There are 6 ways to get from Mytilene to Syracuse by plane, bus, car ferry, train, ferry, or busferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, bus
best- Fly from Mytilene International Airport Odysseas Elytis (MJT) to Catania–Fontanarossa Airport (CTA)MJT - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Greca
5h 24m€77–267Car ferry, bus, train
- Take the car ferry from Mytilene to Port of Thessaloniki
- Take the bus from Thessaloniki Macedonia KTEL Bus Station to Ioannina
- Take the bus from Ioannina to Vlore , station
- Take the bus from Vlorë to Taranto Port
- Take the train from Taranto to Lamezia Terme C.Ic
- Take the train from Lamezia Terme C. to SiracusaIc
33h 52mCar ferry, bus, ferry
- Take the car ferry from Mytilene to Port of Thessaloniki
- Take the bus from Thessaloniki Macedonia KTEL Bus Station to Igoumenitsa
- Take the ferry from Port of Igoumenitsa to Porto di Brindisi
- Take the bus from Brindisi to Siracusa - Corso Umberto
34h 52m€201–378Car ferry, bus, bus and ferry
- Take the car ferry from Mytilene to Port of Thessaloniki
- Take the bus from Thessaloníki to Vlorë
- Take the busferry from Vlorë to Catania Via D'Amico
- Take the bus from Catania Via Archimede to Siracusa - Von Platen
40h 37mFerry, bus, bus and ferry, train
- Take the ferry from Mytilene to ThessalonikiBsf
- Take the bus from Thessaloníki to Vlorë
- Take the busferry from Vlorë to Messina - Piazza della Repubblica
- Take the train from Messina Centrale to SiracusaRe
42h 46mFerry, bus, bus and ferry
- Take the ferry from Mytilene to ThessalonikiBsf
- Take the bus from Thessaloníki to Vlore , station
- Take the busferry from Vlorë to Catania Via D'Amico
- Take the bus from Catania Via Archimede to Siracusa - Von Platen
43h 7m
Mytilene International Airport Odysseas Elytis (MJT) to Catania–Fontanarossa Airport (CTA) flights
Questions & Answers
The cheapest way to get from Mytilene to Syracuse is to fly and bus which costs €75 - €270 and takes 5h 24m.
The fastest way to get from Mytilene to Syracuse is to fly and bus which takes 5h 24m and costs €75 - €270.
The distance between Mytilene and Syracuse is 1088 km.
The best way to get from Mytilene to Syracuse without a car is to car ferry and bus and train which takes 33h 52m and costs .
It takes approximately 5h 24m to get from Mytilene to Syracuse, including transfers.
Syracuse is 1h behind Mytilene. It is currently 5:37 PM in Mytilene and 4:37 PM in Syracuse.
There are 2831+ hotels available in Syracuse.
What companies run services between Mytilene, Greece and Syracuse, Italy?
There is no direct connection from Mytilene to Syracuse. However, you can take the taxi to Mytilene International Airport Odysseas Elytis (MJT) airport, fly to Catania–Fontanarossa Airport (CTA), walk to Catania Airport, then take the bus to Siracusa - v.le Scala Greca. Alternatively, you can take a car ferry from Mytilene to Siracusa via Port of Thessaloniki, Thessaloniki Macedonia KTEL Bus Station, Ioannina, Vlore , station, Vlorë, Taranto Port, Taranto, and Lamezia Terme C. in around 33h 52m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- en.aegeanair.com
Flights from Mytilene International Airport Odysseas Elytis to Catania–Fontanarossa Airport via Athens
- Ave. Duration
- 5h 35m
- When
- Thursday and Sunday
- Estimated price
- €70–260
- Website
- ryanair.com
Flights from Mytilene International Airport Odysseas Elytis to Catania–Fontanarossa Airport via Athens
- Ave. Duration
- 4h
- When
- Monday
- Estimated price
- €65–250
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Taranto to Lamezia Terme C.
