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How to get fromMobile to Roanokeby plane, bus (Greyhound), train (Amtrak), car, train, or bus

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There are 7 ways to get from Mobile to Roanoke by plane, bus (Greyhound), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mobile Regional Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane MOB - ROA
    8h 30m
    $76–374

  2. Bus to Pensacola International Airport, fly

    cheapest
    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane PNS - ROA
    8h 57m
    $73–362

  3. Bus (Greyhound)

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Roanoke Bus Stopbus bus
    20h 12m
    $131–258

  4. Train (Amtrak)

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Lynchburgtrain train
    3. Take the train from Lynchburg to Roanoketrain train
    30h 26m
    $367–773

  5. Drive 730.7 mi

    1. Drive from Mobile to Roanokecar car 730.7 mi
    13h 6m
    $134–193

  6. Train to Gulfport-Biloxi Regional Airport, fly

    1. Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane GPT - ROA
    7h 35m
    $132–549

  7. Bus, train

    1. Take the bus from Mobile to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Lynchburg Transit Centerbus bus
    4. Take the train from Lynchburg to Roanoketrain train
    20h 39m
    $193–302

Mobile to Roanoke by bus (Greyhound)

Calendar7Weekly Buses
Duration20h 12mAverage Duration
Ticket$131Cheapest Price
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Questions & Answers

Map of how to get from Mobile to Roanoke.ExpandLaunch map view
  • Distance: 688.8 mi
  • Duration: 8h 30m

What companies run services between Mobile, AL, USA and Roanoke, VA, USA?

Delta and American Airlines fly from Mobile Regional Airport (MOB) to Roanoke Regional Airport-Woodrum Field (ROA) 5 times a day. Alternatively, you can take a bus from St Joseph SB Near St Louis St to Roanoke Bus Stop via Govt WB Across from Greyhound, Mobile Bus Station, Montgomery Intermodal Center, and Nashville Bus Station in around 20h 12m.

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