There are 7 ways to get from Murrells Inlet to Roanoke by plane, bus, train, car, or bus (Greyhound, Flixbus, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Roanoke Regional Airport-Woodrum Field
best- Fly from Myrtle Beach (MYR) to Roanoke Regional Airport-Woodrum Field (ROA)MYR - ROA
4h 54m$91–355Drive 297.3 mi
cheapest- Drive from Murrells Inlet to Roanoke297.3 mi
6h 25m$55–79Bus, train via Fayetteville
- Take the bus from Myrtle Beach, SC to Florence
- Take the bus from Florence Bus Station to Fayetteville Bus Station
- Take the bus from Fayetteville to High Point Terminal
- Take the train from High Point to Lynchburg
- Take the train from Lynchburg to Roanoke
13h 49m$138–553Drive, train (Amtrak)
- Drive from Murrells Inlet to Kingstree Amtrak Station
- Take the train from Kingstree Amtrak Station to Selma
- Take the train from Selma to Greensboro
- Take the train from Greensboro to Lynchburg
- Take the train from Lynchburg to Roanoke
14h 20m$88–447Fly to Greenbrier Valley Airport, drive
- Fly from Myrtle Beach (MYR) to Greenbrier Valley Airport (LWB)MYR - LWB
- Drive from Greenbrier Valley Airport (LWB) to Roanoke
6h 23m$114–459Bus, train
- Take the bus from Myrtle Beach, SC to Charlotte Bus Station
- Take the train from Charlotte Amtrak Station to Lynchburg
- Take the train from Lynchburg to Roanoke
14h 19m$169–479Bus
- Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transit
- Take the bus from Wilmington Cape Fear Public Transit to Raleigh Bus Station
- Take the bus from Raleigh Bus Station to Richmond
- Take the bus from Richmond Main Street Amtrak Station to Charlottesville Amtrak Station
- Take the bus from Charlottesville Union Station to Roanoke Bus Stop
15h 56m
Myrtle Beach (MYR) to Roanoke Regional Airport-Woodrum Field (ROA) flights
Questions & Answers
The cheapest way to get from Murrells Inlet to Roanoke is to drive which costs $50 - $80 and takes 6h 25m.
The fastest way to get from Murrells Inlet to Roanoke is to fly which takes 4h 54m and costs $90 - $360.
The distance between Murrells Inlet and Roanoke is 280 miles. The road distance is 299 miles.
The best way to get from Murrells Inlet to Roanoke without a car is to bus and train via Fayetteville which takes 13h 49m and costs $130 - $600.
It takes approximately 4h 54m to get from Murrells Inlet to Roanoke, including transfers.
The best way to get from Murrells Inlet to Roanoke is to fly which takes 4h 54m and costs $90 - $360. Alternatively, you can bus, which costs and takes 15h 56m.
Yes, the driving distance between Murrells Inlet to Roanoke is 299 miles. It takes approximately 6h 25m to drive from Murrells Inlet to Roanoke.
There are 81+ hotels available in Roanoke.
What companies run services between Murrells Inlet, SC, USA and Roanoke, VA, USA?
American Airlines and Delta fly from Myrtle Beach (MYR) to Roanoke Regional Airport-Woodrum Field (ROA) every 3 hours. Alternatively, you can take a vehicle from Murrells Inlet to Roanoke Bus Stop via Myrtle Beach Bus Station, Wilmington Cape Fear Public Transit, Raleigh Bus Station, Richmond Main Street Amtrak Station, Charlottesville Amtrak Station, and Charlottesville Union Station in around 15h 56m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Myrtle Beach to Roanoke Regional Airport-Woodrum Field via Charlotte
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $45–300
Flights from Myrtle Beach to Roanoke Regional Airport-Woodrum Field via Philadelphia
- Ave. Duration
- 5h 1m
- When
- Thursday
- Estimated price
- $70–380
Flights from Myrtle Beach to Roanoke Regional Airport-Woodrum Field via New York La Guardia
- Ave. Duration
- 6h 26m
- When
- Saturday
- Estimated price
- $80–410
Flights from Myrtle Beach to Greenbrier Valley Airport via Charlotte
- Ave. Duration
- 4h 48m
- When
- Tuesday and Wednesday
- Estimated price
- $60–390
- Website
- delta.com
Flights from Myrtle Beach to Roanoke Regional Airport-Woodrum Field via Atlanta
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $65–360
- Website
- contouraviation.com
Flights from Myrtle Beach to Greenbrier Valley Airport via Charlotte
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $110–420
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from High Point to Lynchburg
- Ave. Duration
- 2h 36m
- Frequency
- Once daily
- Estimated price
- $16–75
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $21–35
- Coach Seat short notice purchase
- $16–75
- Business - advance purchase
- $22–130
- Business Class
- $35–200
Train from Kingstree Amtrak Station to Selma
- Ave. Duration
- 2h 59m
- Frequency
- Once daily
- Estimated price
- $21–90
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $25–45
- Coach Seat short notice purchase
- $21–90
- Business - advance purchase
- $29–160
- Business Class
- $50–230
Train from Selma to Greensboro
- Ave. Duration
- 3h 24m
- Frequency
- Once daily
- Estimated price
- $14–75
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $20–35
- Coach Seat short notice purchase
- $14–75
- Business - advance purchase
- $19–120
- Business Class
- $30–190
Train from Greensboro to Lynchburg
- Ave. Duration
- 2h 8m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://www.amtrak.com/home.html
Train from Charlotte Amtrak Station to Lynchburg
- Ave. Duration
- 4h 6m
- Frequency
- Once daily
- Estimated price
- $55–100
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Lynchburg to Roanoke
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- $7–210
- Website
- https://www.amtrak.com/home.html
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $7–210
- Business Class
- $50–240
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Myrtle Beach, SC to Florence
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $25–95
- Schedules at
- southeasternstages.com
Bus from Florence Bus Station to Fayetteville Bus Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $29–95
- Schedules at
- southeasternstages.com
Bus from Myrtle Beach, SC to Charlotte Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- southeasternstages.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Myrtle Beach, SC to Florence
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $26–55
- Website
- https://www.greyhound.com/
Bus from Florence Bus Station to Fayetteville Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $28–60
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transit
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $17–24
- Website
- https://www.greyhound.com/
Bus from Wilmington Cape Fear Public Transit to Raleigh Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- $26–45
- Website
- https://www.greyhound.com/
Bus from Raleigh Bus Station to Richmond
- Ave. Duration
- 2h 35m
- Frequency
- Every 4 hours
- Estimated price
- $30–55
- Website
- https://www.greyhound.com/
Bus from Charlottesville Union Station to Roanoke Bus Stop
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $25–35
- Website
- https://www.greyhound.com/
- Phone
- +1 704-348-1200
- info@sunwaycharters.com
- Website
- sunwaycharters.com
Bus from Fayetteville to High Point Terminal
- Ave. Duration
- 2h 36m
- Frequency
- Once daily
- Estimated price
- $17–25
- Schedules at
- sunwaycharters.com
- Passenger
- $17–25
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Raleigh Bus Station to Richmond
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- $28–45
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Richmond Main Street Amtrak Station to Charlottesville Amtrak Station
- Ave. Duration
- 2h
- Frequency
- 3 times a week
- Website
- https://www.amtrak.com/home.html
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