There are 10 ways to get from Natchez to Destin by car, train, bus, taxi, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive, train, bus, taxi
best- Drive from Natchez to Brookhaven Stationcar
- Take the train from Brookhaven Station to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain
- Take the bus from Gulfport to Crestviewbus
- Take the taxi from Crestview to Destintaxi
10h 54m$208–322Drive 337.7 mi
cheapest- Drive from Natchez to Destincar 337.7 mi
6h 35m$62–89Drive, train, bus, taxi via Mobile
- Drive from Natchez to Brookhaven Stationcar
- Take the train from Brookhaven Station to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain
- Take the bus from Mobile to Crestviewbus
- Take the taxi from Crestview to Destintaxi
11h 34m$207–357Fly Natchez to Pensacola International Airport, taxi
- Fly from Natchez (HEZ) to Pensacola International Airport (PNS)plane HEZ - PNS
- Take the taxi from Pensacola-Airport-PNS to Destintaxi
7h 39m$218–563Drive, train, bus, taxi via Pascagoula
- Drive from Natchez to McComb Stationcar
- Take the train from McComb Station to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Pascagoulatrain
- Take the bus from Pascagoula to Crestviewbus
- Take the taxi from Crestview to Destintaxi
11h 11m$208–323Drive, train, bus, taxi via Jackson
- Drive from Natchez to Brookhaven Stationcar
- Take the train from Brookhaven Station to Jacksontrain
- Take the bus from Jackson to New Orleans Bus Stationbus
- Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus
- Take the bus from Biloxi to Crestviewbus
- Take the taxi from Crestview to Destintaxi
15h 10m$207–313Fly Natchez to Northwest Florida Beaches International Airport, taxi
- Fly from Natchez (HEZ) to Northwest Florida Beaches International Airport (ECP)plane HEZ - ECP
- Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi
7h 43m$248–623Drive to Baton Rouge Metropolitan Airport, fly to Destin–Fort Walton Beach Airport
- Drive from Natchez to Baton-Rouge-Airport-BTRcar
- Fly from Baton Rouge Metropolitan Airport (BTR) to Destin–Fort Walton Beach Airport (VPS)plane BTR - VPS
6h 42m$125–457Taxi to Alexandria International Airport, fly to Destin–Fort Walton Beach Airport
- Take the taxi from Natchez to Alexandria International Airport (AEX)taxi
- Fly from Alexandria International Airport (AEX) to Destin–Fort Walton Beach Airport (VPS)plane AEX - VPS
6h 34m$137–471Drive, train to Jackson/Vicksburg, fly to Destin–Fort Walton Beach Airport
- Drive from Natchez to Brookhaven Stationcar
- Take the train from Brookhaven Station to Jacksontrain
- Fly from Jackson/Vicksburg (JAN) to Destin–Fort Walton Beach Airport (VPS)plane JAN - VPS
7h 41m$169–517
Natchez (HEZ) to Pensacola International Airport (PNS) flights
Questions & Answers
The cheapest way to get from Natchez to Destin is to drive which costs $60 - $90 and takes 6h 35m.
The fastest way to get from Natchez to Destin is to taxi and fly which takes 6h 34m and costs $130 - $480.
The distance between Natchez and Destin is 486 miles. The road distance is 339.7 miles.
It takes approximately 10h 54m to get from Natchez to Destin, including transfers.
Yes, the driving distance between Natchez to Destin is 340 miles. It takes approximately 6h 35m to drive from Natchez to Destin.
There are 3825+ hotels available in Destin.
What companies run services between Natchez, MS, USA and Destin, FL, USA?
There is no direct connection from Natchez to Destin. However, you can drive to Brookhaven Station, take the train to New Orleans Union Passenger Terminal, take the train to Gulfport Amtrak Sta, walk to Gulfport, take the bus to Crestview, then take the taxi to Destin. Alternatively, you can drive to Brookhaven Station, take the train to New Orleans Union Passenger Terminal, take the train to Mobile Amtrak Sta, walk to Mobile, take the bus to Crestview, then take the taxi to Destin.
