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How to get fromMyrtle Beach to Iowaby plane, bus (Greyhound, Flixbus), bus, train or car

Find Transport to Iowa

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There are 9 ways to get from Myrtle Beach to Iowa by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from Myrtle Beach (MYR) to Des Moines (DSM)plane plane MYR - DSM
    5h 1m
    $107–453

  2. Fly to Quad City International Airport

    cheapest
    1. Fly from Myrtle Beach (MYR) to Quad City International Airport (MLI)plane plane MYR - MLI
    6h 14m
    $82–414

  3. Bus

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    31h 59m
    $203–440

  4. Bus, train via Raleigh

    1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    2. Take the bus from Wilmington Cape Fear Public Transit to Raleigh Bus Stationbus bus
    3. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    39h 32m
    $335–726

  5. Drive 1,183.2 mi

    1. Drive from Myrtle Beach to Des Moinescar car 1,183.2 mi
    21h 20m
    $216–312

  6. Fly to Omaha

    1. Fly from Myrtle Beach (MYR) to Omaha (OMA)plane plane MYR - OMA
    5h 2m
    $265–1,242

  7. Fly to Waterloo Municipal Airport

    1. Fly from Myrtle Beach (MYR) to Waterloo Municipal Airport (ALO)plane plane MYR - ALO
    9h 51m
    $107–463

  8. Fly to The Eastern Iowa Airport, bus

    1. Fly from Myrtle Beach (MYR) to The Eastern Iowa Airport (CID)plane plane MYR - CID
    2. Take the bus from GTC Bay 9 to Court St Transportation Centerbus bus
    7h 51m

  9. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain train
    4. Take the bus from Chicago Bus Station to Iowa Citybus bus
    5. Take the bus from Iowa City to Des Moinesbus bus
    41h 9m
    $357–795

Myrtle Beach (MYR) to Des Moines (DSM) flights

Calendar58Weekly Planes
Duration6h 3mAverage Duration
Ticket$82Cheapest Price
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Questions & Answers

What companies run services between Myrtle Beach, SC, USA and Iowa, USA?

Delta, American Airlines, and United Airlines fly from Myrtle Beach (MYR) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to Des Moines via Atlanta Bus Station, Chicago Bus Station, and Des Moines in around 31h 59m.

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