There are 4 ways to get from Myrtle Beach to Key West by plane, bus, train, shuttle, bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Myrtle Beach (MYR) to Key West International Airport (EYW)plane MYR - EYW
3h 43m$121–575Bus, train, shuttle
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
- Take the train from Charleston Amtrak Station to Miami Amtrak Stationtrain
- Take a shuttle bus from Miami, FL - International Airport to Key West, FL
24h 37m$270–392Bus
- Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
30h 16m$128–303Drive 834.3 mi
- Drive from Myrtle Beach to Key Westcar 834.3 mi
15h 20m$153–220
Myrtle Beach (MYR) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Myrtle Beach to Key West is to drive which costs $150 - $220 and takes 15h 20m.
The fastest way to get from Myrtle Beach to Key West is to fly which takes 3h 43m and costs $120 - $600.
No, there is no direct bus from Myrtle Beach station to Key West. However, there are services departing from Myrtle Beach Bus Station and arriving at N Roosevelt & 3rd Street via Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 30h 16m.
The distance between Myrtle Beach and Key West is 662 miles. The road distance is 839.2 miles.
The best way to get from Myrtle Beach to Key West without a car is to bus and train and shuttle which takes 24h 37m and costs $270 - $400.
It takes approximately 3h 43m to get from Myrtle Beach to Key West, including transfers.
Myrtle Beach to Key West bus services, operated by Greyhound USA, depart from Myrtle Beach Bus Station.
The best way to get from Myrtle Beach to Key West is to fly which takes 3h 43m and costs $120 - $600. Alternatively, you can bus, which costs $120 - $310 and takes 30h 16m.
Myrtle Beach to Key West bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Myrtle Beach to Key West is 839 miles. It takes approximately 15h 20m to drive from Myrtle Beach to Key West.
What companies run services between Myrtle Beach, SC, USA and Key West, FL, USA?
Spirit Airlines, American Airlines, and Delta fly from Myrtle Beach (MYR) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to N Roosevelt & 3rd Street via Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 30h 16m.
- Website
- aa.com
Flights from Myrtle Beach to Key West International Airport via Charlotte
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $100–550
- Website
- delta.com
Flights from Myrtle Beach to Key West International Airport via Atlanta
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $110–550
- Website
- spirit.com
Flights from Myrtle Beach to Key West International Airport via Fort Lauderdale
- Ave. Duration
- 4h 21m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Charleston Amtrak Station to Miami Amtrak Station
- Ave. Duration
- 14h 3m
- Frequency
- Once daily
- Estimated price
- $85–170
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Myrtle Beach Bus Station to Charleston Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $12–14
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Atlanta Bus Station
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $21–30
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key West, FL
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 13h 30m
- Frequency
- Once daily
- Estimated price
- $55–170
- Schedules at
- flixbus.com
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Want to know more about travelling around United States
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