There are 7 ways to get from Mobile to Sikeston by bus, train, taxi, car, plane, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train, taxi
best- Take the bus from Mobile Bus Station to New Orleans Bus Stationbus
- Take the train from New Orleans Union Passenger Terminal to Fulton Amtrak Stationtrain
- Take the taxi from Fulton Amtrak Station to Sikestontaxi
18h 4m$213–383Drive 499.7 mi
cheapest- Drive from Mobile to Sikestoncar 499.7 mi
9h 44m$92–132Bus, taxi
- Take the bus from Mobile Bus Station to New Orleans Bus Stationbus
- Take the bus from New Orleans Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Sikestontaxi
18h 32m$153–263Fly Mobile Regional Airport to Barkley Regional Airport, taxi
- Fly from Mobile Regional Airport (MOB) to Barkley Regional Airport (PAH)plane MOB - PAH
- Take the taxi from Barkley Regional Airport (PAH) to Sikestontaxi
11h 3m$258–824Bus
- Take the bus from Mobile Bus Station to Lafayettebus
- Take the bus from Lafayette to Memphis Bus Stationbus
- Take the bus from Tornado Bus Co - West Memphis to Flying J - Matthewsbus
22h 35m$180–391Bus to Pensacola International Airport, fly to Lambert–St. Louis International Airport, bus, taxi
- Take the bus from Mobile Bus Station to Pensacola Airportbus
- Fly from Pensacola International Airport (PNS) to Lambert–St. Louis International Airport (STL)plane PNS - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Sikestontaxi
9h 55m$230–823Fly Mobile Regional Airport to Cape Girardeau Municipal Airport, taxi
- Fly from Mobile Regional Airport (MOB) to Cape Girardeau Municipal Airport (CGI)plane MOB - CGI
- Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi
9h 27m$181–619
Mobile Regional Airport (MOB) to Barkley Regional Airport (PAH) flights
Questions & Answers
The cheapest way to get from Mobile to Sikeston is to drive which costs $90 - $140 and takes 9h 44m.
The fastest way to get from Mobile to Sikeston is to fly and taxi which takes 9h 27m and costs $180 - $650.
The distance between Mobile and Sikeston is 750 miles. The road distance is 502.6 miles.
The best way to get from Mobile to Sikeston without a car is to bus and train and taxi which takes 18h 4m and costs $210 - $390.
It takes approximately 18h 4m to get from Mobile to Sikeston, including transfers.
Yes, the driving distance between Mobile to Sikeston is 503 miles. It takes approximately 9h 44m to drive from Mobile to Sikeston.
There are 13+ hotels available in Sikeston.
What companies run services between Mobile, AL, USA and Sikeston, MO, USA?
You can take a bus from St Joseph SB Near St Louis St to Sikeston via Govt WB Across from Greyhound, Mobile Bus Station, Lafayette, Airways Transit Center, William Hudson Transit Center, Tornado Bus Co - West Memphis, and Flying J - Matthews in around 22h 35m.
- Website
- contouraviation.com
Flights from Mobile Regional Airport to Barkley Regional Airport via Charlotte
- Ave. Duration
- 7h 6m
- When
- Every day
- Estimated price
- $130–700
Flights from Mobile Regional Airport to Cape Girardeau Municipal Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 15m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–550
Flights from Mobile Regional Airport to Cape Girardeau Municipal Airport via Atlanta, Dallas/Ft.Worth
- Ave. Duration
- 8h 1m
- When
- Wednesday and Saturday
- Estimated price
- $140–650
Flights from Mobile Regional Airport to Cape Girardeau Municipal Airport via Charlotte, Dallas/Ft.Worth
- Ave. Duration
- 9h 21m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $170–750
Flights from Mobile Regional Airport to Cape Girardeau Municipal Airport via Houston, Dallas/Ft.Worth
- Ave. Duration
- 9h 51m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $230–1,100
- Website
- southwest.com
Flights from Pensacola International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 50m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–650
Flights from Pensacola International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 10m
- When
- Monday to Friday
- Estimated price
- $120–700
Flights from Pensacola International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 4h 20m
- When
- Thursday and Friday
- Estimated price
- $160–800
- Website
- united.com
Flights from Mobile Regional Airport to Barkley Regional Airport via Houston
- Ave. Duration
- 9h 43m
- When
- Tuesday to Saturday
- Estimated price
- $140–700
- Website
- delta.com
Flights from Pensacola International Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $130–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from New Orleans Union Passenger Terminal to Fulton Amtrak Station
- Ave. Duration
- 11h 17m
- Frequency
- Once daily
- Estimated price
- $50–180
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $50–130
- Coach Seat short notice purchase
- $65–180
- Business - advance purchase
- $90–390
- Business Class
- $150–410
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Mobile Bus Station to New Orleans Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- 3 times a day
- Estimated price
- $23–35
- Website
- https://www.greyhound.com/
Bus from New Orleans Bus Station to Cape Girardeau
- Ave. Duration
- 12h 40m
- Frequency
- Once daily
- Estimated price
- $60–140
- Website
- https://www.greyhound.com/
Bus from Mobile Bus Station to Pensacola Airport
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $25–55
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $21–27
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Mobile Bus Station to New Orleans Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- 6 times a week
- Estimated price
- $24–35
- Schedules at
- flixbus.com
Bus from Mobile Bus Station to Lafayette
- Ave. Duration
- 5h 10m
- Frequency
- 6 times a week
- Estimated price
- $30–90
- Schedules at
- flixbus.com
- Adult
- $30–90
Bus from Lafayette to Memphis Bus Station
- Ave. Duration
- 9h 45m
- Frequency
- 5 times a week
- Estimated price
- $60–110
- Schedules at
- flixbus.com
- Adult
- $60–110
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Tornado Bus Co - West Memphis to Flying J - Matthews
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $45–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–140
- Ave. Duration
- 53 min
- Estimated price
- $70–170
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
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