What is the cheapest way to get from Murrells Inlet to Knoxville?

The cheapest way to get from Murrells Inlet to Knoxville is to drive which costs $70 - $110 and takes 7h 49m.

What is the fastest way to get from Murrells Inlet to Knoxville?

The fastest way to get from Murrells Inlet to Knoxville is to fly which takes 3h 49m and costs $180 - $750.

How far is it from Murrells Inlet to Knoxville?

The distance between Murrells Inlet and Knoxville is 351 miles. The road distance is 411.9 miles.

How long does it take to get from Murrells Inlet to Knoxville?

It takes approximately 3h 49m to get from Murrells Inlet to Knoxville, including transfers.

Can I drive from Murrells Inlet to Knoxville?

Yes, the driving distance between Murrells Inlet to Knoxville is 412 miles. It takes approximately 7h 49m to drive from Murrells Inlet to Knoxville.

Where can I stay near Knoxville?

There are 315+ hotels available in Knoxville.

Murrells Inlet to Knoxville - 3 ways to travel via plane, bus, shuttle, and car

How to get fromMurrells Inlet to Knoxville

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There are 3 ways to get from Murrells Inlet to Knoxville by plane, bus, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly
best
1. Fly from Myrtle Beach (MYR) to Mcghee Tyson Airport (TYS)plane MYR - TYS
3h 49m
$181–718
Drive 409.6 mi
cheapest
1. Drive from Murrells Inlet to Knoxvillecar 409.6 mi
7h 49m
$75–108
Bus, shuttle, drive
1. Take the bus from Myrtle Beach Bus Station to Camdenbus
2. Take the bus from Camden to Charlotte Bus Stationbus
3. Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus
4. Take a shuttle bus from Boone to Black Bear Resortshuttle
5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle
6. Drive from Hot Springs to Knoxvillecar
15h 6m
$425–499

Myrtle Beach (MYR) to Mcghee Tyson Airport (TYS) flights

74Weekly Planes

4h 23mAverage Duration

$88Cheapest Price

See schedules

Questions & Answers

Map of how to get from Murrells Inlet to Knoxville.

Launch map view

Distance: 348.8 mi
Duration: 3h 49m

What companies run services between Murrells Inlet, SC, USA and Knoxville, TN, USA?

Delta, American Airlines, and Southwest Airlines fly from Myrtle Beach (MYR) to Mcghee Tyson Airport (TYS) every 2 hours.

Airlines

Bus operators

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How to get fromMurrells Inlet to Knoxvilleby plane, bus, shuttle, or car

There are 3 ways to get from Murrells Inlet to Knoxville by plane, bus, shuttle, or car

Fly

Drive 409.6 mi

Bus, shuttle, drive