There are 7 ways to get from Mobile to Key West by train, plane, bus, ferry, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Gulfport-Biloxi Regional Airport, fly
best- Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain
- Fly from Gulfport-Biloxi Regional Airport (GPT) to Key West International Airport (EYW)plane GPT - EYW
7h 53m$130–484Fly from Mobile Regional Airport
cheapest- Fly from Mobile Regional Airport (MOB) to Key West International Airport (EYW)plane MOB - EYW
7h 30m$83–358Bus, ferry
- Take the bus from Mobile to Fort Myersbus Houston
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry Fort Myers Beach
17h 30m$287–330Drive 858.7 mi
- Drive from Mobile to Key Westcar 858.7 mi
15h 29m$157–227Bus to Destin–Fort Walton Beach Airport, fly
- Take the bus from Mobile to Crestviewbus
- Fly from Destin–Fort Walton Beach Airport (VPS) to Key West International Airport (EYW)plane VPS - EYW
7h 20m$165–439Bus to Pensacola International Airport, fly
- Take the bus from Mobile Bus Station to Pensacola Airportbus
- Fly from Pensacola International Airport (PNS) to Key West International Airport (EYW)plane PNS - EYW
7h 44m$290–729Train to Louis Armstrong New Orleans International Airport, fly
- Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain
- Fly from Louis Armstrong New Orleans International Airport (MSY) to Key West International Airport (EYW)plane MSY - EYW
10h 6m$118–499
Gulfport-Biloxi Regional Airport (GPT) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Mobile to Key West is to drive which costs $150 - $230 and takes 15h 29m.
The fastest way to get from Mobile to Key West is to bus and fly which takes 7h 20m and costs $160 - $440.
The distance between Mobile and Key West is 685 miles. The road distance is 863.7 miles.
The best way to get from Mobile to Key West without a car is to bus and ferry which takes 17h 30m and costs $280 - $330.
It takes approximately 7h 53m to get from Mobile to Key West, including transfers.
Key West is 1h ahead of Mobile. It is currently 1:10 AM in Mobile and 2:10 AM in Key West.
Yes, the driving distance between Mobile to Key West is 864 miles. It takes approximately 15h 29m to drive from Mobile to Key West.
There are 973+ hotels available in Key West.
What companies run services between Mobile, AL, USA and Key West, FL, USA?
Delta and American Airlines fly from Mobile Regional Airport (MOB) to Key West International Airport (EYW) 5 times a day.
- Website
- delta.com
Flights from Gulfport-Biloxi Regional Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $85–410
Flights from Mobile Regional Airport to Key West International Airport via Atlanta
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $70–350
Flights from Destin–Fort Walton Beach Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $65–340
Flights from Pensacola International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $60–300
Flights from Louis Armstrong New Orleans International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $95–450
- Website
- aa.com
Flights from Gulfport-Biloxi Regional Airport to Key West International Airport via Charlotte
- Ave. Duration
- 8h 9m
- When
- Every day
- Estimated price
- $100–460
Flights from Gulfport-Biloxi Regional Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 10h 17m
- When
- Every day
- Estimated price
- $120–550
Flights from Mobile Regional Airport to Key West International Airport via Charlotte
- Ave. Duration
- 7h 51m
- When
- Every day
- Estimated price
- $85–400
Flights from Destin–Fort Walton Beach Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 12m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $55–300
Flights from Destin–Fort Walton Beach Airport to Key West International Airport via Charlotte
- Ave. Duration
- 7h 54m
- When
- Every day
- Estimated price
- $85–390
Flights from Pensacola International Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $45–260
Flights from Pensacola International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 6h 37m
- When
- Every day
- Estimated price
- $75–340
Flights from Pensacola International Airport to Key West International Airport via Reagan Washington
- Ave. Duration
- 6h 51m
- When
- Saturday
- Estimated price
- $100–430
Flights from Pensacola International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 52m
- When
- Every day
- Estimated price
- $95–400
Flights from Louis Armstrong New Orleans International Airport to Key West International Airport via Miami
- Ave. Duration
- 6h 3m
- When
- Every day
- Estimated price
- $75–400
Flights from Louis Armstrong New Orleans International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 6h 9m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–550
Flights from Louis Armstrong New Orleans International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 52m
- When
- Every day
- Estimated price
- $120–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Mobile Amtrak Sta to Gulfport Amtrak Sta
- Ave. Duration
- 1h 39m
- Frequency
- Twice daily
- Estimated price
- $19–45
- Website
- Amtrak
Train from Mobile, AL to New Orleans, LA - Union Passenger Terminal
- Ave. Duration
- 3h 43m
- Frequency
- Twice daily
- Estimated price
- $30–85
- Website
- Amtrak
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- Omnibus Express
Bus from Mobile to Fort Myers
- Ave. Duration
- 12h 4m
- Frequency
- Once daily
- Estimated price
- $110–140
- Schedules at
- Omnibus Express
Bus from Mobile to Crestview
- Ave. Duration
- 1h 43m
- Frequency
- Once daily
- Estimated price
- $45–65
- Schedules at
- Omnibus Express
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Mobile Bus Station to Pensacola Airport
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $8–17
- Website
- Greyhound
- Phone
- +1 239-463-5733
- Website
- Key West Express
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- Key West Express
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