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How to get fromMurrells Inlet to Key Westby plane, car, train, bus, bus (Greyhound, Flixbus) or shuttle

Find Transport to Key West

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There are 5 ways to get from Murrells Inlet to Key West by plane, car, train, bus, bus (Greyhound, Flixbus), or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Myrtle Beach (MYR) to Key West International Airport (EYW)planeMYR - EYW
    5h 38m
    $138–503

  2. Drive, train, bus

    cheapest
    1. Drive from Murrells Inlet to Kingstree Amtrak Stationcar
    2. Take the train from Kingstree Amtrak Station to Hollywood Amtrak Stationtrain
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    23h 57m
    $102–282

  3. Bus

    1. Take the bus from Myrtle Beach, SC to Florencebus
    2. Take the bus from Florence Bus Station to Orlando Bus Stationbus
    3. Take the bus from Orlando Bus Station to Miami Airport Stationbus
    4. Take the bus from Miami Airport Station to Big Pine Keybus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    24h 12m
    $191–427

  4. Drive 821 mi

    1. Drive from Murrells Inlet to Key Westcar821 mi
    14h 53m
    $150–217

  5. Bus, train, shuttle

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
    2. Take the train from Charleston Amtrak Station to Miami Amtrak Stationtrain
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle
    24h 58m
    $309–526

Myrtle Beach (MYR) to Key West International Airport (EYW) flights

Calendar45Weekly Planes
Duration5h 55mAverage Duration
Ticket$87Cheapest Price
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Questions & Answers

What companies run services between Murrells Inlet, SC, USA and Key West, FL, USA?

Delta and American Airlines fly from Myrtle Beach (MYR) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a vehicle from Murrells Inlet to N Roosevelt & 3rd Street via Myrtle Beach, SC, Florence, Florence Bus Station, Orlando Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 24h 12m.

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