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How to get fromMobile to Chicagoby plane, bus (Greyhound, Amtrak), train (Amtrak), car, or bus

Find Transport to Chicago

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There are 7 ways to get from Mobile to Chicago by plane, bus (Greyhound, Amtrak), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mobile Regional Airport to Chicago Midway International Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Chicago Midway International Airport (MDW)plane plane MOB - MDW
    5h 50m
    $119–472

  2. Bus to Pensacola International Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Chicago O'Hare International Airport (ORD)plane plane PNS - ORD
    6h 47m
    $71–340

  3. Bus

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Chicago Union Stationbus bus
    23h 23m
    $150–237

  4. Train (Amtrak)

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train Mobile / ...
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train City of New Orleans
    24h 13m
    $270–627

  5. Drive  857.2 mi

    1. Drive from Mobile to Chicagocar car 857.2 mi
    15h 44m
    $157–226

  6. Fly Mobile Regional Airport to Chicago O'Hare International Airport

    1. Fly from Mobile Regional Airport (MOB) to Chicago O'Hare International Airport (ORD)plane plane MOB - ORD
    5h 46m
    $104–402

  7. Bus to Pensacola International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Chicago Midway International Airport (MDW)plane plane PNS - MDW
    7h 46m
    $81–400

Mobile to Chicago by bus

Calendar7Weekly Buses
Duration23h 23mAverage Duration
Ticket$150Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mobile to Chicago.ExpandLaunch map view
  • Distance: 792.1 mi
  • Duration: 5h 50m

What companies run services between Mobile, AL, USA and Chicago, IL, USA?

Delta, American Airlines, and two other airlines fly from Mobile Regional Airport (MOB) to Chicago Midway International Airport (MDW) 3 times a day. Alternatively, you can take a bus from Govt WB and Joachim St to Chicago Union Station via Govt WB Across from Greyhound, Mobile Bus Station, Montgomery Intermodal Center, and Indianapolis Union Station in around 23h 23m.

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