There are 6 ways to get from Naples to Des Moines by plane, car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Naples Airport to Des Moines
best- Fly from Naples Airport (NAP) to Des Moines (DSM)NAP - DSM
14h 34m$568–2,066Fly Naples Airport to Mason City, bus
cheapest- Fly from Naples Airport (NAP) to Mason City (MCW)NAP - MCW
- Take the bus from Mason City to Des Moines
22h 15m$304–1,160Fly Naples Airport to Fort Dodge Municipal Airport, drive
- Fly from Naples Airport (NAP) to Fort Dodge Municipal Airport (FOD)NAP - FOD
- Drive from Fort Dodge Municipal Airport (FOD) to Des Moines
27h 10m$311–1,121Fly Naples Airport to Waterloo Municipal Airport, bus
- Fly from Naples Airport (NAP) to Waterloo Municipal Airport (ALO)NAP - ALO
- Take the bus from Waterloo to Des Moines
17h 56m$338–1,167Fly Naples Airport to The Eastern Iowa Airport, bus
- Fly from Naples Airport (NAP) to The Eastern Iowa Airport (CID)NAP - CID
- Take the bus from Iowa City to Des Moines
18h 45m$340–1,180Train to Fiumicino International Airport, fly to Des Moines
- Take the train from Napoli Centrale to Roma Termini
- Fly from Fiumicino International Airport (FCO) to Des Moines (DSM)FCO - DSM
17h 32m$547–2,083
Naples Airport (NAP) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Naples to Des Moines is to fly and drive which costs $310 - $1,200 and takes 27h 10m.
The fastest way to get from Naples to Des Moines is to fly which takes 14h 34m and costs $550 - $2,100.
The distance between Naples and Des Moines is 5215 miles.
It takes approximately 14h 34m to get from Naples to Des Moines, including transfers.
Des Moines is 7h behind Naples. It is currently 5:06 PM in Naples and 10:06 AM in Des Moines.
There are 236+ hotels available in Des Moines.
What companies run services between Naples, Italy and Des Moines, IA, USA?
Delta, American Airlines, and two other airlines fly from Naples Airport (NAP) to Des Moines (DSM) 6 times a week.
- Website
- united.com
Flights from Naples Airport to Fort Dodge Municipal Airport via Chicago O'Hare
- Ave. Duration
- 25h 29m
- When
- Every day
- Estimated price
- $290–1,100
Flights from Naples Airport to Fort Dodge Municipal Airport via Frankfurt, Chicago O'Hare
- Ave. Duration
- 26h 4m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $300–1,300
Flights from Naples Airport to Fort Dodge Municipal Airport via Fiumicino International Airport, Chicago O'Hare
- Ave. Duration
- 25h 15m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $440–1,200
Flights from Naples Airport to Fort Dodge Municipal Airport via Milan Malpensa, Chicago O'Hare
- Ave. Duration
- 28h 19m
- When
- Sunday
- Estimated price
- $290–1,100
Flights from Naples Airport to Mason City via Chicago O'Hare
- Ave. Duration
- 25h 23m
- When
- Every day
- Estimated price
- $290–1,100
Flights from Naples Airport to Mason City via Frankfurt, Chicago O'Hare
- Ave. Duration
- 26h 8m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $330–1,300
Flights from Naples Airport to Mason City via Fiumicino International Airport, Chicago O'Hare
- Ave. Duration
- 18h 45m
- When
- Tuesday to Sunday
- Estimated price
- $290–1,100
Flights from Naples Airport to Mason City via Paris Charles de Gaulle, Chicago O'Hare
- Ave. Duration
- 19h 5m
- When
- Every day
- Estimated price
- $290–1,100
Flights from Naples Airport to Mason City via Munich, Chicago O'Hare
- Ave. Duration
- 19h 20m
- When
- Monday, Friday, and Sunday
- Estimated price
- $290–1,200
Flights from Naples Airport to Mason City via Milan Malpensa, Chicago O'Hare
- Ave. Duration
- 28h 13m
- When
- Sunday
- Estimated price
- $290–1,100
Flights from Fiumicino International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 14h 18m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $500–2,100
- Website
- delta.com
Flights from Naples Airport to Des Moines via Atlanta
- Ave. Duration
- 14h 23m
- When
- Wednesday
- Estimated price
- $600–2,300
Flights from Naples Airport to The Eastern Iowa Airport via Atlanta
- Ave. Duration
- 19h 46m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $320–1,200
Flights from Fiumicino International Airport to Des Moines via Minneapolis
- Ave. Duration
- 13h 41m
- When
- Wednesday and Sunday
- Estimated price
- $500–2,000
Flights from Fiumicino International Airport to Des Moines via Detroit
- Ave. Duration
- 14h 43m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $500–2,000
Flights from Fiumicino International Airport to Des Moines via Atlanta
- Ave. Duration
- 16h 49m
- When
- Every day
- Estimated price
- $550–2,200
- Website
- aa.com
Flights from Naples Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 15h 30m
- When
- Monday, Thursday, and Sunday
- Estimated price
- $550–2,100
Flights from Naples Airport to Waterloo Municipal Airport via Chicago O'Hare
- Ave. Duration
- 14h 23m
- When
- Every day
- Estimated price
- $290–1,100
Flights from Naples Airport to The Eastern Iowa Airport via Chicago O'Hare
- Ave. Duration
- 14h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $280–1,100
Flights from Fiumicino International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 14h 17m
- When
- Monday, Saturday, and Sunday
- Estimated price
- $500–2,000
Flights from Fiumicino International Airport to Des Moines via Charlotte
- Ave. Duration
- 16h 58m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $550–2,200
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Napoli Centrale to Roma Termini
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- $25–55
- Website
- https://www.italotreno.it/en
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Waterloo to Des Moines
- Ave. Duration
- 2h 25m
- Frequency
- 5 times a week
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Mason City to Des Moines
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $11–70
- Book at
- https://www.jeffersonlines.com
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Iowa City to Des Moines
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://burlingtontrailways.com
- Saver Fares
- $30–50
- Flexible Fares
- $45–65
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Italy Travel Guides
Read the travel guide














