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How to get fromMurrells Inlet to Key Westby plane, car, train, bus, bus (Greyhound, Flixbus) or shuttle

Find Transport to Key West

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There are 5 ways to get from Murrells Inlet to Key West by plane, car, train, bus, bus (Greyhound, Flixbus), or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Myrtle Beach (MYR) to Key West International Airport (EYW)plane plane MYR - EYW
    5h 3m
    $153–613

  2. Drive, train, bus

    cheapest
    1. Drive from Murrells Inlet to Kingstree Stationcar car
    2. Take the train from Kingstree Station to Hollywood Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    23h 58m
    $104–282

  3. Bus

    1. Take the bus from Myrtle Beach, SC to Florencebus bus
    2. Take the bus from Florence Bus Station to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    24h 13m
    $183–417

  4. Drive 821 mi

    1. Drive from Murrells Inlet to Key Westcar car 821 mi
    15h 2m
    $150–217

  5. Bus, train, shuttle

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Miami Amtrak Stationtrain train
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    24h 58m
    $294–467

Myrtle Beach (MYR) to Key West International Airport (EYW) flights

Calendar49Weekly Planes
Duration5h 44mAverage Duration
Ticket$103Cheapest Price
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Questions & Answers

What companies run services between Murrells Inlet, SC, USA and Key West, FL, USA?

American Airlines and Delta fly from Myrtle Beach (MYR) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a vehicle from Murrells Inlet to N Roosevelt & 3rd Street via Myrtle Beach, SC, Florence, Florence Bus Station, Orlando Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 24h 13m.

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