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How to get fromMyrtle Beach to Durhamby bus (Greyhound), car, plane, bus, or train

Find Transport to Durham

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There are 5 ways to get from Myrtle Beach to Durham by bus (Greyhound), car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus bus Greyhound US0645S
    6h 23m
    $46–64

  2. Drive  182.7 mi

    cheapest
    1. Drive from Myrtle Beach to Durhamcar car 182.7 mi
    4h
    $34–49

  3. Fly to Raleigh-Durham International Airport

    1. Fly from Myrtle Beach (MYR) to Raleigh-Durham International Airport (RDU)plane plane MYR - RDU
    4h 40m
    $78–420

  4. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the train from Fayetteville Amtrak Station to Selma Stationtrain train
    3. Take the train from Selma Station to Durham Amtrak Stationtrain train
    7h 15m
    $83–135

  5. Fly to Piedmont Triad International Airport, train

    1. Fly from Myrtle Beach (MYR) to Piedmont Triad International Airport (GSO)plane plane MYR - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain train
    5h 22m
    $111–399

Myrtle Beach to Durham by bus (Greyhound)

Calendar7Weekly Buses
Duration6h 23mAverage Duration
Ticket$46Cheapest Price
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Comparing Your Travel Options

Map of how to get from Myrtle Beach to Durham.ExpandLaunch map view
  • Distance: 249.1 mi
  • Duration: 6h 23m

What companies run services between Myrtle Beach, SC, USA and Durham, NC, USA?

Greyhound USA operates a bus from Myrtle Beach Bus Station to Raleigh Bus Station once daily. Tickets cost $35–60 and the journey takes 4h 20m. Alternatively, American Airlines, Southwest Airlines, and three other airlines fly from Myrtle Beach (MYR) to Raleigh-Durham International Airport (RDU) hourly.

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