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How to get fromMobile to Louisvilleby bus, plane, bus (Greyhound, Amtrak), car or bus (Greyhound)

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There are 8 ways to get from Mobile to Louisville by bus, plane, bus (Greyhound, Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Destin–Fort Walton Beach Airport, fly to Louisville International Airport

    best
    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Louisville International Airport (SDF)plane plane VPS - SDF
    6h 8m
    $180–629

  2. Fly Mobile Regional Airport to Blue Grass Airport, drive

    cheapest
    1. Fly from Mobile Regional Airport (MOB) to Blue Grass Airport (LEX)plane plane MOB - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    8h 32m
    $76–379

  3. Bus

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    15h 37m
    $112–210

  4. Drive 598 mi

    1. Drive from Mobile to Louisvillecar car 598 mi
    11h
    $110–158

  5. Fly Mobile Regional Airport to Louisville International Airport

    1. Fly from Mobile Regional Airport (MOB) to Louisville International Airport (SDF)plane plane MOB - SDF
    8h 17m
    $93–522

  6. Bus to Pensacola International Airport, fly to Louisville International Airport

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Louisville International Airport (SDF)plane plane PNS - SDF
    8h 29m
    $122–656

  7. Bus to Gulfport-Biloxi Regional Airport, fly to Louisville International Airport

    1. Take the bus from Mobile to Gulfportbus bus
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Louisville International Airport (SDF)plane plane GPT - SDF
    9h 23m
    $200–731

  8. Bus via Preston @ Vim

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Nashville Bus Stationbus bus
    3. Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus bus
    16h 30m
    $135–315

Mobile to Louisville by bus

Calendar7Weekly Buses
Duration15h 37mAverage Duration
Ticket$112Cheapest Price
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Questions & Answers

What companies run services between Mobile, AL, USA and Louisville, KY, USA?

You can take a bus from St Joseph SB Near St Louis St to Louisville, KY via Govt WB Across from Greyhound, Mobile Bus Station, Montgomery Intermodal Center, and Nashville in around 15h 37m. Alternatively, Delta, United Airlines, and American Airlines fly from Mobile Regional Airport (MOB) to Louisville International Airport (SDF) every 3 hours.

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