There are 10 ways to get from Muscatine to Lexington by bus (Greyhound), bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Muscatine, IA to Burlington, IA
- Take the bus from Burlington to Indianapolis Union Station
- Take the bus from Indianapolis Union Station to Lexington Bus Stop
14h 12m$142–278Drive 503.8 mi
cheapest- Drive from Muscatine to Lexington503.8 mi
9h 1m$92–133Bus, train
- Take the bus from Muscatine, IA to Burlington, IA
- Take the bus from Burlington to Galesburg
- Take the train from Galesburg Amtrak Station to Chicago Union Station
- Take the train from Chicago Union Station to Indianapolis
- Take the bus from Indianapolis Union Station to Lexington Bus Stop
19h 1m$157–338Bus to Quad City International Airport, fly to Blue Grass Airport
- Take the bus from Muscatine to Davenport
- Fly from Quad City International Airport (MLI) to Blue Grass Airport (LEX)MLI - LEX
10h 49m$165–844Bus, bus to The Eastern Iowa Airport, fly to Blue Grass Airport
- Take the bus from Muscatine to Davenport
- Take the bus from Davenport to Cedar Rapids Airport
- Fly from The Eastern Iowa Airport (CID) to Blue Grass Airport (LEX)CID - LEX
11h 39m$204–1,053Bus, train to Chicago Midway International Airport, fly to Louisville International Airport, drive
- Take the bus from Muscatine to Davenport
- Take the bus from Davenport to Naperville Amtrak
- Take the train from Naperville to Chicago Union Station
- Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)MDW - SDF
- Drive from Louisville International Airport (SDF) to Lexington
11h 19m$147–623Bus to Burlington Municipal Airport, fly to Blue Grass Airport
- Take the bus from Muscatine, IA to Burlington, IA
- Fly from Burlington Municipal Airport (BRL) to Blue Grass Airport (LEX)BRL - LEX
9h 24m$165–824Bus, bus to Peoria International Airport, fly to Blue Grass Airport
- Take the bus from Muscatine, IA to Burlington, IA
- Take the bus from Burlington to Peoria
- Fly from Peoria International Airport (PIA) to Blue Grass Airport (LEX)PIA - LEX
13h$169–864Bus, train to Chicago O'Hare International Airport, fly to Blue Grass Airport
- Take the bus from Muscatine to Davenport
- Take the bus from Davenport to Naperville Amtrak
- Take the train from Naperville to Chicago Union Station
- Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)ORD - LEX
12h 28m$155–734Bus to Dubuque Regional Airport, fly to Blue Grass Airport
- Take the bus from Muscatine to Dubuque Intermodal Transportation Center
- Fly from Dubuque Regional Airport (DBQ) to Blue Grass Airport (LEX)DBQ - LEX
10h 36m$203–958
Quad City International Airport (MLI) to Blue Grass Airport (LEX) flights
Questions & Answers
The cheapest way to get from Muscatine to Lexington is to drive which costs $90 - $140 and takes 9h 1m.
The fastest way to get from Muscatine to Lexington is to drive which takes 9h 1m and costs $90 - $140.
The distance between Muscatine and Lexington is 565 miles. The road distance is 506.8 miles.
The best way to get from Muscatine to Lexington without a car is to bus which takes 14h 12m and costs $140 - $280.
It takes approximately 14h 12m to get from Muscatine to Lexington, including transfers.
Lexington is 1h ahead of Muscatine. It is currently 4:36 AM in Muscatine and 5:36 AM in Lexington.
Yes, the driving distance between Muscatine to Lexington is 507 miles. It takes approximately 9h 1m to drive from Muscatine to Lexington.
There are 124+ hotels available in Lexington.
What companies run services between Muscatine, IA, USA and Lexington, KY, USA?
