Rome2Rio

How to get fromMobile to Buffaloby plane, bus (Greyhound), train (Amtrak), car, train, bus, or bus (Greyhound, Flixbus)

Find Transport to Buffalo

See all options

There are 9 ways to get from Mobile to Buffalo by plane, bus (Greyhound), train (Amtrak), car, train, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mobile Regional Airport to Buffalo Niagara International Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Buffalo Niagara International Airport (BUF)plane plane MOB - BUF
    9h 6m
    $139–664

  2. Bus to Pensacola International Airport, fly to Buffalo Niagara International Airport

    cheapest
    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Buffalo Niagara International Airport (BUF)plane plane PNS - BUF
    9h 12m
    $130–670

  3. Bus

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Toledo Bus Stopbus bus
    3. Take the bus from Toledo to Clevelandbus bus
    4. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    30h 52m
    $175–394

  4. Train (Amtrak)

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    36h 57m
    $402–1,079

  5. Drive  1,125.9 mi

    1. Drive from Mobile to Buffalocar car 1,125.9 mi
    19h 58m
    $206–297

  6. Train to Gulfport-Biloxi Regional Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Buffalo Niagara International Airport (BUF)plane plane GPT - BUF
    8h 57m
    $195–863

  7. Bus to Destin–Fort Walton Beach Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF)plane plane VPS - BUF
    8h 45m
    $230–779

  8. Fly Mobile Regional Airport to Rochester, bus

    1. Fly from Mobile Regional Airport (MOB) to Rochester (ROC)plane plane MOB - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    10h 13m
    $216–935

  9. Bus via Akron

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Toledo Bus Stopbus bus
    3. Take the bus from Toledo Bus Stop to Robert K Pfaff Transit Center - Akronbus bus
    4. Take the bus from Akron to Buffalobus bus
    32h 52m
    $188–389

Mobile to Buffalo by bus

Calendar7Weekly Buses
Duration30h 52mAverage Duration
Ticket$175Cheapest Price
See schedules

Questions & Answers

Map of how to get from Mobile to Buffalo.ExpandLaunch map view
  • Distance: 1,027.5 mi
  • Duration: 9h 6m

What companies run services between Mobile, AL, USA and Buffalo, NY, USA?

Delta, United Airlines, and American Airlines fly from Mobile Regional Airport (MOB) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a bus from St Joseph SB Near St Louis St to Buffalo, NY via Govt WB Across from Greyhound, Mobile Bus Station, Montgomery Intermodal Center, Toledo, and Cleveland, OH in around 30h 52m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers