Rome2Rio

How to get fromMyrtle Beach to Sebastianby plane, bus (Greyhound, Flixbus), bus, train, shuttle or car

Find Transport to Sebastian

See all options

There are 6 ways to get from Myrtle Beach to Sebastian by plane, bus (Greyhound, Flixbus), bus, train, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Melbourne International Airport

    best
    1. Fly from Myrtle Beach (MYR) to Melbourne International Airport (MLB)planeMYR - MLB
    4h 29m
    $140–452

  2. Drive 528.4 mi

    cheapest
    1. Drive from Myrtle Beach to Sebastiancar528.4 mi
    9h 28m
    $97–140

  3. Bus

    1. Take the bus from Myrtle Beach, SC to Florencebus
    2. Take the bus from Florence Bus Station to Jacksonvillebus
    3. Take the bus from Jacksonville to Sebastianbus
    14h 6m
    $116–282

  4. Bus, train, shuttle

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
    2. Take the train from Charleston Amtrak Station to Delandtrain
    3. Take the train from DeLand to Sand Lake Roadtrain
    4. Take a shuttle bus from Orlando Airport to Sebastian, FL - BPshuttle
    15h 36m
    $176–505

  5. Fly to Orlando, shuttle

    1. Fly from Myrtle Beach (MYR) to Orlando (MCO)planeMYR - MCO
    2. Take a shuttle bus from Orlando Airport to Sebastian, FL - BPshuttle
    4h 18m
    $165–355

  6. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
    2. Take the train from Charleston Amtrak Station to Jacksonvilletrain
    3. Take the bus from Jacksonville to Sebastianbus
    14h 59m
    $127–261

Myrtle Beach (MYR) to Melbourne International Airport (MLB) flights

Calendar45Weekly Planes
Duration5h 15mAverage Duration
Ticket$67Cheapest Price
See schedules

Questions & Answers

What companies run services between Myrtle Beach, SC, USA and Sebastian, FL, USA?

American Airlines and Delta fly from Myrtle Beach (MYR) to Melbourne International Airport (MLB) every 4 hours. Alternatively, you can take a bus from Myrtle Beach, SC to Sebastian via Florence, Florence Bus Station, Jacksonville, and Sebastian in around 14h 6m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Myrtle Beach

Trips to Sebastian

Popular routes