There are 7 ways to get from Mobile to Key West (Island) by plane, bus, ferry, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Mobile Regional Airport
best- Fly from Mobile Regional Airport (MOB) to Key West International Airport (EYW)plane MOB - EYW
9h 9m$100–600Bus, ferry
- Take the bus from Mobile to Fort Myersbus Houston
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry Fort Myers Beach
17h 30m$270–313Drive 858.7 mi
- Drive from Mobile to Key Westcar 858.7 mi
15h 28m$157–227Bus to Destin–Fort Walton Beach Airport, fly
- Take the bus from Mobile to Crestviewbus
- Fly from Destin–Fort Walton Beach Airport (VPS) to Key West International Airport (EYW)plane VPS - EYW
7h 7m$179–606Bus to Pensacola International Airport, fly
- Take the bus from Mobile Bus Station to Pensacola Airportbus
- Fly from Pensacola International Airport (PNS) to Key West International Airport (EYW)plane PNS - EYW
7h 33m$196–653Bus to Gulfport-Biloxi Regional Airport, fly
- Take the bus from Mobile to Gulfportbus
- Fly from Gulfport-Biloxi Regional Airport (GPT) to Key West International Airport (EYW)plane GPT - EYW
9h 30m$209–728Bus, taxi to Northwest Florida Beaches International Airport, fly
- Take the bus from Love's Travel Stop - Loxley to Whataburger - Defuniak Springsbus
- Take the taxi from Whataburger - Defuniak Springs to Northwest Florida Beaches International Airport (ECP)taxi
- Fly from Northwest Florida Beaches International Airport (ECP) to Key West International Airport (EYW)plane ECP - EYW
8h 50m$296–890
Mobile Regional Airport (MOB) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Mobile to Key West (Island) is to drive which costs $150 - $230 and takes 15h 28m.
The fastest way to get from Mobile to Key West (Island) is to bus and fly which takes 7h 7m and costs $170 - $650.
The distance between Mobile and Key West (Island) is 614 miles. The road distance is 863.7 miles.
The best way to get from Mobile to Key West (Island) without a car is to bus and ferry which takes 17h 30m and costs $270 - $320.
It takes approximately 9h 9m to get from Mobile to Key West (Island), including transfers.
Key West (Island) is 1h ahead of Mobile. It is currently 2:00 PM in Mobile and 3:00 PM in Key West (Island).
Yes, the driving distance between Mobile to Key West (Island) is 864 miles. It takes approximately 15h 28m to drive from Mobile to Key West (Island).
There are 831+ hotels available in Key West (Island).
What companies run services between Mobile, AL, USA and Key West (Island), FL, USA?
American Airlines, United Airlines, and Delta fly from Mobile Regional Airport (MOB) to Key West International Airport (EYW) every 4 hours.
- Website
- aa.com
Flights from Mobile Regional Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $130–650
Flights from Mobile Regional Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 38m
- When
- Every day
- Estimated price
- $150–750
Flights from Destin–Fort Walton Beach Airport to Key West International Airport via Miami
- Ave. Duration
- 3h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–480
Flights from Destin–Fort Walton Beach Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $120–650
Flights from Pensacola International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $95–600
Flights from Pensacola International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $140–750
Flights from Gulfport-Biloxi Regional Airport to Key West International Airport via Charlotte
- Ave. Duration
- 7h 12m
- When
- Every day
- Estimated price
- $140–700
Flights from Gulfport-Biloxi Regional Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 47m
- When
- Every day
- Estimated price
- $160–750
Flights from Northwest Florida Beaches International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $120–650
Flights from Northwest Florida Beaches International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $160–750
- Website
- delta.com
Flights from Mobile Regional Airport to Key West International Airport via Atlanta
- Ave. Duration
- 6h 38m
- When
- Every day
- Estimated price
- $100–600
Flights from Destin–Fort Walton Beach Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $100–550
Flights from Pensacola International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $120–650
Flights from Gulfport-Biloxi Regional Airport to Key West International Airport via Atlanta
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $110–600
Flights from Northwest Florida Beaches International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $100–550
- Website
- united.com
Flights from Mobile Regional Airport to Key West International Airport via Houston
- Ave. Duration
- 5h 53m
- When
- Saturday
- Estimated price
- $130–650
Flights from Gulfport-Biloxi Regional Airport to Key West International Airport via Houston
- Ave. Duration
- 7h 53m
- When
- Saturday
- Estimated price
- $140–700
Flights from Northwest Florida Beaches International Airport to Key West International Airport via Houston
- Ave. Duration
- 8h 23m
- When
- Saturday
- Estimated price
- $140–700
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Mobile to Fort Myers
- Ave. Duration
- 12h 4m
- Frequency
- Once daily
- Estimated price
- $110–140
- Schedules at
- omnibusexpress.com
Bus from Mobile to Crestview
- Ave. Duration
- 1h 43m
- Frequency
- Once daily
- Estimated price
- $45–65
- Schedules at
- omnibusexpress.com
Bus from Mobile to Gulfport
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- $45–60
- Schedules at
- omnibusexpress.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Mobile Bus Station to Pensacola Airport
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $25–55
- Website
- https://www.greyhound.com/
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Love's Travel Stop - Loxley to Whataburger - Defuniak Springs
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
- Ave. Duration
- 51 min
- Estimated price
- $100–130
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