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How to get fromMobile to Buffaloby plane, bus (Greyhound), train (Amtrak), car, train, bus, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Mobile to Buffalo by plane, bus (Greyhound), train (Amtrak), car, train, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mobile Regional Airport to Buffalo Niagara International Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Buffalo Niagara International Airport (BUF)plane plane MOB - BUF
    9h
    $236–1,122

  2. Fly Mobile Regional Airport to Rochester, bus

    cheapest
    1. Fly from Mobile Regional Airport (MOB) to Rochester (ROC)plane plane MOB - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    10h 38m
    $152–632

  3. Bus via Cleveland

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Toledo Bus Stopbus bus
    3. Take the bus from Toledo to Clevelandbus bus
    4. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    31h 27m
    $186–417

  4. Train (Amtrak)

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    36h 57m
    $459–1,094

  5. Drive 1,125.8 mi

    1. Drive from Mobile to Buffalocar car 1,125.8 mi
    19h 58m
    $206–297

  6. Train to Gulfport-Biloxi Regional Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Buffalo Niagara International Airport (BUF)plane plane GPT - BUF
    8h 45m
    $341–1,492

  7. Bus to Destin–Fort Walton Beach Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF)plane plane VPS - BUF
    8h 53m
    $324–1,254

  8. Bus to Pensacola International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Buffalo Niagara International Airport (BUF)plane plane PNS - BUF
    9h 25m
    $245–1,247

  9. Bus

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Toronto Pearson Airportbus bus
    4. Take the bus from Toronto Pearson Airport to Buffalobus bus
    37h 12m
    $210–409

Mobile to Buffalo by bus

Calendar7Weekly Buses
Duration31h 27mAverage Duration
Ticket$186Cheapest Price
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Questions & Answers

What companies run services between Mobile, AL, USA and Buffalo, NY, USA?

American Airlines, Delta, and United Airlines fly from Mobile Regional Airport (MOB) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a bus from St Joseph SB Near St Louis St to Buffalo, NY via Govt WB Across from Greyhound, Mobile Bus Station, Montgomery Intermodal Center, Toledo, and Cleveland, OH in around 31h 27m.

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