There are 8 ways to get from Mobile to Sikeston by bus, plane, taxi, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Pensacola International Airport, fly to Cape Girardeau Municipal Airport, taxi
best- Take the bus from Mobile Bus Station to Pensacola Airportbus
- Fly from Pensacola International Airport (PNS) to Cape Girardeau Municipal Airport (CGI)plane PNS - CGI
- Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi
5h 59m$280–529Drive 503 mi
cheapest- Drive from Mobile to Sikestoncar 503 mi
9h 36m$92–133Bus, train, drive
- Take the bus from Mobile Bus Station to New Orleans Bus Stationbus
- Take the train from New Orleans Union Passenger Terminal to Fulton Amtrak Stationtrain
- Drive from Fulton Amtrak Station to Sikestoncar
18h 4m$159–362Bus, taxi
- Take the bus from Mobile Bus Station to New Orleans Bus Stationbus
- Take the bus from New Orleans Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Sikestontaxi
18h 32m$207–353Bus to Pensacola International Airport, fly to Lambert–St. Louis International Airport, bus, taxi
- Take the bus from Mobile Bus Station to Pensacola Airportbus
- Fly from Pensacola International Airport (PNS) to Lambert–St. Louis International Airport (STL)plane PNS - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Sikestontaxi
9h 55m$262–1,027Bus to Destin–Fort Walton Beach Airport, fly to Midamerica St. Louis Airport, bus, taxi
- Take the bus from Mobile to Crestviewbus
- Fly from Destin–Fort Walton Beach Airport (VPS) to Midamerica St. Louis Airport (BLV)plane VPS - BLV
- Take the bus from St Louis Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Sikestontaxi
9h 45m$294–663Bus to Pensacola International Airport, fly to Nashville, bus, drive
- Take the bus from Mobile Bus Station to Pensacola Airportbus
- Fly from Pensacola International Airport (PNS) to Nashville (BNA)plane PNS - BNA
- Take the bus from Nashville Bus Station to Paducah Bus Stationbus
- Drive from Paducah Bus Station to Sikestoncar
10h 38m$149–486Fly Mobile Regional Airport to Cape Girardeau Municipal Airport, taxi
- Fly from Mobile Regional Airport (MOB) to Cape Girardeau Municipal Airport (CGI)plane MOB - CGI
- Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi
10h 52m$178–596
Pensacola International Airport (PNS) to Cape Girardeau Municipal Airport (CGI) flights
Questions & Answers
The cheapest way to get from Mobile to Sikeston is to drive which costs $90 - $140 and takes 9h 36m.
The fastest way to get from Mobile to Sikeston is to bus and fly and taxi which takes 5h 59m and costs $280 - $550.
The distance between Mobile and Sikeston is 589 miles. The road distance is 505.9 miles.
The best way to get from Mobile to Sikeston without a car is to bus and taxi which takes 18h 32m and costs $200 - $360.
It takes approximately 5h 59m to get from Mobile to Sikeston, including transfers.
Yes, the driving distance between Mobile to Sikeston is 506 miles. It takes approximately 9h 36m to drive from Mobile to Sikeston.
There are 13+ hotels available in Sikeston.
What companies run services between Mobile, AL, USA and Sikeston, MO, USA?
There is no direct connection from Mobile to Sikeston. However, you can take the line 9 bus to Govt WB Across from Greyhound, walk to Mobile Bus Station, take the bus to Pensacola Airport, walk to Pensacola International Airport (PNS) airport, fly to Cape Girardeau Municipal Airport (CGI), then take the taxi to Sikeston. Alternatively, you can take a bus from St Francis WB at Joachim to Sikeston via Govt WB Across from Greyhound, Mobile Bus Station, New Orleans Bus Station, New Orleans Union Passenger Terminal, and Fulton Amtrak Station in around 18h 4m.
- Website
- southwest.com
Flights from Pensacola International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $140–850
Flights from Pensacola International Airport to Nashville
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $60–390
- Website
- contouraviation.com
Flights from Pensacola International Airport to Cape Girardeau Municipal Airport
- Ave. Duration
- 1h 45m
- When
- Wednesday and Saturday
- Estimated price
- $190–410
Flights from Mobile Regional Airport to Cape Girardeau Municipal Airport via Dallas/Ft.Worth
- Ave. Duration
- 9h 47m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–500
Flights from Mobile Regional Airport to Cape Girardeau Municipal Airport via Atlanta, Pensacola International Airport
- Ave. Duration
- 6h 40m
- When
- Wednesday and Saturday
- Estimated price
- $170–800
Flights from Mobile Regional Airport to Cape Girardeau Municipal Airport via Charlotte, Chicago O'Hare
- Ave. Duration
- 8h 15m
- When
- Wednesday
- Estimated price
- $120–600
Flights from Mobile Regional Airport to Cape Girardeau Municipal Airport via Charlotte, Dallas/Ft.Worth
- Ave. Duration
- 9h 54m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–700
Flights from Mobile Regional Airport to Cape Girardeau Municipal Airport via Houston, Dallas/Ft.Worth
- Ave. Duration
- 11h 13m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–900
- Website
- delta.com
Flights from Pensacola International Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $160–900
Flights from Pensacola International Airport to Nashville via Atlanta
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- $65–410
- Website
- allegiantair.com
Flights from Destin–Fort Walton Beach Airport to Midamerica St. Louis Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $60–350
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from New Orleans Union Passenger Terminal to Fulton Amtrak Station
- Ave. Duration
- 11h 17m
- Frequency
- Once daily
- Estimated price
- $130–300
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Mobile Bus Station to Pensacola Airport
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $10–19
- Website
- https://www.greyhound.com/
Bus from Mobile Bus Station to New Orleans Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- 3 times a day
- Estimated price
- $23–45
- Website
- https://www.greyhound.com/
Bus from New Orleans Bus Station to Cape Girardeau
- Ave. Duration
- 12h 40m
- Frequency
- Once daily
- Estimated price
- $100–190
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $19–35
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Mobile Bus Station to New Orleans Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- 6 times a week
- Estimated price
- $16–29
- Schedules at
- flixbus.com
Bus from Nashville Bus Station to Paducah Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $16–28
- Schedules at
- flixbus.com
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Mobile to Crestview
- Ave. Duration
- 1h 43m
- Frequency
- Once daily
- Estimated price
- $45–65
- Schedules at
- omnibusexpress.com
- Ave. Duration
- 33 min
- Estimated price
- $80–120
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
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