Rome2Rio

How to get fromMobile to Chicagoby plane, bus (Greyhound), train (Amtrak), car, bus, or train

Find Transport to Chicago

See all options

There are 9 ways to get from Mobile to Chicago by plane, bus (Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mobile Regional Airport to Chicago Midway International Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Chicago Midway International Airport (MDW)plane plane MOB - MDW
    9h 43m
    $87–412

  2. Bus to Pensacola International Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Chicago O'Hare International Airport (ORD)plane plane PNS - ORD
    7h 7m
    $66–312

  3. Bus (Greyhound)

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Chicago Bus Stationbus bus
    23h 52m
    $143–283

  4. Train (Amtrak)

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train Mobile / ...
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train City of New Orleans
    24h 13m
    $320–740

  5. Drive 857.2 mi

    1. Drive from Mobile to Chicagocar car 857.2 mi
    15h 44m
    $157–226

  6. Fly Mobile Regional Airport to Chicago O'Hare International Airport

    1. Fly from Mobile Regional Airport (MOB) to Chicago O'Hare International Airport (ORD)plane plane MOB - ORD
    8h 41m
    $75–353

  7. Bus to Pensacola International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Chicago Midway International Airport (MDW)plane plane PNS - MDW
    8h 13m
    $76–362

  8. Bus to Destin–Fort Walton Beach Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Chicago O'Hare International Airport (ORD)plane plane VPS - ORD
    6h 40m
    $166–461

  9. Train to Louis Armstrong New Orleans International Airport, fly to Chicago Midway International Airport

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Fly from Louis Armstrong New Orleans International Airport (MSY) to Chicago Midway International Airport (MDW)plane plane MSY - MDW
    8h 59m
    $134–600

Mobile to Chicago by bus (Greyhound)

Calendar14Weekly Buses
Duration23h 52mAverage Duration
Ticket$143Cheapest Price
See schedules

Questions & Answers

Map of how to get from Mobile to Chicago.ExpandLaunch map view
  • Distance: 801.4 mi
  • Duration: 9h 43m

What companies run services between Mobile, AL, USA and Chicago, IL, USA?

Delta, American Airlines, and two other airlines fly from Mobile Regional Airport (MOB) to Chicago Midway International Airport (MDW) 4 times a day. Alternatively, you can take a bus from St Joseph SB Near St Louis St to Chicago Bus Station via Govt WB Across from Greyhound, Mobile Bus Station, Montgomery Intermodal Center, and Indianapolis Union Station in around 23h 52m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers