There are 5 ways to get from Murrells Inlet to Roanoke by plane, bus, train, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Myrtle Beach (MYR) to Roanoke Regional Airport-Woodrum Field (ROA)plane MYR - ROA
4h 35m$90–363Drive 297.3 mi
cheapest- Drive from Murrells Inlet to Roanokecar 297.3 mi
6h 27m$55–79Bus, train
- Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus
- Take the bus from Fayetteville to High Pointbus
- Take the train from High Point to Lynchburgtrain
- Take the train from Lynchburg to Roanoketrain
12h 48m$187–275Drive, train (Amtrak)
- Drive from Murrells Inlet to Kingstree Stationcar
- Take the train from Kingstree Station to Selma Stationtrain
- Take the train from Selma Station to Greensborotrain
- Take the train from Greensboro to Lynchburgtrain
- Take the train from Lynchburg to Roanoketrain
13h 31m$249–402Bus
- Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Greensboro Bus Stopbus
- Take the bus from Greensboro Bus Stop to Lynchburg Transit Centerbus
- Take the bus from Lynchburg Transit Center to Roanoke Bus Stopbus
14h$121–180
Myrtle Beach (MYR) to Roanoke Regional Airport-Woodrum Field (ROA) flights
Comparing Your Travel Options
The cheapest way to get from Murrells Inlet to Roanoke is to drive which costs $50 - $80 and takes 6h 27m.
The fastest way to get from Murrells Inlet to Roanoke is to fly which takes 4h 35m and costs $90 - $370.
No, there is no direct bus from Murrells Inlet station to Roanoke. However, there are services departing from Myrtle Beach Bus Station and arriving at Roanoke Bus Stop via Raleigh Bus Station, Greensboro Bus Stop and Lynchburg Transit Center. The journey, including transfers, takes approximately 14h.
The distance between Murrells Inlet and Roanoke is 280 miles. The road distance is 299 miles.
The best way to get from Murrells Inlet to Roanoke without a car is to bus and train which takes 12h 48m and costs $180 - $280.
It takes approximately 4h 35m to get from Murrells Inlet to Roanoke, including transfers.
Murrells Inlet to Roanoke bus services, operated by Greyhound USA, depart from Myrtle Beach Bus Station.
The best way to get from Murrells Inlet to Roanoke is to fly which takes 4h 35m and costs $90 - $370. Alternatively, you can bus, which costs $120 - $180 and takes 14h.
Murrells Inlet to Roanoke bus services, operated by Greyhound USA, arrive at Raleigh Bus Station.
Yes, the driving distance between Murrells Inlet to Roanoke is 299 miles. It takes approximately 6h 27m to drive from Murrells Inlet to Roanoke.
What companies run services between Murrells Inlet, SC, USA and Roanoke, VA, USA?
American Airlines, United Airlines, and Delta fly from Myrtle Beach (MYR) to Roanoke Regional Airport-Woodrum Field (ROA) every 2 hours. Alternatively, you can take a vehicle from Murrells Inlet to Roanoke Bus Stop via Myrtle Beach Bus Station, Raleigh Bus Station, Greensboro Bus Stop, and Lynchburg Transit Center in around 14h.
- Website
- aa.com
Flights from Myrtle Beach to Roanoke Regional Airport-Woodrum Field via Charlotte
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $45–310
Flights from Myrtle Beach to Roanoke Regional Airport-Woodrum Field via Philadelphia
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $75–400
Flights from Myrtle Beach to Roanoke Regional Airport-Woodrum Field via New York La Guardia
- Ave. Duration
- 6h 43m
- When
- Saturday
- Estimated price
- $85–430
- Website
- delta.com
Flights from Myrtle Beach to Roanoke Regional Airport-Woodrum Field via Atlanta
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $65–380
Flights from Myrtle Beach to Roanoke Regional Airport-Woodrum Field via New York La Guardia
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $85–430
- Website
- united.com
Flights from Myrtle Beach to Roanoke Regional Airport-Woodrum Field via Washington Dulles
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $60–350
Flights from Myrtle Beach to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 6h 15m
- When
- Monday to Saturday
- Estimated price
- $100–480
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from High Point to Lynchburg
- Ave. Duration
- 2h 36m
- Frequency
- Once daily
- Estimated price
- $70–110
- Website
- Amtrak
Train from Lynchburg to Roanoke
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- $28–45
- Website
- Amtrak
Train from Kingstree Station to Selma Station
- Ave. Duration
- 2h 59m
- Frequency
- Once daily
- Estimated price
- $90–150
- Website
- Amtrak
Train from Selma Station to Greensboro
- Ave. Duration
- 2h 34m
- Frequency
- Once daily
- Estimated price
- $60–95
- Website
- Amtrak
Train from Greensboro to Lynchburg
- Ave. Duration
- 2h 8m
- Frequency
- Once daily
- Estimated price
- $60–95
- Website
- Amtrak
Train from Lynchburg to Roanoke
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- $28–45
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Fayetteville Bus Station
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $27–40
- Website
- Greyhound
Bus from Fayetteville to High Point
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $19–29
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Raleigh Bus Station
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Raleigh Bus Station to Greensboro Bus Stop
- Ave. Duration
- 1h 35m
- Frequency
- 5 times a day
- Estimated price
- $13–20
- Website
- Greyhound
Bus from Lynchburg Transit Center to Roanoke Bus Stop
- Ave. Duration
- 1h 9m
- Frequency
- Once daily
- Estimated price
- $9–14
- Website
- Greyhound
- Phone
- +1 704-348-1200
- info@sunwaycharters.com
- Website
- Sunway Charters
Bus from Fayetteville to High Point
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $17–25
- Schedules at
- Sunway Charters
- Passenger
- $17–25
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Raleigh Bus Station to Greensboro Bus Stop
- Ave. Duration
- 1h 35m
- Frequency
- 5 times a week
- Estimated price
- $11–18
- Schedules at
- Flixbus USA
Bus from Greensboro Bus Stop to Lynchburg Transit Center
- Ave. Duration
- 3h 35m
- Frequency
- 4 times a week
- Estimated price
- $23–35
- Schedules at
- Flixbus USA
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Booking & Getting There
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