There are 5 ways to get from Mobile to Key West (Island) by plane, bus, ferry, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Mobile Regional Airport
best- Fly from Mobile Regional Airport (MOB) to Key West International Airport (EYW)plane MOB - EYW
4h 32m$107–417Bus to Pensacola International Airport, fly
cheapest- Take the bus from Mobile Bus Station to Pensacola Airportbus
- Fly from Pensacola International Airport (PNS) to Key West International Airport (EYW)plane PNS - EYW
6h 53m$66–326Bus, ferry
- Take the bus from Mobile to Fort Myersbus Houston
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry Fort Myers Beach
17h 30m$287–330Drive 858.7 mi
- Drive from Mobile to Key Westcar 858.7 mi
15h 29m$157–227Train to Gulfport-Biloxi Regional Airport, fly
- Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain
- Fly from Gulfport-Biloxi Regional Airport (GPT) to Key West International Airport (EYW)plane GPT - EYW
8h 2m$129–469
Mobile Regional Airport (MOB) to Key West International Airport (EYW) flights
Comparing Your Travel Options
The cheapest way to get from Mobile to Key West (Island) is to bus and fly which costs $65 - $330 and takes 6h 53m.
The fastest way to get from Mobile to Key West (Island) is to fly which takes 4h 32m and costs $100 - $420.
The distance between Mobile and Key West (Island) is 597 miles. The road distance is 863.7 miles.
The best way to get from Mobile to Key West (Island) without a car is to bus and ferry which takes 17h 30m and costs $280 - $330.
It takes approximately 4h 32m to get from Mobile to Key West (Island), including transfers.
Key West (Island) is 1h ahead of Mobile. It is currently 2:41 PM in Mobile and 3:41 PM in Key West (Island).
Yes, the driving distance between Mobile to Key West (Island) is 864 miles. It takes approximately 15h 29m to drive from Mobile to Key West (Island).
There are 920+ hotels available in Key West (Island).
What companies run services between Mobile, AL, USA and Key West (Island), FL, USA?
Delta and American Airlines fly from Mobile Regional Airport (MOB) to Key West International Airport (EYW) 3 times a day.
- Website
- delta.com
Flights from Mobile Regional Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $75–380
Flights from Gulfport-Biloxi Regional Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $75–390
Flights from Pensacola International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $70–350
- Website
- aa.com
Flights from Mobile Regional Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 57m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $90–430
Flights from Gulfport-Biloxi Regional Airport to Key West International Airport via Charlotte
- Ave. Duration
- 7h 25m
- When
- Tuesday
- Estimated price
- $95–440
Flights from Gulfport-Biloxi Regional Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 10h 54m
- When
- Every day
- Estimated price
- $110–480
Flights from Pensacola International Airport to Key West International Airport via Miami
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $55–310
Flights from Pensacola International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $85–400
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Mobile Amtrak Sta to Gulfport Amtrak Sta
- Ave. Duration
- 1h 39m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Amtrak
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- Omnibus Express
Bus from Mobile to Fort Myers
- Ave. Duration
- 12h 4m
- Frequency
- Once daily
- Estimated price
- $110–140
- Schedules at
- Omnibus Express
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Mobile Bus Station to Pensacola Airport
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $10–16
- Website
- Greyhound
- Phone
- +1 239-463-5733
- Website
- Key West Express
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- Key West Express
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide











