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How to get fromMobile to Key Westby plane, bus, ferry, car, or train

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There are 5 ways to get from Mobile to Key West by plane, bus, ferry, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mobile Regional Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Key West International Airport (EYW)plane plane MOB - EYW
    4h 37m
    $118–430

  2. Bus to Pensacola International Airport, fly

    cheapest
    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Key West International Airport (EYW)plane plane PNS - EYW
    6h 58m
    $77–339

  3. Bus, ferry

    1. Take the bus from Mobile to Fort Myersbus bus Houston
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    17h 30m
    $287–330

  4. Drive  858.7 mi

    1. Drive from Mobile to Key Westcar car 858.7 mi
    15h 29m
    $157–227

  5. Train to Gulfport-Biloxi Regional Airport, fly

    1. Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Key West International Airport (EYW)plane plane GPT - EYW
    8h 7m
    $140–482

Mobile Regional Airport (MOB) to Key West International Airport (EYW) flights

Calendar20Weekly Planes
Duration5h 19mAverage Duration
Ticket$76Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mobile to Key West.ExpandLaunch map view
  • Distance: 595.5 mi
  • Duration: 4h 37m

What companies run services between Mobile, AL, USA and Key West, FL, USA?

Delta and American Airlines fly from Mobile Regional Airport (MOB) to Key West International Airport (EYW) 3 times a day.

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