- Website
- aa.com
Flights from Baton Rouge Metropolitan Airport to Destin–Fort Walton Beach Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $95–450
Flights from Baton Rouge Metropolitan Airport to Destin–Fort Walton Beach Airport via Charlotte
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $100–470
Flights from Alexandria International Airport to Destin–Fort Walton Beach Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $90–430
Flights from Jackson/Vicksburg to Destin–Fort Walton Beach Airport via Charlotte
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $95–450
Flights from Jackson/Vicksburg to Destin–Fort Walton Beach Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $95–450
Flights from Jackson/Vicksburg to Destin–Fort Walton Beach Airport via Reagan Washington
- Ave. Duration
- 6h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–600
- Website
- delta.com
Flights from Baton Rouge Metropolitan Airport to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $70–380
Flights from Alexandria International Airport to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $75–390
Flights from Jackson/Vicksburg to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $65–360
- Website
- united.com
Flights from Natchez to Pensacola International Airport via Houston
- Ave. Duration
- 7h 10m
- When
- Every day
- Estimated price
- $70–370
Flights from Natchez to Northwest Florida Beaches International Airport via Houston
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $80–410
- Website
- southwest.com
Flights from Jackson/Vicksburg to Destin–Fort Walton Beach Airport via Houston Hobby Apt
- Ave. Duration
- 6h 30m
- When
- Saturday
- Estimated price
- $85–420
Flights from Jackson/Vicksburg to Destin–Fort Walton Beach Airport via Nashville
- Ave. Duration
- 7h 35m
- When
- Tuesday and Wednesday
- Estimated price
- $75–390
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Brookhaven Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Gulfport Amtrak Sta
- Ave. Duration
- 59 min
- Frequency
- Twice daily
- Estimated price
- $21–45
- Website
- https://www.amtrak.com/home.html
Train from Brookhaven Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Mobile Amtrak Sta
- Ave. Duration
- 2h 43m
- Frequency
- Twice daily
- Estimated price
- $30–90
- Website
- https://www.amtrak.com/home.html
Train from McComb Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $35–70
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Pascagoula
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
Train from Brookhaven Station to Jackson
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- https://www.amtrak.com/home.html
Train from Brookhaven Station to Jackson
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Gulfport to Crestview
- Ave. Duration
- 2h 56m
- Frequency
- Once daily
- Estimated price
- $55–75
- Schedules at
- omnibusexpress.com
Bus from Mobile to Crestview
- Ave. Duration
- 1h 43m
- Frequency
- Once daily
- Estimated price
- $45–65
- Schedules at
- omnibusexpress.com
Bus from Pascagoula to Crestview
- Ave. Duration
- 2h 23m
- Frequency
- Once daily
- Estimated price
- $50–70
- Schedules at
- omnibusexpress.com
Bus from Biloxi to Crestview
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $55–75
- Schedules at
- omnibusexpress.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Jackson to New Orleans Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Bus from New Orleans Bus Station to Biloxi Transit Center
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $13–26
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from New Orleans Bus Station to Biloxi Transit Center
- Ave. Duration
- 1h 25m
- Frequency
- 6 times a week
- Estimated price
- $13–22
- Schedules at
- flixbus.com
- Ave. Duration
- 1h 4m
- Estimated price
- $22–180
Able Shuttle and Taxi
- Phone
- +1 850-607-0209
Choice Taxi
- Phone
- +1 850-529-1806
- Website
- mychoicetaxi.com
Emerald Taxi
- Phone
- +1 850-792-2546
- Website
- emeraldtaxiandshuttle.com
H2O Shuttle Taxi and Limo
- Phone
- +1 850-708-2870
Red Cabs of Panama City
- Phone
- +1 850-733-2227
- Website
- myfloridacabs.com
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