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How to get fromMyrtle Beach to Iowaby plane, bus (Greyhound, Flixbus), bus, train, or car

Find Transport to Iowa

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There are 8 ways to get from Myrtle Beach to Iowa by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from Myrtle Beach (MYR) to Des Moines (DSM)plane plane MYR - DSM
    4h 50m
    $110–447

  2. Fly to Quad City International Airport

    cheapest
    1. Fly from Myrtle Beach (MYR) to Quad City International Airport (MLI)plane plane MYR - MLI
    6h 10m
    $84–396

  3. Bus

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    4. Take the bus from Kansas City to Des Moinesbus bus
    31h
    $245–387

  4. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus bus
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    38h 7m
    $656–1,111

  5. Drive  1,183.9 mi

    1. Drive from Myrtle Beach to Des Moinescar car 1,183.9 mi
    21h 17m
    $217–313

  6. Fly to Omaha

    1. Fly from Myrtle Beach (MYR) to Omaha (OMA)plane plane MYR - OMA
    4h 57m
    $147–644

  7. Fly to The Eastern Iowa Airport

    1. Fly from Myrtle Beach (MYR) to The Eastern Iowa Airport (CID)plane plane MYR - CID
    6h 7m
    $127–454

  8. Bus, train via Galesburg

    1. Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus bus
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    39h 58m
    $721–1,216

Myrtle Beach to Iowa by bus

Calendar7Weekly Buses
Duration31hAverage Duration
Ticket$245Cheapest Price
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Comparing Your Travel Options

Map of how to get from Myrtle Beach to Iowa.ExpandLaunch map view
  • Distance: 978.7 mi
  • Duration: 4h 50m

What companies run services between Myrtle Beach, SC, USA and Iowa, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Myrtle Beach (MYR) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to Des Moines via Atlanta Bus Station, St Louis Bus Station, Kansas City Bus Station, and Kansas City in around 31h.

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Want to know more about travelling around United States

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