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How to get fromMyrtle Beach to Indianapolisby plane, bus (Greyhound, Flixbus), car, bus or train

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There are 4 ways to get from Myrtle Beach to Indianapolis by plane, bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Myrtle Beach (MYR) to Indianapolis (IND)plane plane MYR - IND
    3h 2m
    $82–434
  2. Bus

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus Greyhound US0641
    2. Take the bus from Atlanta Bus Station to Indianapolisbus bus FlixBus 2512
    20h 35m
    $110–239
  3. Drive 718.1 mi

    1. Drive from Myrtle Beach to Indianapoliscar car 718.1 mi
    13h 25m
    $131–190
  4. Bus, train

    1. Take the bus from Myrtle Beach, SC to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Ashlandbus bus
    3. Take the train from Ashland Amtrak Station to Indianapolistrain train
    22h 56m
    $129–313

Myrtle Beach to Indianapolis by bus

Calendar7Weekly Buses
Duration20h 35mAverage Duration
Ticket$110Cheapest Price
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Questions & Answers

What companies run services between Myrtle Beach, SC, USA and Indianapolis, IN, USA?

Allegiant Air, American Airlines, and two other airlines fly from Myrtle Beach (MYR) to Indianapolis (IND) every 4 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to Indianapolis via Atlanta Bus Station in around 20h 35m.

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