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How to get fromMurrells Inlet to Chicagoby plane, bus (Greyhound, Flixbus), car, train or bus

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There are 7 ways to get from Murrells Inlet to Chicago by plane, bus (Greyhound, Flixbus), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago O'Hare International Airport

    best
    1. Fly from Myrtle Beach (MYR) to Chicago O'Hare International Airport (ORD)planeMYR - ORD
    3h 34m
    $129–365

  2. Fly to Chicago Midway International Airport

    cheapest
    1. Fly from Myrtle Beach (MYR) to Chicago Midway International Airport (MDW)planeMYR - MDW
    3h 13m
    $119–465

  3. Bus

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus StationbusGreyhound US0641
    2. Take the bus from Atlanta Bus Station to Chicago Bus StationbusFlixBus 2512 / ...
    24h 41m
    $165–373

  4. Drive, train (Amtrak)

    1. Drive from Murrells Inlet to Kingstree Stationcar
    2. Take the train from Kingstree Station to Petersburg Amtrak Stationtrain
    3. Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain
    29h 54m
    $216–637

  5. Drive 903.3 mi

    1. Drive from Murrells Inlet to Chicagocar903.3 mi
    16h 35m
    $165–239

  6. Bus via Hurricane

    1. Take the bus from Myrtle Beach, SC to Charlotte Bus Stationbus
    2. Take the bus from Charlotte Bus Station to Hurricanebus
    3. Take the bus from Hurricane to Columbus - Mound Stbus
    4. Take the bus from Columbus - Mound St to Chicagobus
    27h 46m
    $180–373

  7. Bus, train

    1. Take the bus from Myrtle Beach, SC to Florencebus
    2. Take the bus from Florence Bus Station to Fayetteville Bus Stationbus
    3. Take the train from Fayetteville Amtrak Station to Petersburg Amtrak Stationtrain
    4. Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain
    31h 4m
    $292–833

Myrtle Beach (MYR) to Chicago O'Hare International Airport (ORD) flights

Calendar14Weekly Planes
Duration2h 31mAverage Duration
Ticket$58Cheapest Price
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Questions & Answers

What companies run services between Murrells Inlet, SC, USA and Chicago, IL, USA?

American Airlines, United Airlines, and Southwest Airlines fly from Myrtle Beach (MYR) to Chicago O'Hare International Airport (ORD) twice daily. Alternatively, you can take a vehicle from Murrells Inlet to Chicago Bus Station via Myrtle Beach Bus Station and Atlanta Bus Station in around 24h 41m.

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