There are 5 ways to get from Murrells Inlet to Key West by plane, car, train, bus, bus (Greyhound, Flixbus), or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Myrtle Beach (MYR) to Key West International Airport (EYW)plane MYR - EYW
3h 59m$153–613Drive, train, bus
cheapest- Drive from Murrells Inlet to Kingstree Stationcar
- Take the train from Kingstree Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
23h 58m$102–277Bus
- Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
30h 38m$173–357Drive 821 mi
- Drive from Murrells Inlet to Key Westcar 821 mi
15h 1m$150–217Bus, train, shuttle
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
- Take the train from Charleston Amtrak Station to Miami Amtrak Stationtrain
- Take a shuttle bus from Miami, FL - International Airport to Key West, FL
24h 58m$315–446
Myrtle Beach (MYR) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Murrells Inlet to Key West is to drive which costs $150 - $220 and takes 15h 1m.
The fastest way to get from Murrells Inlet to Key West is to fly which takes 3h 59m and costs $150 - $650.
The distance between Murrells Inlet and Key West is 672 miles. The road distance is 825.8 miles.
The best way to get from Murrells Inlet to Key West without a car is to bus which takes 30h 38m and costs $170 - $360.
It takes approximately 3h 59m to get from Murrells Inlet to Key West, including transfers.
The best way to get from Murrells Inlet to Key West is to fly which takes 3h 59m and costs $150 - $650. Alternatively, you can bus, which costs $170 - $360 and takes 30h 38m.
Yes, the driving distance between Murrells Inlet to Key West is 826 miles. It takes approximately 15h 1m to drive from Murrells Inlet to Key West.
There are 806+ hotels available in Key West.
What companies run services between Murrells Inlet, SC, USA and Key West, FL, USA?
Spirit Airlines, American Airlines, and Delta fly from Myrtle Beach (MYR) to Key West International Airport (EYW) 5 times a day. Alternatively, you can take a vehicle from Murrells Inlet to N Roosevelt & 3rd Street via Myrtle Beach Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 30h 38m.
- Website
- aa.com
Flights from Myrtle Beach to Key West International Airport via Charlotte
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $100–550
- Website
- delta.com
Flights from Myrtle Beach to Key West International Airport via Atlanta
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $110–550
- Website
- spirit.com
Flights from Myrtle Beach to Key West International Airport via Fort Lauderdale
- Ave. Duration
- 4h 21m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Kingstree Station to Hollywood Amtrak Station
- Ave. Duration
- 14h 25m
- Frequency
- Once daily
- Estimated price
- $65–220
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $65–180
- Coach Seat short notice purchase
- $90–220
- Business - advance purchase
- $120–500
- Business Class
- $200–500
Train from Charleston Amtrak Station to Miami Amtrak Station
- Ave. Duration
- 14h 3m
- Frequency
- Once daily
- Estimated price
- $85–170
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $21–30
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Atlanta Bus Station
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Charleston Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $12–14
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 13h 30m
- Frequency
- Once daily
- Estimated price
- $55–170
- Schedules at
- flixbus.com
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key West, FL
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
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