Rome2Rio

How to get fromMurphysboro to Detroitby bus, plane, train (Amtrak), bus (Amtrak, Flixbus, Greyhound), car or bus (Flixbus)

Find Transport to Detroit

See all options

There are 7 ways to get from Murphysboro to Detroit by bus, plane, train (Amtrak), bus (Amtrak, Flixbus, Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Lambert–St. Louis International Airport, fly

    best
    1. Take the bus from Carbondale to St. Louisbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Detroit (DTW)plane plane STL - DTW
    6h 44m
    $245–493

  2. Bus

    cheapest
    1. Take the bus from Carbondale to St. Louisbus bus
    2. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis, IN to Detroit, MIbus bus
    13h 41m
    $97–228

  3. Train (Amtrak)

    1. Take the train from Carbondale to Chicago Union Stationtrain train Saluki / ...
    2. Take the train from Chicago Union Station to Detroittrain train Wolverine
    12h 1m
    $174–383

  4. Drive 540 mi

    1. Drive from Murphysboro to Detroitcar car 540 mi
    9h 28m
    $99–143

  5. Bus to Nashville, fly

    1. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    2. Fly from Nashville (BNA) to Detroit (DTW)plane plane BNA - DTW
    8h 40m
    $138–352

  6. Fly from Williamson County Regional Airport

    1. Fly from Williamson County Regional Airport (MWA) to Detroit (DTW)plane plane MWA - DTW
    6h 31m
    $161–490

  7. Bus via Auburn Gresham (Flixbus)

    1. Take the bus from Carbondale Intermodal Station to Chicagobus bus FlixBus N2521
    2. Take the bus from Chicago to Detroit Bus Stationbus bus FlixBus 2552
    17h 36m
    $109–188

Lambert–St. Louis International Airport (STL) to Detroit (DTW) flights

Calendar57Weekly Planes
Duration2h 14mAverage Duration
Ticket$75Cheapest Price
See schedules

Questions & Answers

What companies run services between Murphysboro, IL, USA and Detroit, MI, USA?

You can take a vehicle from Murphysboro to Detroit via Carbondale and Chicago Union Station in around 12h 1m. Alternatively, you can take a vehicle from Murphysboro to Detroit, MI via Carbondale, St. Louis, St Louis Bus Station, and Indianapolis, IN in around 13h 41m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Where to next?

Trips from Murphysboro

Trips to Detroit

Popular routes