There are 5 ways to get from Murrells Inlet to Durham by bus (Greyhound), car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus Greyhound US0645S
6h 45m$86–119Drive 190.6 mi
cheapest- Drive from Murrells Inlet to Durhamcar 190.6 mi
4h 23m$35–51Drive, train (Amtrak)
- Drive from Murrells Inlet to Kingstree Stationcar
- Take the train from Kingstree Station to Selma Stationtrain
- Take the train from Selma Station to Durham Amtrak Stationtrain
7h 1m$131–217Fly to Raleigh-Durham International Airport
- Fly from Myrtle Beach (MYR) to Raleigh-Durham International Airport (RDU)plane MYR - RDU
4h 55m$107–454Fly to Piedmont Triad International Airport, train
- Fly from Myrtle Beach (MYR) to Piedmont Triad International Airport (GSO)plane MYR - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
5h 37m$140–433
Myrtle Beach (MYR) to Raleigh-Durham International Airport (RDU) flights
Comparing Your Travel Options
The cheapest way to get from Murrells Inlet to Durham is to drive which costs $35 - $50 and takes 4h 23m.
The fastest way to get from Murrells Inlet to Durham is to drive which takes 4h 23m and costs $35 - $50.
No, there is no direct bus from Murrells Inlet station to Durham station. However, there are services departing from Myrtle Beach Bus Station and arriving at Durham Station via Capital Blvd at Crabtree Blvd, Blount St at GoRaleigh Station and Regional Transit Center. The journey, including transfers, takes approximately 6h 45m.
The distance between Murrells Inlet and Durham is 264 miles. The road distance is 191.7 miles.
The best way to get from Murrells Inlet to Durham without a car is to bus which takes 6h 45m and costs $85 - $120.
It takes approximately 6h 45m to get from Murrells Inlet to Durham, including transfers.
Murrells Inlet to Durham bus services, operated by Greyhound USA, depart from Myrtle Beach Bus Station.
The best way to get from Murrells Inlet to Durham is to bus which takes 6h 45m and costs $85 - $120. Alternatively, you can fly, which costs $100 - $460 and takes 4h 55m.
Murrells Inlet to Durham bus services, operated by Greyhound USA, arrive at Raleigh Bus Station.
Yes, the driving distance between Murrells Inlet to Durham is 192 miles. It takes approximately 4h 23m to drive from Murrells Inlet to Durham.
What companies run services between Murrells Inlet, SC, USA and Durham, NC, USA?
Greyhound USA operates a bus from Myrtle Beach Bus Station to Raleigh Bus Station once daily. Tickets cost $35–60 and the journey takes 4h 20m. Alternatively, American Airlines, Southwest Airlines, and three other airlines fly from Myrtle Beach (MYR) to Raleigh-Durham International Airport (RDU) hourly.
- Website
- aa.com
Flights from Myrtle Beach to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $60–400
Flights from Myrtle Beach to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 5h 26m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–480
Flights from Myrtle Beach to Piedmont Triad International Airport via Charlotte
- Ave. Duration
- 3h 39m
- When
- Every day
- Estimated price
- $40–300
Flights from Myrtle Beach to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 5h 46m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $75–400
- Website
- delta.com
Flights from Myrtle Beach to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $90–490
Flights from Myrtle Beach to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $65–370
Flights from Myrtle Beach to Piedmont Triad International Airport via Detroit
- Ave. Duration
- 6h 26m
- When
- Every day
- Estimated price
- $90–450
- Website
- southwest.com
Flights from Myrtle Beach to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $85–490
- Website
- united.com
Flights from Myrtle Beach to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 3h 42m
- When
- Saturday
- Estimated price
- $85–480
Flights from Myrtle Beach to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 3h 51m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $65–370
- Website
- flybreeze.com
Flights from Myrtle Beach to Raleigh-Durham International Airport via Pittsburgh
- Ave. Duration
- 4h 48m
- When
- Monday and Friday
- Estimated price
- $190–1,200
Flights from Myrtle Beach to Raleigh-Durham International Airport via Atlantic City
- Ave. Duration
- 5h 18m
- When
- Thursday and Sunday
- Estimated price
- $180–1,200
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Kingstree Station to Selma Station
- Ave. Duration
- 2h 59m
- Frequency
- Once daily
- Estimated price
- $90–150
- Website
- Amtrak
Train from Selma Station to Durham Amtrak Station
- Ave. Duration
- 1h 28m
- Frequency
- Once daily
- Estimated price
- $30–50
- Website
- Amtrak
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Raleigh Bus Station
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- $35–60
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 332+ hotels available in Durham.





