Rome2Rio

How to get fromMurrells Inlet to Chicagoby plane, bus (Greyhound), car, train, or bus

Find Transport to Chicago

See all options

There are 6 ways to get from Murrells Inlet to Chicago by plane, bus (Greyhound), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago Midway International Airport

    best
    1. Fly from Myrtle Beach (MYR) to Chicago Midway International Airport (MDW)plane plane MYR - MDW
    3h 8m
    $108–393

  2. Bus (Greyhound)

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S
    2. Take the bus from Atlanta Bus Station to Chicago Train Stationbus bus Greyhound US0100
    26h 11m
    $208–371

  3. Drive, train (Amtrak)

    1. Drive from Murrells Inlet to Kingstree Stationcar car
    2. Take the train from Kingstree Station to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain train
    29h 46m
    $401–827

  4. Drive 903.9 mi

    1. Drive from Murrells Inlet to Chicagocar car 903.9 mi
    16h 45m
    $165–239

  5. Fly to Chicago O'Hare International Airport

    1. Fly from Myrtle Beach (MYR) to Chicago O'Hare International Airport (ORD)plane plane MYR - ORD
    3h 38m
    $333–853

  6. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus bus Greyhound US0645S
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train Floridian
    36h 37m
    $465–883

Myrtle Beach (MYR) to Chicago Midway International Airport (MDW) flights

Calendar14Weekly Planes
Duration3h 46mAverage Duration
Ticket$67Cheapest Price
See schedules

Questions & Answers

Map of how to get from Murrells Inlet to Chicago.ExpandLaunch map view
  • Distance: 762.1 mi
  • Duration: 3h 8m

What companies run services between Murrells Inlet, SC, USA and Chicago, IL, USA?

Southwest Airlines flies from Myrtle Beach (MYR) to Chicago Midway International Airport (MDW) twice daily. Alternatively, you can take a vehicle from Murrells Inlet to Chicago Train Station via Myrtle Beach Bus Station and Atlanta Bus Station in around 26h 11m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers