Rome2Rio

How to get fromMobile to Durhamby plane, bus (Flixbus), train (Amtrak), car, train, bus, or bus (Greyhound)

Find Transport to Durham

See all options

There are 8 ways to get from Mobile to Durham by plane, bus (Flixbus), train (Amtrak), car, train, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mobile Regional Airport to Raleigh-Durham International Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Raleigh-Durham International Airport (RDU)plane plane MOB - RDU
    5h 30m
    $123–503

  2. Bus via Winston-Salem (Greyhound)

    cheapest
    1. Take the bus from Mobile Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Durhambus bus
    17h 1m
    $114–181

  3. Bus

    1. Take the bus from Mobile to Atlantabus bus Houston
    2. Take the bus from Atlanta Downtown to Durhambus bus FlixBus N2470
    15h 4m
    $167–232

  4. Train (Amtrak)

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Greensborotrain train
    3. Take the train from Greensboro to Durham Amtrak Stationtrain train
    27h 56m
    $264–612

  5. Drive  708.8 mi

    1. Drive from Mobile to Durhamcar car 708.8 mi
    11h 52m
    $130–187

  6. Fly Mobile Regional Airport to Piedmont Triad International Airport, train

    1. Fly from Mobile Regional Airport (MOB) to Piedmont Triad International Airport (GSO)plane plane MOB - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain train
    6h 10m
    $205–857

  7. Bus to Pensacola International Airport, fly to Raleigh-Durham International Airport

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Raleigh-Durham International Airport (RDU)plane plane PNS - RDU
    6h 36m
    $135–471

  8. Train to Gulfport-Biloxi Regional Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Raleigh-Durham International Airport (RDU)plane plane GPT - RDU
    8h 4m
    $134–615

Mobile to Durham by bus (Greyhound)

Calendar7Weekly Buses
Duration17h 1mAverage Duration
Ticket$114Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Mobile to Durham.ExpandLaunch map view
  • Distance: 682.9 mi
  • Duration: 5h 30m

What companies run services between Mobile, AL, USA and Durham, NC, USA?

Delta, American Airlines, and United Airlines fly from Mobile Regional Airport (MOB) to Raleigh-Durham International Airport (RDU) every 2 hours. Alternatively, you can take a bus from Mobile to Durham via Mobile, Atlanta, Doraville Station, Civic Center Station, and Atlanta Downtown in around 15h 4m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There