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How to get fromMystic to Buffaloby train, plane, train (Amtrak), bus or car

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There are 9 ways to get from Mystic to Buffalo by train, plane, train (Amtrak), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Boston Logan Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Mystic Station to Bostontrain train
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    6h 3m
    $138–1,135

  2. Train, bus

    cheapest
    1. Take the train from Mystic Station to New Haventrain train
    2. Take the bus from New Haven Union Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York Midtown to Buffalobus bus
    13h 37m
    $68–335

  3. Train via New York

    1. Take the train from Mystic Station to Ny Moynihan Train Hall At Penn Stationtrain train Northeast Regional
    2. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    12h 28m
    $79–368

  4. Drive 441.8 mi

    1. Drive from Mystic to Buffalocar car 441.8 mi
    8h 6m
    $81–117

  5. Train, train to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Mystic Station to Stamford Amtrak Stationtrain train
    2. Take the train from Stamford to 125th Street - Harlemtrain train
    3. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    7h 27m
    $150–1,134

  6. Train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Mystic Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    7h 26m
    $136–1,047

  7. Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Mystic Station to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    7h 42m
    $125–1,035

  8. Train to Boston Logan Airport, fly to Rochester, bus

    1. Take the train from Mystic Station to Bostontrain train
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester, NY to Buffalo, NYbus bus
    8h
    $228–990

  9. Train (Amtrak)

    1. Take the train from Mystic Station to Ny Moynihan Train Hall At Penn Stationtrain train Northeast Regional
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    12h 48m
    $84–388

Mystic to Buffalo by train

Calendar7Weekly Trains
Duration12h 28mAverage Duration
Ticket$79Cheapest Price
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Questions & Answers

What companies run services between Mystic, CT, USA and Buffalo, NY, USA?

You can take a train from Mystic Station to Buffalo via Ny Moynihan Train Hall At Penn Station and New York Penn Station in around 12h 28m.

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