There are 7 ways to get from Murrells Inlet to Roanoke by plane, bus, train, car, or bus (Greyhound, Flixbus, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Roanoke Regional Airport-Woodrum Field
best- Fly from Myrtle Beach (MYR) to Roanoke Regional Airport-Woodrum Field (ROA)plane MYR - ROA
4h 45m$91–355Drive 297.3 mi
cheapest- Drive from Murrells Inlet to Roanokecar 297.3 mi
6h 27m$55–79Bus, train via Fayetteville
- Take the bus from Myrtle Beach, SC to Florencebus
- Take the bus from Florence Bus Station to Fayetteville Bus Stationbus
- Take the bus from Fayetteville to High Point Terminalbus
- Take the train from High Point to Lynchburgtrain
- Take the train from Lynchburg to Roanoketrain
13h 49m$167–868Drive, train (Amtrak)
- Drive from Murrells Inlet to Kingstree Stationcar
- Take the train from Kingstree Station to Selma Stationtrain
- Take the train from Selma Station to Greensborotrain
- Take the train from Greensboro to Lynchburgtrain
- Take the train from Lynchburg to Roanoketrain
14h 21m$102–462Fly to Greenbrier Valley Airport, drive
- Fly from Myrtle Beach (MYR) to Greenbrier Valley Airport (LWB)plane MYR - LWB
- Drive from Greenbrier Valley Airport (LWB) to Roanokecar
5h 33m$124–499Bus, train
- Take the bus from Myrtle Beach, SC to Charlotte Bus Stationbus
- Take the train from Charlotte Amtrak Station to Lynchburgtrain
- Take the train from Lynchburg to Roanoketrain
14h 32m$169–699Bus
- Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus
- Take the bus from Wilmington Cape Fear Public Transit to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Richmondbus
- Take the bus from Richmond Main Street Amtrak Station to Charlottesville Amtrak Stationbus
- Take the bus from Charlottesville Union Station to Roanoke Bus Stopbus
15h 56m
Myrtle Beach (MYR) to Roanoke Regional Airport-Woodrum Field (ROA) flights
Questions & Answers
The cheapest way to get from Murrells Inlet to Roanoke is to drive which costs $50 - $80 and takes 6h 27m.
The fastest way to get from Murrells Inlet to Roanoke is to fly which takes 4h 45m and costs $90 - $360.
The distance between Murrells Inlet and Roanoke is 280 miles. The road distance is 299 miles.
The best way to get from Murrells Inlet to Roanoke without a car is to bus and train via Fayetteville which takes 13h 49m and costs $160 - $900.
It takes approximately 4h 45m to get from Murrells Inlet to Roanoke, including transfers.
The best way to get from Murrells Inlet to Roanoke is to fly which takes 4h 45m and costs $90 - $360. Alternatively, you can bus, which costs and takes 15h 56m.
Yes, the driving distance between Murrells Inlet to Roanoke is 299 miles. It takes approximately 6h 27m to drive from Murrells Inlet to Roanoke.
There are 84+ hotels available in Roanoke.
What companies run services between Murrells Inlet, SC, USA and Roanoke, VA, USA?
American Airlines, Delta, and United Airlines fly from Myrtle Beach (MYR) to Roanoke Regional Airport-Woodrum Field (ROA) every 3 hours. Alternatively, you can take a vehicle from Murrells Inlet to Roanoke Bus Stop via Myrtle Beach Bus Station, Wilmington Cape Fear Public Transit, Raleigh Bus Station, Richmond Main Street Amtrak Station, Charlottesville Amtrak Station, and Charlottesville Union Station in around 15h 56m.
- Website
- aa.com
Flights from Myrtle Beach to Roanoke Regional Airport-Woodrum Field via Charlotte
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $45–300
Flights from Myrtle Beach to Greenbrier Valley Airport via Charlotte
- Ave. Duration
- 3h 30m
- When
- Tuesday and Wednesday
- Estimated price
- $70–430
- Website
- delta.com
Flights from Myrtle Beach to Roanoke Regional Airport-Woodrum Field via Atlanta
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $65–360
- Website
- contouraviation.com
Flights from Myrtle Beach to Greenbrier Valley Airport via Charlotte
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $100–470
- Website
- united.com
Flights from Myrtle Beach to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 5h 56m
- When
- Every day
- Estimated price
- $100–470
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from High Point to Lynchburg
- Ave. Duration
- 2h 36m
- Frequency
- Once daily
- Estimated price
- $45–390
- Website
- https://www.amtrak.com/home.html
Train from Kingstree Station to Selma Station
- Ave. Duration
- 2h 59m
- Frequency
- Once daily
- Estimated price
- $21–90
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $25–45
- Coach Seat short notice purchase
- $21–90
- Business - advance purchase
- $29–160
- Business Class
- $50–230
Train from Selma Station to Greensboro
- Ave. Duration
- 3h 24m
- Frequency
- Once daily
- Estimated price
- $23–55
- Website
- https://www.amtrak.com/home.html
Train from Greensboro to Lynchburg
- Ave. Duration
- 2h 8m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- https://www.amtrak.com/home.html
Train from Charlotte Amtrak Station to Lynchburg
- Ave. Duration
- 4h 6m
- Frequency
- Once daily
- Estimated price
- $55–320
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Lynchburg to Roanoke
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- $7–210
- Website
- https://www.amtrak.com/home
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $7–210
- Business Class
- $50–240
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Myrtle Beach, SC to Florence
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $25–95
- Schedules at
- southeasternstages.com
Bus from Florence Bus Station to Fayetteville Bus Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $29–95
- Schedules at
- southeasternstages.com
Bus from Myrtle Beach, SC to Charlotte Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- southeasternstages.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Myrtle Beach, SC to Florence
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $26–55
- Website
- https://www.greyhound.com/
Bus from Florence Bus Station to Fayetteville Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $28–60
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transit
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $17–21
- Website
- https://www.greyhound.com/
Bus from Wilmington Cape Fear Public Transit to Raleigh Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- $24–40
- Website
- https://www.greyhound.com/
Bus from Raleigh Bus Station to Richmond
- Ave. Duration
- 2h 35m
- Frequency
- Every 4 hours
- Estimated price
- $29–55
- Website
- https://www.greyhound.com/
Bus from Charlottesville Union Station to Roanoke Bus Stop
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $22–35
- Website
- https://www.greyhound.com/
- Phone
- +1 704-348-1200
- info@sunwaycharters.com
- Website
- sunwaycharters.com
Bus from Fayetteville to High Point Terminal
- Ave. Duration
- 2h 36m
- Frequency
- Once daily
- Estimated price
- $17–25
- Schedules at
- sunwaycharters.com
- Passenger
- $17–25
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Raleigh Bus Station to Richmond
- Ave. Duration
- 3h 10m
- Frequency
- 3 times a day
- Estimated price
- $27–45
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Richmond Main Street Amtrak Station to Charlottesville Amtrak Station
- Ave. Duration
- 2h
- Frequency
- 6 times a week
- Website
- https://www.amtrak.com/home.html
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