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How to get fromMyrtle Beach to Key Largoby plane, bus, train, car, or shuttle

Find Transport to Key Largo

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There are 5 ways to get from Myrtle Beach to Key Largo by plane, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Myrtle Beach to Miami International Airport, bus

    best
    1. Fly from Myrtle Beach (MYR) to Miami International Airport (MIA)plane plane MYR - MIA
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    6h 56m
    $85–361

  2. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Miami Amtrak Stationtrain train
    3. Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largobus bus 301
    20h 50m
    $214–447

  3. Drive 737.3 mi

    1. Drive from Myrtle Beach to Key Largocar car 737.3 mi
    13h 5m
    $135–195

  4. Fly Myrtle Beach to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Myrtle Beach (MYR) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane MYR - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    4h 41m
    $227–814

  5. Bus to Wilmington International Airport, fly to Miami International Airport, bus

    1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    2. Fly from Wilmington International Airport (ILM) to Miami International Airport (MIA)plane plane ILM - MIA
    3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    7h 5m
    $88–367

Myrtle Beach to Key Largo by bus, train, and foot

Calendar7Weekly Services
Duration20h 50mAverage Duration
Ticket$214Cheapest Price
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Questions & Answers

Map of how to get from Myrtle Beach to Key Largo.ExpandLaunch map view
  • Distance: 612.4 mi
  • Duration: 6h 56m

What companies run services between Myrtle Beach, SC, USA and Key Largo, FL, USA?

There is no direct connection from Myrtle Beach to Key Largo. However, you can take the taxi to Myrtle Beach (MYR) airport, fly to Miami International Airport (MIA), walk to Miami International Airport, take the vehicle to Miami Airport Station, walk to Miami, Airport Intermodal Station, then take the bus to Key Largo Bus Stop. Alternatively, you can take a bus from Myrtle Beach Bus Station to Mile Marker 98 Key Largo via Charleston Bus Station, Charleston Amtrak Station, Miami Station, Tri-Rail Station Rail Southbound, Dadeland South Stat.Rail Southbound, Dadeland South Metrorail Station, Sw 344 St Park-And-Ride, and W Palm Dr @ 3 Ave in around 20h 50m.

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