You can take a bus from City Hall to Lexington via Muscatine, IA, Burlington, IA, Burlington, Indianapolis Union Station, and Lexington Bus Stop in around 14h 12m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Quad City International Airport to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $120–750
Flights from Quad City International Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $180–950
Flights from Quad City International Airport to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $240–1,200
Flights from The Eastern Iowa Airport to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $150–950
Flights from The Eastern Iowa Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 7h 6m
- When
- Every day
- Estimated price
- $230–1,200
Flights from The Eastern Iowa Airport to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 24m
- When
- Every day
- Estimated price
- $300–1,400
Flights from Burlington Municipal Airport to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $120–750
Flights from Burlington Municipal Airport to Blue Grass Airport via Chicago O'Hare International Airport, Charlotte
- Ave. Duration
- 7h 51m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $190–950
Flights from Peoria International Airport to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $110–750
Flights from Peoria International Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 1m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $170–900
Flights from Peoria International Airport to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $240–1,200
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $90–600
Flights from Dubuque Regional Airport to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 3h 51m
- When
- Wednesday
- Estimated price
- $140–850
- Website
- united.com
Flights from Quad City International Airport to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $120–750
Flights from The Eastern Iowa Airport to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $150–950
Flights from Burlington Municipal Airport to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 3h 41m
- When
- Saturday
- Estimated price
- $120–750
Flights from Peoria International Airport to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $110–750
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $90–600
Flights from Dubuque Regional Airport to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h
- When
- Sunday
- Estimated price
- $140–850
- Website
- delta.com
Flights from Quad City International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $170–900
Flights from The Eastern Iowa Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $230–1,200
Flights from Burlington Municipal Airport to Blue Grass Airport via Chicago O'Hare International Airport, Atlanta
- Ave. Duration
- 6h 44m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Burlington Municipal Airport to Blue Grass Airport via Chicago O'Hare International Airport, Detroit
- Ave. Duration
- 7h 22m
- When
- Monday, Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $150–850
Flights from Dubuque Regional Airport to Blue Grass Airport via Chicago O'Hare International Airport, Atlanta
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $220–1,200
- Website
- southwest.com
Flights from Chicago Midway International Airport to Louisville International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $70–470
- Website
- allegiantair.com
Flights from Peoria International Airport to Blue Grass Airport via Orlando Sanford
- Ave. Duration
- 5h 23m
- When
- Thursday
- Estimated price
- $260–1,200
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $20–70
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $30–60
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 312-322-6777
- Website
- metra.com
Train from Naperville to Chicago Union Station
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- $3–6
- Website
- https://metra.com
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Muscatine, IA to Burlington, IA
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $25–50
- Website
- https://burlingtontrailways.com
- Saver Fares
- $25–40
- Flexible Fares
- $30–50
Bus from Burlington to Indianapolis Union Station
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://burlingtontrailways.com
- Saver Fares
- $60–90
- Flexible Fares
- $80–120
Bus from Burlington to Galesburg
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $25–50
- Website
- https://burlingtontrailways.com
- Saver Fares
- $25–40
- Flexible Fares
- $30–50
Bus from Muscatine to Davenport
- Ave. Duration
- 30 min
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://burlingtontrailways.com
- Saver Fares
- $22–35
- Flexible Fares
- $29–45
Bus from Davenport to Cedar Rapids Airport
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $29–55
- Website
- https://burlingtontrailways.com
- Saver Fares
- $29–45
- Flexible Fares
- $35–55
Bus from Davenport to Naperville Amtrak
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $35–75
- Website
- https://burlingtontrailways.com
- Saver Fares
- $35–55
- Flexible Fares
- $50–75
Bus from Burlington to Peoria
- Ave. Duration
- 1h 55m
- Frequency
- Once daily
- Estimated price
- $30–60
- Website
- https://burlingtontrailways.com
- Saver Fares
- $30–45
- Flexible Fares
- $40–60
Bus from Muscatine to Dubuque Intermodal Transportation Center
- Ave. Duration
- 2h
- Frequency
- 3 times a week
- Estimated price
- $30–65
- Website
- https://burlingtontrailways.com
- Saver Fares
- $30–50
- Flexible Fares
- $40–65
- Save Fare
- $45
- Flex Fare
- $58
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Indianapolis Union Station to Lexington Bus Stop
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $29–75
- Website
- https://www.greyhound.com/
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