There are 8 ways to get from Missouri to Indiana by bus, plane, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Line 34 bus to St. Louis, fly to Chicago Midway, train  •  4 h 42 min

  1. Take the line 34 bus from 4375 Rider Trail North Sb to North Hanley Transit Center
  2. Fly from St. Louis (STL) to Chicago Midway (MDW) STL - MDW
  3. Take the train from Van Buren St. to East Chicago

$168 - $361

Cheapest option

Line 34 bus to St. Louis, fly to Owensboro, bus  •  5 h 5 min

  1. Take the line 34 bus from 4375 Rider Trail North Sb to North Hanley Transit Center
  2. Fly from St. Louis (STL) to Owensboro (OWB) STL - OWB
  3. Take the bus from Owensboro, KY to Evansville

$58 - $98

6 alternative options

Fly Kansas City to Indianapolis  •  4 h 24 min

  1. Fly from Kansas City (MCI) to Indianapolis (IND) MCI - IND

$164 - $304

Fly St. Louis to Chicago O'Hare, bus  •  4 h 41 min

  1. Fly from St. Louis (STL) to Chicago O'Hare (ORD) STL - ORD
  2. Take the bus from Chicago O'Hare Airport to Highland, IN

$116 - $281

Bus via St Louis, Mo  •  10 h 36 min

  1. Take the bus from Kansas City, Mo to St Louis, Mo
  2. Take the bus from St Louis, Mo to Champaign, Il
  3. Take the bus from Champaign, IL to Indianapolis, IN

$82 - $173

Bus  •  12 h 16 min

  1. Take the bus from Kansas City, Mo to Terre Haute, In 1684
  2. Take the bus from Terre Haute, IN to Indianapolis, IN Terre Haute

$65 - $138

Train  •  13 h 16 min

  1. Take the train from Kansas City Amtrak to Chicago Union Station Southwest Chief
  2. Take the train from Chicago Union Station to Indianapolis Amtrak Hoosier State / ...

$109 - $282

Drive  •  8 h 6 min

  1. Drive from Kansas City to Indianapolis 484.9 miles

$45 - $70

Questions & Answers

No, there is no direct bus from Missouri to Indiana. However, there are services departing from Kansas City, Mo and arriving at Indianapolis, IN via St Louis, Mo and Champaign, IL. The journey, including transfers, takes approximately 10 h 36 min.

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No, there is no direct train from Missouri to Indiana. However, there are services departing from Kansas City Amtrak and arriving at Indianapolis Amtrak via Chicago Union Station. The journey, including transfers, takes approximately 13 h 16 min.

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The distance between Missouri and Indiana is 359 miles. The road distance is 484.9 miles.

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The best way to get from Missouri to Indiana without a car is to bus which takes 10 h 36 min and costs .

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It takes approximately 4 h 42 min to get from Missouri to Indiana, including transfers.

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Missouri to Indiana bus services, operated by Greyhound USA, depart from Kansas City, Mo station.

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Missouri to Indiana train services, operated by Amtrak, depart from Kansas City Amtrak station.

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The best way to get from Missouri to Indiana is to fly which takes 4 h 24 min and costs . Alternatively, you can bus, which costs and takes 10 h 36 min, you could also train, which costs and takes 13 h 16 min.

Mode details

The quickest flight from St. Louis Airport to Chicago Midway Airport is the direct flight which takes 1 h.

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Missouri to Indiana bus services, operated by Burlington Trailways, arrive at Indianapolis, IN station.

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Map of how to get from Missouri to Indiana.
Launch map view
  • Distance: 359.1 miles
  • Duration: 4 h 42 min

What companies run services between Missouri, USA and Indiana, USA?

