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How to get fromMuscatine to Chicagoby car, train, taxi, bus or plane

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There are 6 ways to get from Muscatine to Chicago by car, train, taxi, bus, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, train (Amtrak)

    best
    1. Drive from Muscatine to Galesburg Amtrak Stationcar car
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train Carl Sandburg / ...
    4h 31m
    $33–89
  2. Taxi, bus (Greyhound)

    1. Take the taxi from Muscatine to Moline Center Stationtaxi taxi
    2. Take the bus from Moline Center Station to Chicago Bus Stationbus bus Greyhound US0155S / ...
    4h 59m
    $104–138
  3. Drive 199.5 mi

    1. Drive from Muscatine to Chicagocar car 199.5 mi
    3h 35m
    $37–53
  4. Taxi to Quad City International Airport, fly

    1. Take the taxi from Muscatine to Moline-Airport-MLItaxi taxi
    2. Fly from Quad City International Airport (MLI) to Chicago O'Hare International Airport (ORD)plane plane MLI - ORD
    2h 45m
    $105–312
  5. Taxi to Burlington Municipal Airport, fly

    1. Take the taxi from Muscatine to Burlington Municipal Airport (BRL)taxi taxi
    2. Fly from Burlington Municipal Airport (BRL) to Chicago O'Hare International Airport (ORD)plane plane BRL - ORD
    3h 7m
    $163–268
  6. Drive to The Eastern Iowa Airport, fly

    1. Drive from Muscatine to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Chicago O'Hare International Airport (ORD)plane plane CID - ORD
    3h 32m
    $43–250

Quad City International Airport (MLI) to Chicago O'Hare International Airport (ORD) flights

Calendar41Weekly Planes
Duration1h 16mAverage Duration
Ticket$29Cheapest Price
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Questions & Answers

What companies run services between Muscatine, IA, USA and Chicago, IL, USA?

There is no direct connection from Muscatine to Chicago. However, you can drive to Galesburg Amtrak Station then take the train to Chicago Union Station. Alternatively, you can take the taxi to Moline Center Station then take the bus to Chicago Bus Station.

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Need to know: Greyhound

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