There are 8 ways to get from Myrtle Beach to San Diego by plane, bus (Greyhound, Amtrak), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Myrtle Beach
best- Fly from Myrtle Beach (MYR) to San Diego International Airport (SAN)MYR - SAN
7h 11m$210–862Bus
- Take the bus from Myrtle Beach Bus Station to Atlanta Bus Station
- Take the bus from Atlanta Bus Station to Dallas Bus Station
- Take the bus from Dallas Bus Station to Los Angeles Union Station
- Take the bus from Los Angeles to San Diego
2d 15hBus, train
- Take the bus from Myrtle Beach, SC to Florence
- Take the bus from Florence Bus Station to Fayetteville Bus Station
- Take the train from Fayetteville Amtrak Station to Petersburg Amtrak Station
- Take the train from Petersburg Amtrak Station to Chicago Union Station
- Take the train from Chicago Union Station to Fullerton Amtrak Station
- Take the train from Fullerton Amtrak Station to San Diego
3d 5h$450–1,953Drive 2,488.7 mi
- Drive from Myrtle Beach to San Diego2,488.7 mi
39h 34m$455–656Bus to Wilmington International Airport, fly
- Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transit
- Fly from Wilmington International Airport (ILM) to San Diego International Airport (SAN)ILM - SAN
10h 18m$221–895Bus to Florence Regional Airport, fly
- Take the bus from Myrtle Beach, SC to Florence
- Fly from Florence Regional Airport (FLO) to San Diego International Airport (SAN)FLO - SAN
11h 30m$236–957Bus, train via New Orleans
- Take the bus from Myrtle Beach, SC to Charlotte Bus Station
- Take the train from Charlotte Amtrak Station to New Orleans Union Passenger Terminal
- Take the train from New Orleans Union Passenger Terminal to Los Angeles
- Take the train from Los Angeles to San Diego
3d 6h$479–2,628Bus, train via Atlanta
- Take the bus from Myrtle Beach, SC to Columbia
- Take the bus from Columbia to Atlanta
- Take the bus from Atlanta Bus Station to St Louis Bus Station
- Take the train from St. Louis to Los Angeles
- Take the bus from Los Angeles to San Diego
3d 13h
Myrtle Beach (MYR) to San Diego International Airport (SAN) flights
Questions & Answers
The cheapest way to get from Myrtle Beach to San Diego is to fly which costs $210 - $900 and takes 7h 11m.
The fastest way to get from Myrtle Beach to San Diego is to fly which takes 7h 11m and costs $210 - $900.
No, there is no direct bus from Myrtle Beach station to San Diego. However, there are services departing from Myrtle Beach Bus Station and arriving at San Diego via Atlanta Bus Station, Dallas Bus Station and Los Angeles. The journey, including transfers, takes approximately 2 days 15h.
The distance between Myrtle Beach and San Diego is 2216 miles. The road distance is 2503.2 miles.
The best way to get from Myrtle Beach to San Diego without a car is to bus which takes 2 days 15h and costs .
It takes approximately 7h 11m to get from Myrtle Beach to San Diego, including transfers.
Myrtle Beach to San Diego bus services, operated by Greyhound USA, depart from Myrtle Beach Bus Station.
The best way to get from Myrtle Beach to San Diego is to fly which takes 7h 11m and costs $210 - $900. Alternatively, you can bus, which costs and takes 2 days 15h.
Myrtle Beach to San Diego bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
San Diego is 3h behind Myrtle Beach. It is currently 7:32 PM in Myrtle Beach and 4:32 PM in San Diego.
What companies run services between Myrtle Beach, SC, USA and San Diego, CA, USA?
