There are 6 ways to get from Mitchell to Des Moines by bus, car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Mitchell to Sioux Falls
- Take the bus from Sioux Falls to Omaha
- Take the bus from Omaha to Des Moines
8h 40m$59–211Bus via Des Moines #2
cheapest- Take the bus from Mitchell to Sioux Falls
- Take the bus from Sioux Falls to Omaha
- Take the bus from Omaha, NE to Des Moines
8h 55m$52–186Drive 351.7 mi
- Drive from Mitchell to Des Moines351.7 mi
5h 25m$65–93Bus to Sioux Falls, fly
- Take the bus from Mitchell to Sioux Falls
- Fly from Sioux Falls (FSD) to Des Moines (DSM)FSD - DSM
6h 1m$135–687Bus via Des Moines
- Take the bus from Mitchell to Sioux Falls
- Take the bus from Sioux Falls to Omaha
- Take the bus from Omaha to Des Moines
8h 45m$59–211Drive to Aberdeen Regional Airport, fly
- Drive from Mitchell to Aberdeen Regional Airport (ABR)
- Fly from Aberdeen Regional Airport (ABR) to Des Moines (DSM)ABR - DSM
8h 26m$144–710
Mitchell to Des Moines by bus
Questions & Answers
The cheapest way to get from Mitchell to Des Moines is to drive which costs $60 - $95 and takes 5h 25m.
The fastest way to get from Mitchell to Des Moines is to drive which takes 5h 25m and costs $60 - $95.
No, there is no direct bus from Mitchell to Des Moines. However, there are services departing from Mitchell and arriving at Des Moines via Sioux Falls and Omaha. The journey, including transfers, takes approximately 8h 40m.
The distance between Mitchell and Des Moines is 395 miles. The road distance is 353.8 miles.
The best way to get from Mitchell to Des Moines without a car is to bus which takes 8h 40m and costs $55 - $220.
It takes approximately 8h 40m to get from Mitchell to Des Moines, including transfers.
Mitchell to Des Moines bus services, operated by Jefferson Lines, depart from Mitchell station.
Mitchell to Des Moines bus services, operated by Jefferson Lines, arrive at Sioux Falls station.
Yes, the driving distance between Mitchell to Des Moines is 354 miles. It takes approximately 5h 25m to drive from Mitchell to Des Moines.
There are 231+ hotels available in Des Moines.
What companies run services between Mitchell, SD, USA and Des Moines, IA, USA?
You can take a bus from Mitchell to Des Moines via Sioux Falls and Omaha in around 8h 40m.
- Website
- united.com
Flights from Sioux Falls to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 44m
- When
- Every day
- Estimated price
- $130–700
Flights from Sioux Falls to Des Moines via Denver
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $170–850
- Website
- delta.com
Flights from Sioux Falls to Des Moines via Minneapolis
- Ave. Duration
- 4h 33m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $100–600
Flights from Aberdeen Regional Airport to Des Moines via Minneapolis
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $100–650
- Website
- aa.com
Flights from Sioux Falls to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $130–700
Flights from Sioux Falls to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 19m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $200–950
- Website
- allegiantair.com
Flights from Sioux Falls to Des Moines via St. Petersburg
- Ave. Duration
- 7h 22m
- When
- Sunday
- Estimated price
- $310–1,300
Flights from Sioux Falls to Des Moines via Phoenix esa Gateway
- Ave. Duration
- 7h 54m
- When
- Thursday
- Estimated price
- $290–1,200
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Mitchell to Sioux Falls
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $6–55
- Book at
- https://www.jeffersonlines.com
Bus from Sioux Falls to Omaha
- Ave. Duration
- 3h 35m
- Frequency
- Once daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Omaha to Des Moines
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $35–70
- Website
- https://burlingtontrailways.com
- Saver Fares
- $35–55
- Flexible Fares
- $45–70
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Omaha, NE to Des Moines
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $28–45
- Website
- https://www.greyhound.com/
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