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How to get fromMobile to Chicagoby bus, plane, train (Amtrak), bus (Greyhound, Amtrak), car, or train

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There are 9 ways to get from Mobile to Chicago by bus, plane, train (Amtrak), bus (Greyhound, Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pensacola International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Chicago Midway International Airport (MDW)plane plane PNS - MDW
    6h 38m
    $97–484

  2. Fly Mobile Regional Airport to Chicago O'Hare International Airport

    cheapest
    1. Fly from Mobile Regional Airport (MOB) to Chicago O'Hare International Airport (ORD)plane plane MOB - ORD
    8h 56m
    $79–391

  3. Train (Amtrak)

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train Mobile / ...
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train City of New Orleans
    24h 13m
    $290–689

  4. Bus

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Chicago Union Stationbus bus
    24h 37m
    $158–314

  5. Drive 857.2 mi

    1. Drive from Mobile to Chicagocar car 857.2 mi
    15h 44m
    $157–226

  6. Fly Mobile Regional Airport to Chicago Midway International Airport

    1. Fly from Mobile Regional Airport (MOB) to Chicago Midway International Airport (MDW)plane plane MOB - MDW
    8h 17m
    $97–480

  7. Bus to Pensacola International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Chicago O'Hare International Airport (ORD)plane plane PNS - ORD
    7h 12m
    $107–464

  8. Bus to Destin–Fort Walton Beach Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Chicago O'Hare International Airport (ORD)plane plane VPS - ORD
    6h 38m
    $171–501

  9. Train to Louis Armstrong New Orleans International Airport, fly to Chicago Midway International Airport

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Fly from Louis Armstrong New Orleans International Airport (MSY) to Chicago Midway International Airport (MDW)plane plane MSY - MDW
    9h 1m
    $129–649

Mobile to Chicago by bus

Calendar7Weekly Buses
Duration24h 37mAverage Duration
Ticket$158Cheapest Price
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Questions & Answers

What companies run services between Mobile, AL, USA and Chicago, IL, USA?

You can take a train from Mobile, AL to Chicago Union Station via New Orleans Union Passenger Terminal in around 24h 13m. Alternatively, you can take a bus from St Joseph SB Near St Louis St to Chicago Union Station via Govt WB Across from Greyhound, Mobile Bus Station, Montgomery Intermodal Center, and Indianapolis Union Station in around 24h 37m.

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