There are 9 ways to get from Natchez to Des Moines by plane, car, train, bus, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Natchez
best- Fly from Natchez (HEZ) to Des Moines (DSM)plane HEZ - DSM
8h 38m$130–494Drive to Baton Rouge Metropolitan Airport, fly
cheapest- Drive from Natchez to Baton-Rouge-Airport-BTRcar
- Fly from Baton Rouge Metropolitan Airport (BTR) to Des Moines (DSM)plane BTR - DSM
6h 46m$112–473Drive, train, bus
- Drive from Natchez to Brookhaven Stationcar
- Take the train from Brookhaven Station to Jacksontrain
- Take the bus from Jackson to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Kansas Citybus
- Take the bus from Kansas City to Des Moinesbus
22h 11m$117–370Drive, train, bus via Chicago
- Drive from Natchez to Brookhaven Stationcar
- Take the train from Brookhaven Station to Chicago Union Stationtrain
- Take the bus from Chicago Bus Station to Des Moinesbus
26h 31m$247–527Drive 800.6 mi
- Drive from Natchez to Des Moinescar 800.6 mi
15h 52m$147–212Taxi to Alexandria International Airport, fly
- Take the taxi from Natchez to Alexandria International Airport (AEX)taxi
- Fly from Alexandria International Airport (AEX) to Des Moines (DSM)plane AEX - DSM
6h 36m$114–457Taxi to Monroe Regional Airport, fly
- Take the taxi from Natchez to Monroe Regional Airport (MLU)taxi
- Fly from Monroe Regional Airport (MLU) to Des Moines (DSM)plane MLU - DSM
6h 48m$114–457Taxi to Lafayette Regional Airport, fly
- Take the taxi from Natchez to Lafayette Regional Airport (LFT)taxi
- Fly from Lafayette Regional Airport (LFT) to Des Moines (DSM)plane LFT - DSM
7h 56m$119–477Drive, train, bus via Chicago #2
- Drive from Natchez to Brookhaven Stationcar
- Take the train from Brookhaven Station to Jacksontrain
- Take the bus from Jackson to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Des Moinesbus
25h 30m$169–380
Natchez (HEZ) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Natchez to Des Moines is to drive which costs $140 - $220 and takes 15h 52m.
The fastest way to get from Natchez to Des Moines is to taxi and fly which takes 6h 36m and costs $110 - $460.
The distance between Natchez and Des Moines is 718 miles. The road distance is 805.3 miles.
It takes approximately 8h 38m to get from Natchez to Des Moines, including transfers.
Yes, the driving distance between Natchez to Des Moines is 805 miles. It takes approximately 15h 52m to drive from Natchez to Des Moines.
There are 252+ hotels available in Des Moines.
What companies run services between Natchez, MS, USA and Des Moines, IA, USA?
United Airlines flies from Natchez (HEZ) to Des Moines (DSM) once daily.
- Website
- aa.com
Flights from Alexandria International Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $75–410
Flights from Baton Rouge Metropolitan Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $80–430
Flights from Baton Rouge Metropolitan Airport to Des Moines via Charlotte
- Ave. Duration
- 6h 17m
- When
- Every day
- Estimated price
- $110–550
Flights from Baton Rouge Metropolitan Airport to Des Moines via Reagan Washington
- Ave. Duration
- 7h 18m
- When
- Monday to Friday
- Estimated price
- $130–600
Flights from Monroe Regional Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $75–410
Flights from Lafayette Regional Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $80–430
Flights from Lafayette Regional Airport to Des Moines via Charlotte
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $110–550
- Website
- delta.com
Flights from Alexandria International Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–470
Flights from Baton Rouge Metropolitan Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $95–460
Flights from Monroe Regional Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 4m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–460
Flights from Lafayette Regional Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 4m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–470
- Website
- united.com
Flights from Natchez to Des Moines via Houston
- Ave. Duration
- 8h 10m
- When
- Every day
- Estimated price
- $85–440
Flights from Alexandria International Airport to Des Moines via Houston
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $80–430
Flights from Baton Rouge Metropolitan Airport to Des Moines via Houston
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $85–440
Flights from Lafayette Regional Airport to Des Moines via Houston
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $80–430
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Brookhaven Station to Jackson
- Ave. Duration
- 1h 32m
- Frequency
- Once daily
- Estimated price
- $12–28
- Website
- https://www.amtrak.com/home.html
Train from Brookhaven Station to Chicago Union Station
- Ave. Duration
- 17h 19m
- Frequency
- Once daily
- Estimated price
- $180–410
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Jackson to Memphis Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 34m
- Frequency
- 3 times a day
- Estimated price
- $55–100
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 30m
- Frequency
- Once daily
- Estimated price
- $85–170
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Memphis Bus Station to Kansas City
- Ave. Duration
- 9h 45m
- Frequency
- 4 times a week
- Estimated price
- $45–170
- Book at
- https://www.jeffersonlines.com
Bus from Kansas City to Des Moines
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Memphis Bus Station to Chicago Bus Station
- Ave. Duration
- 11h 5m
- Frequency
- 5 times a week
- Estimated price
- $60–110
- Schedules at
- flixbus.com
- Ave. Duration
- 2h 20m
- Estimated price
- $22–26
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