What is the cheapest way to get from Murrells Inlet to Knoxville?

The cheapest way to get from Murrells Inlet to Knoxville is to drive which costs $70 - $110 and takes 7h 46m.

What is the fastest way to get from Murrells Inlet to Knoxville?

The fastest way to get from Murrells Inlet to Knoxville is to fly which takes 3h 57m and costs $180 - $700.

How far is it from Murrells Inlet to Knoxville?

The distance between Murrells Inlet and Knoxville is 351 miles. The road distance is 411.9 miles.

How long does it take to get from Murrells Inlet to Knoxville?

It takes approximately 3h 57m to get from Murrells Inlet to Knoxville, including transfers.

Can I drive from Murrells Inlet to Knoxville?

Yes, the driving distance between Murrells Inlet to Knoxville is 412 miles. It takes approximately 7h 46m to drive from Murrells Inlet to Knoxville.

Where can I stay near Knoxville?

There are 272+ hotels available in Knoxville.

Murrells Inlet to Knoxville - 4 ways to travel via plane, bus, shuttle, and car

There are 4 ways to get from Murrells Inlet to Knoxville by plane, bus, shuttle, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly
best
1. Fly from Myrtle Beach (MYR) to Mcghee Tyson Airport (TYS)MYR - TYS
3h 57m
$182–670
Drive 409.5 mi
cheapest
1. Drive from Murrells Inlet to Knoxville409.5 mi
7h 46m
$75–108
Bus, shuttle, drive
1. Take the bus from Myrtle Beach, SC to Charlotte Bus Station
2. Take the bus from Charlotte Airport to ASU Peacock Hall Boone
3. Take a shuttle bus from Boone to Black Bear Resort
4. Take a shuttle bus from Black Bear Resort to Hot Springs, NC
5. Drive from Hot Springs, NC to Knoxville
15h 44m
$443–533
Bus, taxi, shuttle, drive
1. Take the bus from Myrtle Beach, SC to Charlotte Bus Station
2. Take the bus from Charlotte Airport to ASU Peacock Hall Boone
3. Take the taxi from ASU Peacock Hall Boone to Black Bear Resort
4. Take a shuttle bus from Black Bear Resort to Hot Springs, NC
5. Drive from Hot Springs, NC to Chilhowee at Holston
16h 32m
$444–556

Myrtle Beach (MYR) to Mcghee Tyson Airport (TYS) flights

77Weekly Planes

4h 13mAverage Duration

$85Cheapest Price

See schedules

Questions & Answers

Map of how to get from Murrells Inlet to Knoxville.

Launch map view

Distance: 348.8 mi
Duration: 3h 57m

What companies run services between Murrells Inlet, SC, USA and Knoxville, TN, USA?

American Airlines and Delta fly from Myrtle Beach (MYR) to Mcghee Tyson Airport (TYS) every 2 hours.

Airlines

Bus operators

Other operators

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