What is the cheapest way to get from Myrtle Beach to Key Largo?

The cheapest way to get from Myrtle Beach to Key Largo is to drive which costs $130 - $200 and takes 12h 57m.

What is the fastest way to get from Myrtle Beach to Key Largo?

The fastest way to get from Myrtle Beach to Key Largo is to fly and shuttle which takes 4h 41m and costs $170 - $420.

Is there a direct bus between Myrtle Beach and Key Largo?

No, there is no direct bus from Myrtle Beach to Key Largo. However, there are services departing from Myrtle Beach, SC and arriving at Key Largo Bus Stop via Florence Bus Station, Orlando Bus Station and Miami Airport Station. The journey, including transfers, takes approximately 19h 32m.

How far is it from Myrtle Beach to Key Largo?

The distance between Myrtle Beach and Key Largo is 621 miles. The road distance is 741.6 miles.

How do I travel from Myrtle Beach to Key Largo without a car?

The best way to get from Myrtle Beach to Key Largo without a car is to bus which takes 19h 32m and costs $130 - $390.

How long does it take to get from Myrtle Beach to Key Largo?

It takes approximately 4h 41m to get from Myrtle Beach to Key Largo, including transfers.

Where do I catch the Myrtle Beach to Key Largo bus from?

Myrtle Beach to Key Largo bus services, operated by Southeastern Stages, depart from Myrtle Beach, SC station.

Where does the Myrtle Beach to Key Largo bus arrive?

Myrtle Beach to Key Largo bus services, operated by Southeastern Stages, arrive at Florence station.

Can I drive from Myrtle Beach to Key Largo?

Yes, the driving distance between Myrtle Beach to Key Largo is 742 miles. It takes approximately 12h 57m to drive from Myrtle Beach to Key Largo.

How do I get a bus ticket from Myrtle Beach to Key Largo?

Book your Myrtle Beach to Key Largo bus tickets online with FlixBus.

Where can I stay near Key Largo?

There are 302+ hotels available in Key Largo.

Myrtle Beach to Key Largo - 6 ways to travel via train, plane, shuttle, and bus

There are 6 ways to get from Myrtle Beach to Key Largo by plane, shuttle, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly Myrtle Beach to Fort Lauderdale–Hollywood International Airport, shuttle
best
1. Fly from Myrtle Beach (MYR) to Fort Lauderdale–Hollywood International Airport (FLL)MYR - FLL
2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
4h 41m
$175–412
Drive 737.2 mi
cheapest
1. Drive from Myrtle Beach to Key Largo737.2 mi
12h 57m
$135–195
Bus
1. Take the bus from Myrtle Beach, SC to Florence
2. Take the bus from Florence Bus Station to Orlando Bus Station
3. Take the bus from Orlando Bus Station to Miami Airport Station
4. Take the bus from Miami Airport Station to Key Largo Bus Stop
19h 32m
$138–387
Bus, train
1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Station
2. Take the train from Charleston Amtrak Station to Miami Amtrak Station
3. Take the bus from Dadeland South Metrorail Station to SW 344 St @ Park & Ride38 / ...
4. Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largo301
21h 9m
Fly Myrtle Beach to Miami International Airport, shuttle
1. Fly from Myrtle Beach (MYR) to Miami International Airport (MIA)MYR - MIA
2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
6h 35m
$160–482
Bus to Wilmington International Airport, fly to Miami International Airport, shuttle
1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transit
2. Fly from Wilmington International Airport (ILM) to Miami International Airport (MIA)ILM - MIA
3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
7h 17m
$271–604

Myrtle Beach to Key Largo by bus

7Weekly Buses

19h 32mAverage Duration

$138Cheapest Price

See schedules

Questions & Answers

Map of how to get from Myrtle Beach to Key Largo.

Launch map view

Distance: 617 mi
Duration: 4h 41m

What companies run services between Myrtle Beach, SC, USA and Key Largo, FL, USA?

You can take a bus from Myrtle Beach, SC to Key Largo Bus Stop via Florence, Florence Bus Station, Orlando Bus Station, and Miami Airport Station in around 19h 32m.

Airlines

Train operators

Bus operators

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