There are 5 ways to get from Murrells Inlet to Key West by plane, car, train, bus, bus (Greyhound, Flixbus), or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Myrtle Beach (MYR) to Key West International Airport (EYW)MYR - EYW
4h 51m$143–523Drive, train, bus
cheapest- Drive from Murrells Inlet to Kingstree Station
- Take the train from Kingstree Station to Hollywood Amtrak Station
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
23h 58m$102–287Bus
- Take the bus from Myrtle Beach, SC to Florence
- Take the bus from Florence Bus Station to Orlando Bus Station
- Take the bus from Orlando Bus Station to Miami Airport Station
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
24h 13m$196–462Drive 821 mi
- Drive from Murrells Inlet to Key West821 mi
14h 53m$150–217Bus, train, shuttle
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Station
- Take the train from Charleston Amtrak Station to Miami Amtrak Station
- Take a shuttle bus from Miami, FL - International Airport to Key West, FL
24h 58m$304–557
Myrtle Beach (MYR) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Murrells Inlet to Key West is to drive which costs $150 - $220 and takes 14h 53m.
The fastest way to get from Murrells Inlet to Key West is to fly which takes 4h 51m and costs $140 - $550.
The distance between Murrells Inlet and Key West is 672 miles. The road distance is 825.8 miles.
The best way to get from Murrells Inlet to Key West without a car is to bus which takes 24h 13m and costs $190 - $470.
It takes approximately 4h 51m to get from Murrells Inlet to Key West, including transfers.
The best way to get from Murrells Inlet to Key West is to fly which takes 4h 51m and costs $140 - $550. Alternatively, you can bus, which costs $190 - $470 and takes 24h 13m.
Yes, the driving distance between Murrells Inlet to Key West is 826 miles. It takes approximately 14h 53m to drive from Murrells Inlet to Key West.
There are 869+ hotels available in Key West.
What companies run services between Murrells Inlet, SC, USA and Key West, FL, USA?
American Airlines and Delta fly from Myrtle Beach (MYR) to Key West International Airport (EYW) 4 times a day. Alternatively, you can take a vehicle from Murrells Inlet to N Roosevelt & 3rd Street via Myrtle Beach, SC, Florence, Florence Bus Station, Orlando Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 24h 13m.
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Kingstree Station to Hollywood Amtrak Station
- Ave. Duration
- 14h 25m
- Frequency
- Once daily
- Estimated price
- $65–220
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $65–180
- Coach Seat short notice purchase
- $90–220
- Business - advance purchase
- $120–500
- Business Class
- $200–500
Train from Charleston Amtrak Station to Miami Amtrak Station
- Ave. Duration
- 14h 3m
- Frequency
- Once daily
- Estimated price
- $95–280
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $21–40
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach, SC to Florence
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $26–55
- Website
- https://www.greyhound.com/
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $28–55
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Charleston Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $11–15
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Myrtle Beach, SC to Florence
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $25–95
- Schedules at
- southeasternstages.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Florence Bus Station to Orlando Bus Station
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- $75–210
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 4h 50m
- Frequency
- Hourly
- Estimated price
- $28–60
- Schedules at
- flixbus.com
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key West, FL
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $150–200
- Website
- https://www.keysshuttle.com
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