There are 8 ways to get from Mobile to Poplar Bluff by plane, car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Mobile Regional Airport to Cape Girardeau Municipal Airport, drive
best- Fly from Mobile Regional Airport (MOB) to Cape Girardeau Municipal Airport (CGI)plane MOB - CGI
- Drive from Cape Girardeau Municipal Airport (CGI) to Poplar Bluffcar
10h 24m$139–516Drive 504.3 mi
cheapest- Drive from Mobile to Poplar Bluffcar 504.3 mi
10h 2m$92–133Bus, drive
- Take the bus from Mobile Bus Station to New Orleans Bus Stationbus
- Take the bus from New Orleans Bus Station to Cape Girardeaubus
- Drive from Cape Girardeau to Poplar Bluffcar
19h 8m$135–216Train, bus via Carbondale
- Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Carbondaletrain
- Take the bus from Carbondale to St. Louisbus
- Take the train from St. Louis to Poplar Bluff Stationtrain
25h 58m$474–828Bus to Pensacola International Airport, fly to Lambert–St. Louis International Airport, train
- Take the bus from Mobile Bus Station to Pensacola Airportbus
- Fly from Pensacola International Airport (PNS) to Lambert–St. Louis International Airport (STL)plane PNS - STL
- Take the train from St. Louis to Poplar Bluff Stationtrain
10h 40m$184–619Fly Mobile Regional Airport to Mc Kellar-Sipes Regional Airport, drive
- Fly from Mobile Regional Airport (MOB) to Mc Kellar-Sipes Regional Airport (MKL)plane MOB - MKL
- Drive from Mc Kellar-Sipes Regional Airport (MKL) to Poplar Bluffcar
8h 4m$121–457Bus to Destin–Fort Walton Beach Airport, fly to Midamerica St. Louis Airport, train
- Take the bus from Mobile to Crestviewbus
- Fly from Destin–Fort Walton Beach Airport (VPS) to Midamerica St. Louis Airport (BLV)plane VPS - BLV
- Take the train from St. Louis to Poplar Bluff Stationtrain
10h 50m$280–678Train, bus
- Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain
- Take the bus from New Orleans Bus Station to St Louis Bus Stationbus
- Take the train from St. Louis to Poplar Bluff Stationtrain
24h 10m$240–446
Mobile Regional Airport (MOB) to Cape Girardeau Municipal Airport (CGI) flights
Comparing Your Travel Options
The cheapest way to get from Mobile to Poplar Bluff is to drive which costs $90 - $140 and takes 10h 2m.
The fastest way to get from Mobile to Poplar Bluff is to fly and drive which takes 8h 4m and costs $120 - $460.
The distance between Mobile and Poplar Bluff is 544 miles. The road distance is 507.2 miles.
The best way to get from Mobile to Poplar Bluff without a car is to train and bus via Carbondale which takes 25h 58m and costs $470 - $850.
It takes approximately 10h 24m to get from Mobile to Poplar Bluff, including transfers.
Yes, the driving distance between Mobile to Poplar Bluff is 507 miles. It takes approximately 10h 2m to drive from Mobile to Poplar Bluff.
There are 10+ hotels available in Poplar Bluff.
What companies run services between Mobile, AL, USA and Poplar Bluff, MO, USA?
There is no direct connection from Mobile to Poplar Bluff. However, you can take the taxi to Mobile Regional Airport (MOB) airport, fly to Cape Girardeau Municipal Airport (CGI), then drive to Poplar Bluff. Alternatively, you can take a bus from Govt WB and Joachim St to Poplar Bluff via Govt WB Across from Greyhound, Mobile Bus Station, New Orleans Bus Station, and Cape Girardeau in around 19h 8m.
- Website
- allegiantair.com
Flights from Destin–Fort Walton Beach Airport to Midamerica St. Louis Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $65–380
- Website
- southwest.com
Flights from Pensacola International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $80–460
Flights from Pensacola International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 20m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $85–470
- Website
- contouraviation.com
Flights from Mobile Regional Airport to Cape Girardeau Municipal Airport via Dallas/Ft.Worth
- Ave. Duration
- 9h 12m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–460
Flights from Mobile Regional Airport to Cape Girardeau Municipal Airport via Atlanta, Dallas/Ft.Worth
- Ave. Duration
- 8h 29m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–550
Flights from Mobile Regional Airport to Cape Girardeau Municipal Airport via Houston, Dallas/Ft.Worth
- Ave. Duration
- 10h 6m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $260–1,200
Flights from Mobile Regional Airport to Cape Girardeau Municipal Airport via Charlotte, Dallas/Ft.Worth
- Ave. Duration
- 13h 20m
- When
- Sunday
- Estimated price
- $150–650
- Website
- delta.com
Flights from Pensacola International Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $90–490
- Website
- keylimeair.com
Flights from Mobile Regional Airport to Mc Kellar-Sipes Regional Airport via Atlanta
- Ave. Duration
- 5h
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $65–380
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Mobile, AL to New Orleans, LA - Union Passenger Terminal
- Ave. Duration
- 3h 43m
- Frequency
- Twice daily
- Estimated price
- $30–120
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Carbondale
- Ave. Duration
- 13h 28m
- Frequency
- Once daily
- Estimated price
- $340–550
- Website
- Amtrak
Train from St. Louis to Poplar Bluff Station
- Ave. Duration
- 3h 47m
- Frequency
- Once daily
- Estimated price
- $90–140
- Website
- Amtrak
Train from St. Louis to Poplar Bluff Station
- Ave. Duration
- 3h 47m
- Frequency
- Once daily
- Estimated price
- $90–140
- Website
- Amtrak
Train from St. Louis to Poplar Bluff Station
- Ave. Duration
- 3h 47m
- Frequency
- Once daily
- Estimated price
- $90–140
- Website
- Amtrak
Train from Mobile, AL to New Orleans, LA - Union Passenger Terminal
- Ave. Duration
- 3h 43m
- Frequency
- Twice daily
- Estimated price
- $30–120
- Website
- Amtrak
Train from St. Louis to Poplar Bluff Station
- Ave. Duration
- 3h 47m
- Frequency
- Once daily
- Estimated price
- $90–140
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Mobile Bus Station to New Orleans Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- 3 times a day
- Estimated price
- $24–40
- Website
- Greyhound
Bus from New Orleans Bus Station to Cape Girardeau
- Ave. Duration
- 12h 40m
- Frequency
- Once daily
- Estimated price
- $100–160
- Website
- Greyhound
Bus from Mobile Bus Station to Pensacola Airport
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $10–16
- Website
- Greyhound
Bus from New Orleans Bus Station to St Louis Bus Station
- Ave. Duration
- 14h 40m
- Frequency
- Once daily
- Estimated price
- $120–190
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Mobile Bus Station to New Orleans Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- 6 times a week
- Estimated price
- $21–35
- Schedules at
- Flixbus USA
Bus from Carbondale to St. Louis
- Ave. Duration
- 1h 55m
- Frequency
- 5 times a week
- Estimated price
- $14–22
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Carbondale to St. Louis
- Ave. Duration
- 2h
- Frequency
- Once daily
- Website
- Amtrak
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- Omnibus Express
Bus from Mobile to Crestview
- Ave. Duration
- 1h 43m
- Frequency
- Once daily
- Estimated price
- $45–65
- Schedules at
- Omnibus Express
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