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How to get fromMurrells Inlet to Chicagoby plane, bus (Greyhound, Flixbus), car, train or bus

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There are 6 ways to get from Murrells Inlet to Chicago by plane, bus (Greyhound, Flixbus), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago Midway International Airport

    best
    1. Fly from Myrtle Beach (MYR) to Chicago Midway International Airport (MDW)plane plane MYR - MDW
    3h 18m
    $128–513

  2. Bus

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus Greyhound US0641
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus Greyhound US0100
    26h 16m
    $198–411

  3. Drive, train (Amtrak)

    1. Drive from Murrells Inlet to Kingstree Stationcar car
    2. Take the train from Kingstree Station to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain train
    29h 55m
    $346–807

  4. Drive 903.3 mi

    1. Drive from Murrells Inlet to Chicagocar car 903.3 mi
    16h 46m
    $165–239

  5. Fly to Chicago O'Hare International Airport

    1. Fly from Myrtle Beach (MYR) to Chicago O'Hare International Airport (ORD)plane plane MYR - ORD
    3h 41m
    $133–333

  6. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    2. Take the bus from Wilmington Amtrak Station to Wilsonbus bus
    3. Take the train from Wilson to Raleigh Union Stationtrain train
    4. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    34h 56m
    $411–881

Myrtle Beach (MYR) to Chicago Midway International Airport (MDW) flights

Calendar16Weekly Planes
Duration4h 29mAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

What companies run services between Murrells Inlet, SC, USA and Chicago, IL, USA?

Southwest Airlines flies from Myrtle Beach (MYR) to Chicago Midway International Airport (MDW) twice daily. Alternatively, you can take a vehicle from Murrells Inlet to Chicago Bus Station via Myrtle Beach Bus Station and Atlanta Bus Station in around 26h 16m.

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