There are 6 ways to get from Myrtle Beach to Siesta Key by plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Sarasota–Bradenton International Airport
best- Fly from Myrtle Beach (MYR) to Sarasota–Bradenton International Airport (SRQ)plane MYR - SRQ
5h 3m$182–616Bus, train
cheapest- Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
- Take the train from Charleston Amtrak Station to Jacksonvilletrain
- Take the train from Jacksonville to Tampatrain
- Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus
18h 24m$102–207Bus
- Take the bus from Myrtle Beach, SC to Florencebus
- Take the bus from Florence Bus Station to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Centerbus
17h 36m$112–306Drive 576.2 mi
- Drive from Myrtle Beach to Siesta Keycar 576.2 mi
10h 47m$106–152Fly to Tampa, bus
- Fly from Myrtle Beach (MYR) to Tampa (TPA)plane MYR - TPA
- Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus
6h 42m$137–358Bus, train, Amtrak Thruway
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
- Take the train from Charleston Amtrak Station to Orlandotrain
- Take the bus from Orlando, FL to Sarasota Amtrak Bus Stopbus
18h 30m
Myrtle Beach to Siesta Key by bus
Questions & Answers
The cheapest way to get from Myrtle Beach to Siesta Key is to drive which costs $100 - $160 and takes 10h 47m.
The fastest way to get from Myrtle Beach to Siesta Key is to fly which takes 5h 3m and costs $180 - $650.
No, there is no direct bus from Myrtle Beach to Siesta Key. However, there are services departing from Myrtle Beach, SC and arriving at Ocean Blvd @ Avenida Madera via Florence Bus Station, Orlando Bus Station and Cattlemen Transit Station. The journey, including transfers, takes approximately 17h 36m.
The distance between Myrtle Beach and Siesta Key is 506 miles. The road distance is 579.6 miles.
The best way to get from Myrtle Beach to Siesta Key without a car is to bus which takes 17h 36m and costs $110 - $310.
It takes approximately 5h 3m to get from Myrtle Beach to Siesta Key, including transfers.
Myrtle Beach to Siesta Key bus services, operated by Southeastern Stages, depart from Myrtle Beach, SC station.
The best way to get from Myrtle Beach to Siesta Key is to fly which takes 5h 3m and costs $180 - $650. Alternatively, you can bus, which costs $110 - $310 and takes 17h 36m.
Myrtle Beach to Siesta Key bus services, operated by Southeastern Stages, arrive at Florence station.
Yes, the driving distance between Myrtle Beach to Siesta Key is 580 miles. It takes approximately 10h 47m to drive from Myrtle Beach to Siesta Key.
What companies run services between Myrtle Beach, SC, USA and Siesta Key, FL, USA?
Delta and American Airlines fly from Myrtle Beach (MYR) to Sarasota–Bradenton International Airport (SRQ) every 4 hours. Alternatively, you can take a bus from Myrtle Beach, SC to Ocean Blvd @ Avenida Madera via Florence, Florence Bus Station, Orlando Bus Station, Sarasota Cattlemen Transfer Center, and Cattlemen Transit Station in around 17h 36m.
- Website
- aa.com
Flights from Myrtle Beach to Sarasota–Bradenton International Airport via Charlotte
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $90–550
Flights from Myrtle Beach to Tampa via Charlotte
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $60–360
- Website
- delta.com
Flights from Myrtle Beach to Sarasota–Bradenton International Airport via Atlanta
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $95–550
Flights from Myrtle Beach to Tampa via Atlanta
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $65–370
- Website
- flybreeze.com
Flights from Myrtle Beach to Tampa
- Ave. Duration
- 1h 42m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Charleston Amtrak Station to Jacksonville
- Ave. Duration
- 4h 28m
- Frequency
- Once daily
- Estimated price
- $50–100
- Website
- https://www.amtrak.com/home.html
Train from Jacksonville to Tampa
- Ave. Duration
- 5h 29m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- https://www.amtrak.com/home.html
Train from Charleston Amtrak Station to Orlando
- Ave. Duration
- 8h 8m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Myrtle Beach, SC to Florence
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $25–95
- Schedules at
- southeasternstages.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Myrtle Beach, SC to Florence
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $26–55
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Charleston Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $11–15
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Florence Bus Station to Orlando Bus Station
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- $60–170
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Sarasota Cattlemen Transfer Center
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $24–40
- Schedules at
- flixbus.com
Bus from Tampa Bus Station to Sarasota Cattlemen Transfer Center
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- $13–22
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Orlando, FL to Sarasota Amtrak Bus Stop
- Ave. Duration
- 4h 5m
- Frequency
- Twice daily
- Website
- https://www.amtrak.com/home.html
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 509+ hotels available in Siesta Key.








