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How to get fromMyrtle Beach to Key Westby plane, bus, train, shuttle, bus (Greyhound, Flixbus) or car

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There are 4 ways to get from Myrtle Beach to Key West by plane, bus, train, shuttle, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Myrtle Beach (MYR) to Key West International Airport (EYW)plane plane MYR - EYW
    3h 43m
    $121–575
  2. Bus, train, shuttle

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Miami Amtrak Stationtrain train
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    24h 37m
    $270–392
  3. Bus

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    30h 16m
    $128–303
  4. Drive 834.3 mi

    1. Drive from Myrtle Beach to Key Westcar car 834.3 mi
    15h 20m
    $153–220

Myrtle Beach (MYR) to Key West International Airport (EYW) flights

Calendar48Weekly Planes
Duration5hAverage Duration
Ticket$94Cheapest Price
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Questions & Answers

What companies run services between Myrtle Beach, SC, USA and Key West, FL, USA?

Spirit Airlines, American Airlines, and Delta fly from Myrtle Beach (MYR) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to N Roosevelt & 3rd Street via Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 30h 16m.

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