There are 6 ways to get from Murrells Inlet to Gainesville by plane, car, train, bus, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Gainesville Regional Airport
best- Fly from Myrtle Beach (MYR) to Gainesville Regional Airport (GNV)MYR - GNV
5h 20m$104–392Drive, train, bus
cheapest- Drive from Murrells Inlet to Kingstree Amtrak Station
- Take the train from Kingstree Amtrak Station to Jacksonville
- Take the bus from Jacksonville to Gainesville
10h 26m$63–161Bus
- Take the bus from Myrtle Beach, SC to Florence
- Take the bus from Florence Bus Station to Jacksonville
- Take the bus from Jacksonville to Gainesville
10h 46m$121–264Drive 381.9 mi
- Drive from Murrells Inlet to Gainesville381.9 mi
7h 11m$70–101Fly to Orlando, bus
- Fly from Myrtle Beach (MYR) to Orlando (MCO)MYR - MCO
- Take the bus from Orlando RedCoach Station to Gainesville
5h 17m$128–322Bus, train
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Station
- Take the train from Charleston Amtrak Station to Jacksonville
- Take the bus from Jacksonville to Gainesville
11h 39m$133–211
Myrtle Beach (MYR) to Gainesville Regional Airport (GNV) flights
Questions & Answers
The cheapest way to get from Murrells Inlet to Gainesville is to drive which costs $65 - $110 and takes 7h 11m.
The fastest way to get from Murrells Inlet to Gainesville is to fly and bus which takes 5h 17m and costs $120 - $330.
The distance between Murrells Inlet and Gainesville is 362 miles. The road distance is 384.2 miles.
The best way to get from Murrells Inlet to Gainesville without a car is to bus which takes 10h 46m and costs $120 - $270.
It takes approximately 5h 20m to get from Murrells Inlet to Gainesville, including transfers.
The best way to get from Murrells Inlet to Gainesville is to fly which takes 5h 20m and costs $100 - $400. Alternatively, you can bus, which costs $120 - $270 and takes 10h 46m.
Yes, the driving distance between Murrells Inlet to Gainesville is 384 miles. It takes approximately 7h 11m to drive from Murrells Inlet to Gainesville.
There are 231+ hotels available in Gainesville.
What companies run services between Murrells Inlet, SC, USA and Gainesville, FL, USA?
Delta and American Airlines fly from Myrtle Beach (MYR) to Gainesville Regional Airport (GNV) every 4 hours. Alternatively, you can take a vehicle from Murrells Inlet to Gainesville via Myrtle Beach, SC, Florence, Florence Bus Station, and Jacksonville in around 10h 46m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Myrtle Beach to Gainesville Regional Airport via Charlotte
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $60–340
Flights from Myrtle Beach to Orlando via Charlotte
- Ave. Duration
- 3h 52m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $55–320
- Website
- delta.com
Flights from Myrtle Beach to Gainesville Regional Airport via Atlanta
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $60–350
Flights from Myrtle Beach to Orlando via Atlanta
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $60–330
- Website
- spirit.com
Flights from Myrtle Beach to Orlando
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $70–200
- Website
- flybreeze.com
Flights from Myrtle Beach to Orlando
- Ave. Duration
- 1h 40m
- When
- Thursday and Sunday
- Estimated price
- $130–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Kingstree Amtrak Station to Jacksonville
- Ave. Duration
- 5h 28m
- Frequency
- Once daily
- Estimated price
- $35–120
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $35–80
- Coach Seat short notice purchase
- $35–120
- Business - advance purchase
- $50–240
- Business Class
- $85–290
Train from Charleston Amtrak Station to Jacksonville
- Ave. Duration
- 4h 28m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Jacksonville to Gainesville
- Ave. Duration
- 1h 30m
- Frequency
- 6 times a week
- Estimated price
- $16–21
- Schedules at
- flixbus.com
Bus from Florence Bus Station to Jacksonville
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Estimated price
- $35–95
- Schedules at
- flixbus.com
- Adult
- $35–95
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Myrtle Beach, SC to Florence
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $25–95
- Schedules at
- southeasternstages.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Myrtle Beach, SC to Florence
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $26–55
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Charleston Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $11–14
- Website
- https://www.greyhound.com/
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Orlando RedCoach Station to Gainesville
- Ave. Duration
- 1h 55m
- Frequency
- Every 4 hours
- Estimated price
- $14–60
- Website
- https://www.redcoachusa.com
- Web
- $14–60
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