Southwest Airlines flies from Nashville to Columbus twice daily. Alternatively, Greyhound USA operates a bus from Nashville to Columbus once daily. Tickets cost $40 - $110 and the journey takes 8 h 46 min.
From Nashville, TN bus to Nashville airport, fly to Columbus airport, then bus to Columbus. 3 h 16 min $430. From Nashville, TN bus to Columbus, OH. 8 h 46 min $81. From Nashville, TN bus to Louisville, KY, bus to Cincinnati, OH, then bus to Columbus Ohio State University. 8 h 50 min $80. From Nashville drive to Columbus. 6 h 18 min $45.