What is the cheapest way to get from Myrtle Beach to Key West?

The cheapest way to get from Myrtle Beach to Key West is to drive which costs $150 - $220 and takes 15h 12m.

What is the fastest way to get from Myrtle Beach to Key West?

The fastest way to get from Myrtle Beach to Key West is to fly which takes 4h 47m and costs $110 - $550.

Is there a direct bus between Myrtle Beach and Key West?

No, there is no direct bus from Myrtle Beach station to Key West. However, there are services departing from Myrtle Beach Bus Station and arriving at N Roosevelt & 3rd Street via Florence Bus Station, Orlando Bus Station, Orlando, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 24h 38m.

How far is it from Myrtle Beach to Key West?

The distance between Myrtle Beach and Key West is 662 miles. The road distance is 839.2 miles.

How do I travel from Myrtle Beach to Key West without a car?

The best way to get from Myrtle Beach to Key West without a car is to bus and train and shuttle which takes 24h 37m and costs $250 - $550.

How long does it take to get from Myrtle Beach to Key West?

It takes approximately 4h 47m to get from Myrtle Beach to Key West, including transfers.

Where do I catch the Myrtle Beach to Key West bus from?

Myrtle Beach to Key West bus services, operated by Greyhound USA, depart from Myrtle Beach Bus Station.

Bus or fly from Myrtle Beach to Key West?

The best way to get from Myrtle Beach to Key West is to fly which takes 4h 47m and costs $110 - $550. Alternatively, you can bus, which costs $140 - $550 and takes 24h 38m.

Where does the Myrtle Beach to Key West bus arrive?

Myrtle Beach to Key West bus services, operated by Greyhound USA, arrive at Florence Bus Station.

Can I drive from Myrtle Beach to Key West?

Yes, the driving distance between Myrtle Beach to Key West is 839 miles. It takes approximately 15h 12m to drive from Myrtle Beach to Key West.

Where can I stay near Key West?

There are 792+ hotels available in Key West.

Myrtle Beach to Key West - 4 ways to travel via train, plane, bus, and shuttle

There are 4 ways to get from Myrtle Beach to Key West by plane, bus, train, shuttle, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly
best
1. Fly from Myrtle Beach (MYR) to Key West International Airport (EYW)MYR - EYW
4h 47m
$116–515
Bus, train, shuttle
1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Station
2. Take the train from Charleston Amtrak Station to Miami Amtrak Station
3. Take a shuttle bus from Miami, FL - International Airport to Key West, FL
24h 37m
$250–514
Bus
1. Take the bus from Myrtle Beach Bus Station to Florence Bus Station
2. Take the bus from Florence Bus Station to Orlando Bus Station
3. Take the bus from Orlando to Miami Airport Station
4. Take the bus from Miami Airport Station to Big Pine Key
5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
24h 38m
$145–543
Drive 834.3 mi
1. Drive from Myrtle Beach to Key West834.3 mi
15h 12m
$153–220

Myrtle Beach to Key West by bus, train, foot, tram, and shuttle

7Weekly Services

24h 37mAverage Duration

$250Cheapest Price

See schedules

Questions & Answers

Map of how to get from Myrtle Beach to Key West.

Launch map view

Distance: 658.2 mi
Duration: 4h 47m

What companies run services between Myrtle Beach, SC, USA and Key West, FL, USA?

Delta and American Airlines fly from Myrtle Beach (MYR) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to N Roosevelt & 3rd Street via Florence Bus Station, Orlando Bus Station, Orlando, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 24h 38m.

Airlines

Train operators

Bus operators

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