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How to get fromMobile to Buffaloby plane, bus (Greyhound), bus, train or car

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There are 9 ways to get from Mobile to Buffalo by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mobile Regional Airport to Buffalo Niagara International Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Buffalo Niagara International Airport (BUF)plane plane MOB - BUF
    9h 50m
    $254–1,320

  2. Fly Mobile Regional Airport to Rochester, bus

    cheapest
    1. Fly from Mobile Regional Airport (MOB) to Rochester (ROC)plane plane MOB - ROC
    2. Take the bus from Rochester, NY to Buffalo, NYbus bus
    11h 50m
    $161–808

  3. Bus

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Cleveland Bus Stationbus bus
    4. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    28h 7m
    $185–440

  4. Bus, train via Chicago

    1. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    37h 30m
    $207–627

  5. Drive 1,125.8 mi

    1. Drive from Mobile to Buffalocar car 1,125.8 mi
    19h 59m
    $206–297

  6. Bus to Destin–Fort Walton Beach Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF)plane plane VPS - BUF
    8h 39m
    $343–1,506

  7. Bus to Pensacola International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Buffalo Niagara International Airport (BUF)plane plane PNS - BUF
    9h 11m
    $300–1,533

  8. Bus to Gulfport-Biloxi Regional Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Mobile to Gulfportbus bus
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Buffalo Niagara International Airport (BUF)plane plane GPT - BUF
    10h 7m
    $393–1,708

  9. Bus, train

    1. Take the bus from Mobile to Wildwoodbus bus
    2. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    3. Take the train from Jacksonville to Pittsburgh Amtrak Stationtrain train
    4. Take the bus from Pittsburgh to Buffalobus bus
    47h 49m

Mobile to Buffalo by bus

Calendar7Weekly Buses
Duration28h 7mAverage Duration
Ticket$185Cheapest Price
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Questions & Answers

What companies run services between Mobile, AL, USA and Buffalo, NY, USA?

American Airlines, United Airlines, and Delta fly from Mobile Regional Airport (MOB) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a bus from St Joseph SB Near St Louis St to Buffalo, NY via Govt WB Across from Greyhound, Mobile Bus Station, Montgomery Intermodal Center, Nashville Bus Station, Cleveland Bus Station, and Cleveland, OH in around 28h 7m.

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