natchez to Destin, including transfers.
Yes, the driving distance between Natchez to Destin is 340 miles. It takes approximately 6h 35m to drive from Natchez to Destin.
There are 6799+ hotels available in Destin.
What companies run services between Natchez, MS, USA and Destin, FL, USA?
There is no direct connection from Natchez to Destin. However, you can drive to Brookhaven Station, take the train to New Orleans Union Passenger Terminal, take the train to Gulfport, MS, walk to Gulfport, take the bus to Crestview, then take the taxi to Destin. Alternatively, you can drive to Brookhaven Station, take the train to Jackson, walk to Jackson, take the bus to New Orleans Bus Station, take the bus to Biloxi Transit Center, walk to Biloxi, take the bus to Crestview, then take the taxi to Destin.
- Website
- aa.com
Flights from Baton Rouge Metropolitan Airport to Destin–Fort Walton Beach Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $90–470
Flights from Baton Rouge Metropolitan Airport to Destin–Fort Walton Beach Airport via Charlotte
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $100–490
Flights from Alexandria International Airport to Destin–Fort Walton Beach Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $85–440
Flights from Jackson/Vicksburg to Destin–Fort Walton Beach Airport via Charlotte
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- $90–470
Flights from Jackson/Vicksburg to Destin–Fort Walton Beach Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $95–470
Flights from Jackson/Vicksburg to Destin–Fort Walton Beach Airport via Reagan Washington
- Ave. Duration
- 5h 52m
- When
- Sunday
- Estimated price
- $130–600
- Website
- delta.com
Flights from Baton Rouge Metropolitan Airport to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $70–390
Flights from Alexandria International Airport to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $75–400
Flights from Jackson/Vicksburg to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $60–370
- Website
- united.com
Flights from Natchez to Pensacola International Airport via Houston
- Ave. Duration
- 7h 10m
- When
- Every day
- Estimated price
- $70–400
Flights from Natchez to Northwest Florida Beaches International Airport via Houston
- Ave. Duration
- 7h 14m
- When
- Every day
- Estimated price
- $80–420
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Brookhaven Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 3h 31m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- https://www.amtrak.com/home.html
Train from New Orleans, LA - Union Passenger Terminal to Gulfport, MS
- Ave. Duration
- 1h 47m
- Frequency
- Twice daily
- Estimated price
- $18–40
- Website
- https://www.amtrak.com/home.html
Train from Brookhaven Station to Jackson
- Ave. Duration
- 1h 32m
- Frequency
- Once daily
- Estimated price
- $15–35
- Website
- https://www.amtrak.com/home.html
Train from McComb Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 3h 7m
- Frequency
- Once daily
- Estimated price
- $29–65
- Website
- https://www.amtrak.com/home.html
Train from New Orleans, LA - Union Passenger Terminal to Pascagoula, MS
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- $27–60
- Website
- https://www.amtrak.com/home.html
Train from New Orleans, LA - Union Passenger Terminal to Mobile, AL
- Ave. Duration
- 3h 43m
- Frequency
- Twice daily
- Estimated price
- $30–85
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Gulfport to Crestview
- Ave. Duration
- 2h 56m
- Frequency
- Once daily
- Estimated price
- $55–75
- Schedules at
- omnibusexpress.com
Bus from Biloxi to Crestview
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $55–75
- Schedules at
- omnibusexpress.com
Bus from Pascagoula to Crestview
- Ave. Duration
- 2h 23m
- Frequency
- Once daily
- Estimated price
- $50–70
- Schedules at
- omnibusexpress.com
Bus from Mobile to Crestview
- Ave. Duration
- 1h 43m
- Frequency
- Once daily
- Estimated price
- $45–65
- Schedules at
- omnibusexpress.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Jackson to New Orleans Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from New Orleans Bus Station to Biloxi Transit Center
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $14–28
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from New Orleans Bus Station to Biloxi Transit Center
- Ave. Duration
- 1h 25m
- Frequency
- 6 times a week
- Estimated price
- $11–20
- Schedules at
- flixbus.com
- Ave. Duration
- 1h 4m
- Estimated price
- $22–160
Choice Taxi
- Phone
- +1 850-529-1806
- Website
- mychoicetaxi.com
Able Shuttle and Taxi
- Phone
- +1 850-607-0209
Red Cabs of Panama City
- Phone
- +1 850-733-2227
- Website
- myfloridacabs.com
H2O Shuttle Taxi and Limo
- Phone
- +1 850-708-2870
Emerald Taxi
- Phone
- +1 850-792-2546
- Website
- emeraldtaxiandshuttle.com
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