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How to get fromMyrtle Beach to Siesta Keyby plane, bus (Greyhound, Flixbus), bus, train or car

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There are 6 ways to get from Myrtle Beach to Siesta Key by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Sarasota–Bradenton International Airport

    best
    1. Fly from Myrtle Beach (MYR) to Sarasota–Bradenton International Airport (SRQ)planeMYR - SRQ
    5h 15m
    $182–666

  2. Drive 576.2 mi

    cheapest
    1. Drive from Myrtle Beach to Siesta Keycar576.2 mi
    10h 41m
    $106–152

  3. Bus

    1. Take the bus from Myrtle Beach, SC to Florencebus
    2. Take the bus from Florence Bus Station to Orlando Bus Stationbus
    3. Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Centerbus
    17h 36m
    $127–331

  4. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
    2. Take the train from Charleston Amtrak Station to Jacksonvilletrain
    3. Take the train from Jacksonville to Tampatrain
    4. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus
    18h 28m
    $128–280

  5. Fly to Tampa, bus

    1. Fly from Myrtle Beach (MYR) to Tampa (TPA)planeMYR - TPA
    2. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus
    6h 43m
    $147–378

  6. Bus, train, Amtrak Thruway

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
    2. Take the train from Charleston Amtrak Station to Orlandotrain
    3. Take the bus from Orlando, FL to Sarasota Amtrak Bus Stopbus
    18h 30m

Myrtle Beach to Siesta Key by bus

Calendar7Weekly Buses
Duration17h 36mAverage Duration
Ticket$127Cheapest Price
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Questions & Answers

What companies run services between Myrtle Beach, SC, USA and Siesta Key, FL, USA?

American Airlines, Delta, and Southwest Airlines fly from Myrtle Beach (MYR) to Sarasota–Bradenton International Airport (SRQ) 4 times a day. Alternatively, you can take a bus from Myrtle Beach, SC to Ocean Blvd @ Avenida Madera via Florence, Florence Bus Station, Orlando Bus Station, Sarasota Cattlemen Transfer Center, and Cattlemen Transit Station in around 17h 36m.

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