Southwest Airlines, American Airlines, and two other airlines fly from Myrtle Beach (MYR) to San Diego International Airport (SAN) 5 times a day. Alternatively, you can take a bus from Myrtle Beach Bus Station to San Diego via Atlanta Bus Station, Dallas Bus Station, Los Angeles Union Station, and Los Angeles in around 2d 15h.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Myrtle Beach to San Diego International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 38m
- When
- Every day
- Estimated price
- $200–850
Flights from Wilmington International Airport to San Diego International Airport via Charlotte
- Ave. Duration
- 8h 25m
- When
- Every day
- Estimated price
- $190–850
Flights from Wilmington International Airport to San Diego International Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 32m
- When
- Every day
- Estimated price
- $190–850
Flights from Wilmington International Airport to San Diego International Airport via Chicago O'Hare
- Ave. Duration
- 8h 21m
- When
- Saturday
- Estimated price
- $210–900
Flights from Florence Regional Airport to San Diego International Airport via Charlotte
- Ave. Duration
- 9h 46m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–850
Flights from Florence Regional Airport to San Diego International Airport via Charlotte, Phoenix
- Ave. Duration
- 10h 19m
- When
- Every day
- Estimated price
- $200–850
- Website
- delta.com
Flights from Myrtle Beach to San Diego International Airport via Atlanta
- Ave. Duration
- 8h 27m
- When
- Every day
- Estimated price
- $200–850
Flights from Wilmington International Airport to San Diego International Airport via Atlanta
- Ave. Duration
- 8h 40m
- When
- Every day
- Estimated price
- $190–850
Flights from Wilmington International Airport to San Diego International Airport via Minneapolis
- Ave. Duration
- 8h 42m
- When
- Saturday and Sunday
- Estimated price
- $220–900
- Website
- southwest.com
Flights from Myrtle Beach to San Diego International Airport via Dallas
- Ave. Duration
- 7h 5m
- When
- Sunday
- Estimated price
- $200–850
Flights from Myrtle Beach to San Diego International Airport via Nashville
- Ave. Duration
- 7h 10m
- When
- Thursday and Friday
- Estimated price
- $200–850
Flights from Myrtle Beach to San Diego International Airport via Denver
- Ave. Duration
- 7h 10m
- When
- Monday, Thursday, and Friday
- Estimated price
- $210–900
Flights from Myrtle Beach to San Diego International Airport via Houston Hobby Apt
- Ave. Duration
- 8h 25m
- When
- Saturday
- Estimated price
- $210–900
- Website
- united.com
Flights from Myrtle Beach to San Diego International Airport via Denver
- Ave. Duration
- 8h
- When
- Saturday
- Estimated price
- $210–900
Flights from Wilmington International Airport to San Diego International Airport via Denver
- Ave. Duration
- 7h 30m
- When
- Saturday
- Estimated price
- $200–850
Flights from Wilmington International Airport to San Diego International Airport via Chicago O'Hare
- Ave. Duration
- 14h 10m
- When
- Every day
- Estimated price
- $210–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Fayetteville Amtrak Station to Petersburg Amtrak Station
- Ave. Duration
- 2h 53m
- Frequency
- Twice daily
- Estimated price
- $24–90
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $26–50
- Coach Seat short notice purchase
- $24–90
- Business - advance purchase
- $30–170
- Business Class
- $55–230
Train from Petersburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 21h 50m
- Frequency
- Once daily
- Estimated price
- $180–1,200
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Twice daily
- Estimated price
- $160–440
- Website
- https://www.amtrak.com/home.html
Train from Fullerton Amtrak Station to San Diego
- Ave. Duration
- 2h 23m
- Frequency
- Every 2 hours
- Estimated price
- $32–34
- Website
- https://www.amtrak.com/home.html
Train from Charlotte Amtrak Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 19h 7m
- Frequency
- Once daily
- Estimated price
- $150–380
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Los Angeles
- Ave. Duration
- 46h 35m
- Frequency
- 3 times a week
- Estimated price
- $230–2,100
- Website
- https://www.amtrak.com/home.html
Train from Los Angeles to San Diego
- Ave. Duration
- 2h 54m
- Frequency
- Every 2 hours
- Estimated price
- $33–39
- Website
- https://www.amtrak.com/home.html
Train from St. Louis to Los Angeles
- Ave. Duration
- 2d 11h
- Frequency
- 3 times a week
- Estimated price
- $180–1,300
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Myrtle Beach Bus Station to Atlanta Bus Station
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Dallas Bus Station
- Ave. Duration
- 17h 55m
- Frequency
- 3 times a day
- Estimated price
- $65–210
- Website
- https://www.greyhound.com/
Bus from Dallas Bus Station to Los Angeles Union Station
- Ave. Duration
- 30h 15m
- Frequency
- Twice daily
- Estimated price
- $110–310
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach, SC to Florence
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $26–55
- Website
- https://www.greyhound.com/
Bus from Florence Bus Station to Fayetteville Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $28–60
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transit
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $17–27
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Los Angeles to San Diego
- Ave. Duration
- 3h
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Myrtle Beach, SC to Florence
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $25–95
- Schedules at
- southeasternstages.com
Bus from Florence Bus Station to Fayetteville Bus Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $29–95
- Schedules at
- southeasternstages.com
Bus from Myrtle Beach, SC to Charlotte Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- southeasternstages.com
Bus from Myrtle Beach, SC to Columbia
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $45–100
- Schedules at
- southeasternstages.com
Bus from Columbia to Atlanta
- Ave. Duration
- 4h 31m
- Frequency
- 4 times a day
- Estimated price
- $60–110
- Schedules at
- southeasternstages.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Atlanta Bus Station to St Louis Bus Station
- Ave. Duration
- 10h 40m
- Frequency
- Once daily
- Estimated price
- $75–150
- Schedules at
- flixbus.com
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More Questions & Answers
Yes, the driving distance between Myrtle Beach to San Diego is 2503 miles. It takes approximately 39h 34m to drive from Myrtle Beach to San Diego.
There are 2000+ hotels available in San Diego.











