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How to get fromMobile to Buffaloby plane, bus (Greyhound), bus, train or car

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There are 9 ways to get from Mobile to Buffalo by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mobile Regional Airport to Buffalo Niagara International Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Buffalo Niagara International Airport (BUF)planeMOB - BUF
    9h 33m
    $255–1,386

  2. Fly Mobile Regional Airport to Rochester, bus

    cheapest
    1. Fly from Mobile Regional Airport (MOB) to Rochester (ROC)planeMOB - ROC
    2. Take the bus from Rochester, NY to Buffalo, NYbus
    11h 37m
    $155–791

  3. Bus

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus
    2. Take the bus from Montgomery Intermodal Center to Nashville Bus Stationbus
    3. Take the bus from Nashville Bus Station to Cleveland Bus Stationbus
    4. Take the bus from Cleveland, OH to Buffalo, NYbus
    28h 7m
    $193–463

  4. Bus, train via Chicago

    1. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain
    37h 30m
    $227–878

  5. Drive 1,148 mi

    1. Drive from Mobile to Buffalocar1,148 mi
    18h 55m
    $210–303

  6. Bus to Destin–Fort Walton Beach Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Mobile to Crestviewbus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF)planeVPS - BUF
    8h 50m
    $353–1,506

  7. Bus to Pensacola International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus
    2. Fly from Pensacola International Airport (PNS) to Buffalo Niagara International Airport (BUF)planePNS - BUF
    9h 7m
    $309–1,538

  8. Bus to Gulfport-Biloxi Regional Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Mobile to Gulfportbus
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Buffalo Niagara International Airport (BUF)planeGPT - BUF
    9h 41m
    $413–1,708

  9. Bus, train

    1. Take the bus from Mobile to Wildwoodbus
    2. Take the bus from Wildwood Amtrak Station to Jacksonvillebus
    3. Take the train from Jacksonville to Pittsburgh Amtrak Stationtrain
    4. Take the bus from Pittsburgh to Buffalobus
    47h 49m

Mobile to Buffalo by bus

Calendar7Weekly Buses
Duration28h 7mAverage Duration
Ticket$193Cheapest Price
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Questions & Answers

What companies run services between Mobile, AL, USA and Buffalo, NY, USA?

Delta, American Airlines, and United Airlines fly from Mobile Regional Airport (MOB) to Buffalo Niagara International Airport (BUF) 5 times a day. Alternatively, you can take a bus from St Joseph SB Near St Louis St to Buffalo, NY via Govt WB Across from Greyhound, Mobile Bus Station, Montgomery Intermodal Center, Nashville Bus Station, Cleveland Bus Station, and Cleveland, OH in around 28h 7m.

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