- Ave. Duration
- 2h 40m
- Frequency
- 3 times a day
- Estimated price
- €12–60
- Website
- https://www.trenitalia.com/en.html
Train from Lamezia Terme C. to Siracusa
- Ave. Duration
- 5h 45m
- Frequency
- Once daily
- Estimated price
- €18–25
- Website
- https://www.trenitalia.com/en.html
- 2nd Class
- €18–25
Train from Messina Centrale to Siracusa
- Ave. Duration
- 2h 38m
- Frequency
- Twice daily
- Estimated price
- €15–21
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Messina Centrale to Siracusa
- Ave. Duration
- 2h 45m
- Frequency
- Every 4 hours
- Estimated price
- €10–35
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €23–35
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €4–7
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - Von Platen
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €5–8
- Schedules at
- interbus.it
- Phone
- +30 26510 25014
- ktelioa@otenet.gr
- Website
- ktelioannina.gr
Bus from Thessaloniki Macedonia KTEL Bus Station to Ioannina
- Ave. Duration
- 3h 30m
- Frequency
- 5 times a day
- Estimated price
- €24–35
- Schedules at
- ktelioannina.gr
- Book at
- eticket.ktelioannina.gr
- Phone
- +355 69 661 4303
- likospartak@gmail.com
- Website
- likokostatours.weebly.com
Bus from Ioannina to Vlore , station
- Ave. Duration
- 3h 6m
- Frequency
- Once daily
- Schedules at
- facebook.com
Bus from Thessaloníki to Vlore , station
- Ave. Duration
- 9h 16m
- Frequency
- Once daily
- Schedules at
- facebook.com
- Phone
- +393293958604
- info@pistoiaviaggi.com
- Website
- pistoia-viaggi.it
Bus from Vlorë to Taranto Port
- Ave. Duration
- 6h 36m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
Busferry from Vlorë to Catania Via D'Amico
- Ave. Duration
- 19h 50m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
Busferry from Vlorë to Messina - Piazza della Repubblica
- Ave. Duration
- 16h 56m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
- Phone
- +30 2665 0 22309
- info@ktel-thesprotias.gr
- Website
- ktel-thesprotias.gr
Bus from Thessaloniki Macedonia KTEL Bus Station to Igoumenitsa
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Estimated price
- €35–55
- Schedules at
- ktel-thesprotias.gr
- Book at
- ktelbus.gr
- Phone
- +39 0912742800
- info@saistrasporti.it
- Website
- saistrasporti.it
Bus from Brindisi to Siracusa - Corso Umberto
- Ave. Duration
- 9h 15m
- Frequency
- Twice daily
- Estimated price
- €30–45
- Website
- https://saistrasporti.it/en-US
- Phone
- +30 2310241545
- crazy.holidays.tours@gmail.com
- Website
- crazyholidays.gr
Bus from Thessaloníki to Vlorë
- Ave. Duration
- 9h 45m
- Frequency
- Once daily
- Estimated price
- €40–70
- Website
- https://www.crazyholidays.gr/root.en.aspx
- Phone
- +30 210 4121001
- info@seajets.gr
- Website
- seajets.com
Car ferry from Mytilene to Port of Thessaloniki
- Ave. Duration
- 7h 10m
- Frequency
- Once a week
- Estimated price
- €85–210
- Website
- https://www.seajets.com/
- Deck Fare Economy
- €85–130
- Deck Fare Economy & Car less than 4.25m
- €150–210
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Ferry from Port of Igoumenitsa to Porto di Brindisi
- Ave. Duration
- 9h
- Frequency
- Twice daily
- Estimated price
- €40–65
- Website
- https://www.grimaldi-lines.com/en/
Ferry from Mytilene to Thessaloniki
- Ave. Duration
- 10h 5m
- Frequency
- Once a week
- Estimated price
- €40–110
- Website
- https://www.bluestarferries.com/en-gb/
- Economy
- €40–60
- 2 Bed Inside Cabin
- €70–90
- 4 Bed Outside Cabin
- €65–85
- 2 Bed Lux Cabin
- €90–110
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Travelling by boat in Italy
Read the travel guide



































