There are 10 ways to get from Murrells Inlet to Fort Myers by plane, bus, train, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Myrtle Beach to Ft. Myers
best- Fly from Myrtle Beach (MYR) to Ft. Myers (RSW)plane MYR - RSW
7h 11m$384–603Drive 609.6 mi
cheapest- Drive from Murrells Inlet to Fort Myerscar 609.6 mi
11h 23m$112–161Bus, train via Jacksonville
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
- Take the train from Charleston Amtrak Station to Jacksonvilletrain
- Take the bus from Jacksonville to Wildwood Amtrak Stationbus
- Take the bus from Wildwood to Fort Myersbus
18h 13m$233–396Drive, train, bus
- Drive from Murrells Inlet to Kingstree Stationcar
- Take the train from Kingstree Station to Fort Lauderdale Amtrak Stationtrain
- Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus
19h 59m$230–497Fly Myrtle Beach to Tampa, bus
- Fly from Myrtle Beach (MYR) to Tampa (TPA)plane MYR - TPA
- Take the bus from Tampa International Airport to Fort Myers 7-11bus
5h 25m$164–730Fly Myrtle Beach to Orlando, bus
- Fly from Myrtle Beach (MYR) to Orlando (MCO)plane MYR - MCO
- Take the bus from Orlando to Fort Myers Bus Stopbus
8h 44m$147–440Bus to Wilmington International Airport, fly to Ft. Myers
- Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus
- Fly from Wilmington International Airport (ILM) to Ft. Myers (RSW)plane ILM - RSW
7h 6m$221–847Fly Myrtle Beach to Fort Lauderdale–Hollywood International Airport, bus
- Fly from Myrtle Beach (MYR) to Fort Lauderdale–Hollywood International Airport (FLL)plane MYR - FLL
- Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus
5h 36m$154–833Bus, train
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
- Take the train from Charleston Amtrak Station to Winter Park Amtrak Stationtrain
- Take the bus from Orlando to Fort Myers Bus Stopbus
18h 37m$199–383Bus
- Take the bus from Myrtle Beach Bus Station to Camdenbus
- Take the bus from Camden to Jacksonvillebus
- Take the bus from Jacksonville to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus
20h 21m$151–266
Myrtle Beach (MYR) to Ft. Myers (RSW) flights
Questions & Answers
The cheapest way to get from Murrells Inlet to Fort Myers is to drive which costs $110 - $170 and takes 11h 23m.
The fastest way to get from Murrells Inlet to Fort Myers is to fly and bus which takes 5h 25m and costs $160 - $750.
The distance between Murrells Inlet and Fort Myers is 553 miles. The road distance is 613.2 miles.
The best way to get from Murrells Inlet to Fort Myers without a car is to bus and train via Jacksonville which takes 18h 13m and costs $230 - $400.
It takes approximately 7h 11m to get from Murrells Inlet to Fort Myers, including transfers.
The best way to get from Murrells Inlet to Fort Myers is to fly which takes 7h 11m and costs $380 - $650. Alternatively, you can bus, which costs $150 - $270 and takes 20h 21m.
Yes, the driving distance between Murrells Inlet to Fort Myers is 613 miles. It takes approximately 11h 23m to drive from Murrells Inlet to Fort Myers.
There are 2914+ hotels available in Fort Myers.
What companies run services between Murrells Inlet, SC, USA and Fort Myers, FL, USA?
American Airlines, Delta, and Southwest Airlines fly from Myrtle Beach (MYR) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a vehicle from Murrells Inlet to Fort Myers Bus Stop via Myrtle Beach Bus Station, Camden, Jacksonville, and Orlando Bus Station in around 20h 21m.
- Website
- delta.com
Flights from Myrtle Beach to Ft. Myers via Atlanta
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $70–370
Flights from Myrtle Beach to Tampa via Atlanta
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $65–350
Flights from Myrtle Beach to Orlando via Atlanta
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $60–330
Flights from Wilmington International Airport to Ft. Myers via Atlanta
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $80–400
- Website
- aa.com
Flights from Myrtle Beach to Ft. Myers via Charlotte
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $65–360
Flights from Myrtle Beach to Tampa via Charlotte
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $60–340
Flights from Myrtle Beach to Orlando via Charlotte
- Ave. Duration
- 3h 54m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $55–310
Flights from Wilmington International Airport to Ft. Myers via Charlotte
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $70–380
- Website
- flybreeze.com
Flights from Myrtle Beach to Tampa
- Ave. Duration
- 1h 37m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $75–600
Flights from Myrtle Beach to Orlando
- Ave. Duration
- 1h 40m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $75–370
Flights from Wilmington International Airport to Ft. Myers
- Ave. Duration
- 1h 59m
- When
- Monday and Friday
- Estimated price
- $150–750
Flights from Myrtle Beach to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 50m
- When
- Monday, Friday, Wednesday, and Saturday
- Estimated price
- $120–900
- Website
- southwest.com
Flights from Myrtle Beach to Ft. Myers via Nashville
- Ave. Duration
- 6h 40m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $95–440
Flights from Myrtle Beach to Ft. Myers via Columbus
- Ave. Duration
- 6h 15m
- When
- Saturday
- Estimated price
- $110–490
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Charleston Amtrak Station to Jacksonville
- Ave. Duration
- 4h 28m
- Frequency
- Once daily
- Estimated price
- $70–160
- Website
- https://www.amtrak.com/home.html
Train from Kingstree Station to Fort Lauderdale Amtrak Station
- Ave. Duration
- 14h 10m
- Frequency
- Once daily
- Estimated price
- $200–440
- Website
- https://www.amtrak.com/home.html
Train from Charleston Amtrak Station to Winter Park Amtrak Station
- Ave. Duration
- 7h 43m
- Frequency
- Once daily
- Estimated price
- $110–250
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Myrtle Beach Bus Station to Charleston Bus Station
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $15–30
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transit
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $11–23
- Website
- https://www.greyhound.com/
Bus from Myrtle Beach Bus Station to Camden
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- https://www.greyhound.com/
Bus from Camden to Jacksonville
- Ave. Duration
- 6h 35m
- Frequency
- Once daily
- Estimated price
- $45–95
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Jacksonville to Wildwood Amtrak Station
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Wildwood to Fort Myers
- Ave. Duration
- 4h 29m
- Frequency
- Once daily
- Estimated price
- $60–80
- Schedules at
- omnibusexpress.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Fort Lauderdale International Airport to Fort Myers Bus Stop
- Ave. Duration
- 2h 20m
- Frequency
- 3 times a day
- Estimated price
- $18–35
- Schedules at
- flixbus.com
Bus from Orlando to Fort Myers Bus Stop
- Ave. Duration
- 5h 5m
- Frequency
- 3 times a day
- Estimated price
- $29–50
- Schedules at
- flixbus.com
Bus from Jacksonville to Orlando Bus Station
- Ave. Duration
- 2h 35m
- Frequency
- Every 4 hours
- Estimated price
- $18–35
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 4h 35m
- Frequency
- 4 times a day
- Estimated price
- $28–50
- Schedules at
- flixbus.com
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Tampa International Airport to Fort Myers 7-11
- Ave. Duration
- 2h 10m
- Frequency
- 5 times a week
- Estimated price
- $30–60
- Website
- https://www.redcoachusa.com
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