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How to get fromMobile to Chicagoby bus, plane, bus (Greyhound, Flixbus), train or car

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There are 9 ways to get from Mobile to Chicago by bus, plane, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pensacola International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from Mobile Bus Station to Pensacola Airportbus
    2. Fly from Pensacola International Airport (PNS) to Chicago Midway International Airport (MDW)planePNS - MDW
    6h 38m
    $117–533

  2. Fly Mobile Regional Airport to Chicago O'Hare International Airport

    cheapest
    1. Fly from Mobile Regional Airport (MOB) to Chicago O'Hare International Airport (ORD)planeMOB - ORD
    9h 22m
    $68–341

  3. Bus

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus
    2. Take the bus from Montgomery Intermodal Center to Nashville Bus Stationbus
    3. Take the bus from Nashville Bus Station to Chicago Bus Stationbus
    21h 37m
    $170–413

  4. Bus, train

    1. Take the bus from Mobile Bus Station to New Orleans Bus StationbusGreyhound US0602
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union StationtrainCity of New Orleans
    24h 46m
    $173–643

  5. Drive 857 mi

    1. Drive from Mobile to Chicagocar857 mi
    15h 53m
    $157–226

  6. Bus to Pensacola International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus
    2. Fly from Pensacola International Airport (PNS) to Chicago O'Hare International Airport (ORD)planePNS - ORD
    7h 3m
    $197–383

  7. Fly Mobile Regional Airport to Chicago Midway International Airport

    1. Fly from Mobile Regional Airport (MOB) to Chicago Midway International Airport (MDW)planeMOB - MDW
    8h 44m
    $88–451

  8. Drive to Birmingham–Shuttlesworth International Airport, fly to Chicago Midway International Airport

    1. Drive from Mobile to Birmingham-Airport-BHMcar
    2. Fly from Birmingham–Shuttlesworth International Airport (BHM) to Chicago Midway International Airport (MDW)planeBHM - MDW
    6h 48m
    $160–724

  9. Bus to Destin–Fort Walton Beach Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Mobile to Crestviewbus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Chicago O'Hare International Airport (ORD)planeVPS - ORD
    6h 38m
    $161–451

Mobile to Chicago by bus

Calendar7Weekly Buses
Duration21h 37mAverage Duration
Ticket$170Cheapest Price
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Questions & Answers

What companies run services between Mobile, AL, USA and Chicago, IL, USA?

You can take a bus from St Joseph SB Near St Louis St to Chicago Bus Station via Govt WB Across from Greyhound, Mobile Bus Station, Montgomery Intermodal Center, and Nashville Bus Station in around 21h 37m. Alternatively, Delta, American Airlines, and United Airlines fly from Mobile Regional Airport (MOB) to Chicago O'Hare International Airport (ORD) hourly.

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