What is the cheapest way to get from Murrells Inlet to Knoxville?

The cheapest way to get from Murrells Inlet to Knoxville is to drive which costs $70 - $110 and takes 7h 49m.

What is the fastest way to get from Murrells Inlet to Knoxville?

The fastest way to get from Murrells Inlet to Knoxville is to fly which takes 3h 58m and costs $190 - $850.

How far is it from Murrells Inlet to Knoxville?

The distance between Murrells Inlet and Knoxville is 351 miles. The road distance is 411.9 miles.

How long does it take to get from Murrells Inlet to Knoxville?

It takes approximately 3h 58m to get from Murrells Inlet to Knoxville, including transfers.

Can I drive from Murrells Inlet to Knoxville?

Yes, the driving distance between Murrells Inlet to Knoxville is 412 miles. It takes approximately 7h 49m to drive from Murrells Inlet to Knoxville.

Where can I stay near Knoxville?

There are 292+ hotels available in Knoxville.

Murrells Inlet to Knoxville - 3 ways to travel via plane, bus, shuttle, and car

There are 3 ways to get from Murrells Inlet to Knoxville by plane, bus, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly
best
1. Fly from Myrtle Beach (MYR) to Mcghee Tyson Airport (TYS)plane MYR - TYS
3h 58m
$192–820
Drive 409.6 mi
cheapest
1. Drive from Murrells Inlet to Knoxvillecar 409.6 mi
7h 49m
$75–108
Bus, shuttle, drive
1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus
2. Take the bus from Wilmington Cape Fear Public Transit to Charlotte Bus Stationbus
3. Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus
4. Take a shuttle bus from Boone to Black Bear Resortshuttle
5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle
6. Drive from Hot Springs to Knoxvillecar
18h 7m
$452–554

Myrtle Beach (MYR) to Mcghee Tyson Airport (TYS) flights

59Weekly Planes

4h 37mAverage Duration

$99Cheapest Price

See schedules

Questions & Answers

Map of how to get from Murrells Inlet to Knoxville.

Launch map view

Distance: 348.8 mi
Duration: 3h 58m

What companies run services between Murrells Inlet, SC, USA and Knoxville, TN, USA?

Delta, American Airlines, and Southwest Airlines fly from Myrtle Beach (MYR) to Mcghee Tyson Airport (TYS) every 4 hours.

Airlines

Bus operators

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