Rome2Rio

How to get fromNatchez to DestinBy car, train, bus, taxi, or plane

Find Transport to Destin

See all options

There are 8 ways to get from Natchez to Destin by car, train, bus, taxi, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, train, bus, taxi

    best
    1. Drive from Natchez to McComb Stationcar car
    2. Take the train from McComb Station to New Orleans Union Passenger Terminaltrain train
    3. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus bus
    4. Take the bus from Biloxi to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    12h 7m
    $187–286

  2. Drive 337.7 mi

    cheapest
    1. Drive from Natchez to Destincar car 337.7 mi
    6h 35m
    $62–89

  3. Fly Natchez to Pensacola International Airport, taxi

    1. Fly from Natchez (HEZ) to Pensacola International Airport (PNS)plane plane HEZ - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    7h 39m
    $223–593

  4. Drive, train, bus, taxi via Jackson

    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Jacksontrain train
    3. Take the bus from Jackson to New Orleans Bus Stationbus bus
    4. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus bus
    5. Take the bus from Biloxi to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    15h 28m
    $202–320

  5. Drive to Baton Rouge Metropolitan Airport, fly to Destin–Fort Walton Beach Airport

    1. Drive from Natchez to Baton-Rouge-Airport-BTRcar car
    2. Fly from Baton Rouge Metropolitan Airport (BTR) to Destin–Fort Walton Beach Airport (VPS)plane plane BTR - VPS
    6h 29m
    $125–467

  6. Taxi to Alexandria International Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the taxi from Natchez to Alexandria International Airport (AEX)taxi taxi
    2. Fly from Alexandria International Airport (AEX) to Destin–Fort Walton Beach Airport (VPS)plane plane AEX - VPS
    6h 28m
    $137–491

  7. Taxi to Monroe Regional Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the taxi from Natchez to Monroe Regional Airport (MLU)taxi taxi
    2. Fly from Monroe Regional Airport (MLU) to Destin–Fort Walton Beach Airport (VPS)plane plane MLU - VPS
    6h 42m
    $132–471

  8. Fly Natchez to Northwest Florida Beaches International Airport, taxi

    1. Fly from Natchez (HEZ) to Northwest Florida Beaches International Airport (ECP)plane plane HEZ - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    9h 47m
    $228–603

Natchez (HEZ) to Pensacola International Airport (PNS) flights

Calendar14Weekly Planes
Duration7h 9mAverage Duration
Ticket$75Cheapest Price
See schedules

Questions & Answers

What companies run services between Natchez, MS, USA and Destin, FL, USA?

There is no direct connection from Natchez to Destin. However, you can drive to McComb Station, take the train to New Orleans Union Passenger Terminal, walk to New Orleans Bus Station, take the bus to Biloxi Transit Center, walk to Biloxi, take the bus to Crestview, then take the taxi to Destin. Alternatively, you can drive from Natchez to Destin in around 6h 35m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Natchez

Trips to Destin

Popular routes