Southwest Airlines and American Airlines fly from Kansas City to Indianapolis 3 times a day. Alternatively, you can take a bus from Kansas City to Indianapolis via St Louis, Mo, Champaign, Il, and Champaign, IL in around 10 h 36 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from St. Louis to Chicago Midway
Ave. Duration
1 h 2 min
When
Every day
Estimated price
$160 - $550
Flights from Kansas City to Indianapolis
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$340 - $650
American Airlines
Website
aa.com
Flights from Kansas City to Indianapolis via Chicago O'Hare
Ave. Duration
3 h 40 min
When
Every day
Estimated price
$290 - $600
Flights from St. Louis to Chicago O'Hare
Ave. Duration
1 h 22 min
When
Every day
Estimated price
$120 - $550
Flights from St. Louis to Owensboro
Ave. Duration
1 h 9 min
When
Every day
Estimated price
$24 - $110
United Airlines
Website
united.com
Flights from St. Louis to Chicago O'Hare
Ave. Duration
1 h 22 min
When
Every day
Estimated price
$120 - $650
Cape Air
Website
capeair.com
Flights from St. Louis to Chicago O'Hare via Decatur
Ave. Duration
3 h 3 min
When
Thursday and Friday
Estimated price
$130 - $380
Flights from St. Louis to Owensboro
Ave. Duration
1 h 9 min
When
Every day
Estimated price
$24 - $110
Train operators
South Shore Line
Phone
+1 219-926-5744
Website
nictd.com
Train from Van Buren St. to East Chicago
Ave. Duration
43 min
Frequency
Every 15 minutes
Estimated price
$6 - $7
Schedules at
nictd.com
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Kansas City Amtrak to Chicago Union Station
Ave. Duration
7 h 22 min
Frequency
Twice daily
Estimated price
$65 - $190
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$120 - $180
Business Coach Seat
$130 - $190
Room
$290 - $410
Train from Chicago Union Station to Indianapolis Amtrak
Ave. Duration
4 h 54 min
Frequency
Once daily
Estimated price
$40 - $100
Website
amtrak.com
Coach Seat
$40 - $60
Flexi Coach Seat
$70 - $110
Business Coach Seat
$70 - $100
Room
$200 - $280
Bus operators
Metro St. Louis
Phone
+1 314-982-1400
Website
metrostlouis.org
Bus from 4375 Rider Trail North Sb to North Hanley Transit Center
Ave. Duration
38 min
Frequency
Hourly
Estimated price
$2
Schedules at
metrostlouis.org
bus
Bus from Terminal 2, Chicago, IL - O'Hare Intl Airport to Highland, IN
Ave. Duration
1 h 5 min
Frequency
Hourly
Schedules at
airportsupersaver.com
Book at
airportsupersaver.com
Hoosier Ride
Phone
800-544-2383
Website
hoosierride.com
Bus from Owensboro, KY to Evansville
Ave. Duration
55 min
Frequency
Twice daily
Estimated price
$14 - $19
Book at
hoosierride.com
Bus from Terre Haute, IN to Indianapolis, IN
Ave. Duration
1 h 15 min
Frequency
3 times a day
Estimated price
$19 - $28
Book at
hoosierride.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Kansas City, Mo to St Louis, Mo
Ave. Duration
4 h
Frequency
Hourly
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Bus from St Louis, Mo to Champaign, Il
Ave. Duration
3 h
Frequency
Every 30 minutes
Estimated price
$23 - $55
Website
greyhound.com
Economy
$23 - $35
Flexible
$40 - $55
Bus from Kansas City, Mo to Terre Haute, In
Ave. Duration
9 h 50 min
Frequency
Every 4 hours
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110
Burlington Trailways
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Bus from Champaign-Urbana to Indianapolis
Ave. Duration
3 h 10 min
Frequency
Twice daily
Website
amtrak.com

Want to know more about travelling around United States

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More Questions & Answers

Indiana is 1 h ahead of Missouri. It is currently 6:27 PM in Missouri and 7:27 PM in Indiana.

Missouri to Indiana train services, operated by Amtrak, arrive at Indianapolis Amtrak station.

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Yes, the driving distance between Missouri to Indiana is 485 miles. It takes approximately 8 h 6 min to drive from Missouri to Indiana.

Get driving directions

Southwest Airlines offers flights from St. Louis Airport to Chicago Midway Airport.

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Book your Missouri to Indiana train tickets online with Rome2rio.

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There are 10+ hotels available in Indiana. Prices start at $100 USD per night.

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The best way to get from Missouri to Kansas City Airport is to line 229 bus which takes 52 min and costs .

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