There are 9 ways to get from Missouri to Indiana by bus, plane, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Line 34 bus to St. Louis, fly to Chicago Midway, train  •  4 h 42 min

  1. Take the line 34 bus from 4375 Rider Trail North Sb to North Hanley Transit Center
  2. Fly from St. Louis (STL) to Chicago Midway (MDW) STL - MDW
  3. Take the train from Van Buren St. to East Chicago

$168 - $361

Cheapest option

Line 34 bus to St. Louis, fly to Owensboro, bus  •  5 h 5 min

  1. Take the line 34 bus from 4375 Rider Trail North Sb to North Hanley Transit Center
  2. Fly from St. Louis (STL) to Owensboro (OWB) STL - OWB
  3. Take the bus from Owensboro, KY to Evansville

$58 - $98

7 alternative options

Fly Kansas City to Indianapolis  •  4 h 24 min

  1. Fly from Kansas City (MCI) to Indianapolis (IND) MCI - IND

$164 - $304

Fly St. Louis to Chicago O'Hare, bus  •  4 h 40 min

  1. Fly from St. Louis (STL) to Chicago O'Hare (ORD) STL - ORD
  2. Take the bus from Chicago O'Hare Airport to Highland, IN

$116 - $281

Bus via St Louis, Mo  •  10 h 40 min

  1. Take the bus from Kansas City, Mo to St Louis, Mo
  2. Take the bus from St Louis, Mo to Champaign, Il
  3. Take the bus from Champaign, IL to Indianapolis, IN

$82 - $173

Train, bus  •  12 h 7 min

  1. Take the train from Kansas City Amtrak to Galesburg Amtrak Southwest Chief
  2. Take the bus from Galesburg Amtrak to Indianapolis, IN 1401 / ...

$96 - $212

Bus  •  12 h 14 min

  1. Take the bus from Kansas City, Mo to Terre Haute, In 1684
  2. Take the bus from Terre Haute, IN to Indianapolis, IN 0017 / ...

$60 - $136

Train  •  13 h 20 min

  1. Take the train from Kansas City Amtrak to Chicago Union Station Amtrak Southwest Chief
  2. Take the train from Chicago Union Station Amtrak to Indianapolis Amtrak Hoosier State / ...

$109 - $282

Drive  •  8 h 6 min

  1. Drive from Kansas City to Indianapolis 484.9 miles

$45 - $70

Questions & Answers

The cheapest way to get from Missouri to Indiana is to drive which costs $45 - $70 and takes 8 h 6 min.

More details

The quickest way to get from Missouri to Indiana is to fly which costs $160 - $310 and takes 4 h 24 min.

More details

The distance between Missouri and Indiana is 359 miles. The road distance is 484.9 miles.

Get driving directions

It takes approximately 4 h 42 min to get from Missouri to Indiana, including transfers.

More details

No, there is no direct bus from Missouri to Indiana. However, there are services departing from Kansas City, Mo and arriving at Indianapolis, IN via St Louis, Mo and Champaign, IL. The journey, including transfers, takes approximately 10 h 40 min.

More details

No, there is no direct train from Missouri to Indiana. However, there are services departing from Kansas City Amtrak and arriving at Indianapolis Amtrak via Chicago Union Station Amtrak. The journey, including transfers, takes approximately 13 h 20 min.

More details

What companies run services between Missouri, USA and Indiana, USA?

Southwest Airlines, American Airlines and United Airlines fly from Kansas City to Indianapolis 5 times a day. Alternatively, you can take a bus from Kansas City to Indianapolis via St Louis, Mo, Champaign, Il, and Champaign, IL in around 10 h 40 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from St. Louis to Chicago Midway
Ave. Duration
1 h 3 min
When
Every day
Estimated price
$160 - $550
Flights from Kansas City to Indianapolis
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$340 - $650
American Airlines
Website
aa.com
Flights from Kansas City to Indianapolis via Chicago O'Hare
Ave. Duration
3 h 32 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$290 - $600
Flights from St. Louis to Chicago O'Hare
Ave. Duration
1 h 24 min
When
Every day
Estimated price
$120 - $550
Flights from St. Louis to Owensboro
Ave. Duration
1 h 9 min
When
Every day
Estimated price
$24 - $110
United Airlines
Website
united.com
Flights from Kansas City to Indianapolis via Chicago O'Hare
Ave. Duration
3 h 35 min
When
Monday to Saturday
Estimated price
$280 - $600
Flights from St. Louis to Chicago O'Hare
Ave. Duration
1 h 22 min
When
Every day
Estimated price
$120 - $650
Cape Air
Website
capeair.com
Flights from St. Louis to Owensboro
Ave. Duration
1 h 9 min
When
Every day
Estimated price
$24 - $110
Train operators
South Shore Line
Phone
+1 219-926-5744
Website
nictd.com
Train from Van Buren St. to East Chicago
Ave. Duration
43 min
Frequency
Every 15 minutes
Estimated price
$6 - $7
Schedules at
nictd.com
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Kansas City Amtrak to Galesburg Amtrak
Ave. Duration
4 h 18 min
Frequency
Once daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$85 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Train from Kansas City Amtrak to Chicago Union Station Amtrak
Ave. Duration
7 h 26 min
Frequency
Once daily
Estimated price
$65 - $190
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$120 - $180
Business Coach Seat
$130 - $190
Room
$290 - $410
Train from Chicago Union Station Amtrak to Indianapolis Amtrak
Ave. Duration
4 h 54 min
Frequency
Once daily
Estimated price
$40 - $100
Website
amtrak.com
Coach Seat
$40 - $60
Flexi Coach Seat
$70 - $110
Business Coach Seat
$70 - $100
Room
$200 - $280
Bus operators
Metro St. Louis
Phone
+1 314-982-1400
Website
metrostlouis.org
Bus from 4375 Rider Trail North Sb to North Hanley Transit Center
Ave. Duration
38 min
Frequency
Hourly
Estimated price
$2
Schedules at
metrostlouis.org
bus
Bus from Terminal 2, Chicago, IL - O'Hare Intl Airport to Highland, IN
Ave. Duration
1 h 5 min
Frequency
Hourly
Schedules at
airportsupersaver.com
Book at
airportsupersaver.com
Hoosier Ride
Phone
800-544-2383
Website
hoosierride.com
Bus from Owensboro, KY to Evansville
Ave. Duration
55 min
Frequency
Once daily
Estimated price
$14 - $19
Schedules at
hoosierride.com
Bus from Terre Haute, IN to Indianapolis, IN
Ave. Duration
1 h 15 min
Frequency
Twice daily
Estimated price
$16 - $28
Schedules at
hoosierride.com
Book at
hos.tdstickets.com
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Kansas City, Mo to St Louis, Mo
Ave. Duration
4 h
Frequency
Hourly
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Bus from St Louis, Mo to Champaign, Il
Ave. Duration
3 h
Frequency
Hourly
Estimated price
$23 - $55
Website
greyhound.com
Economy
$23 - $35
Flexible
$40 - $55
Bus from Kansas City, Mo to Terre Haute, In
Ave. Duration
9 h 50 min
Frequency
Every 4 hours
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110
Burlington Trailways
Website
burlingtontrailways.com
Bus from Champaign, IL to Indianapolis, IN
Ave. Duration
2 h 20 min
Frequency
3 times a day
Estimated price
$30 - $50
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Galesburg Amtrak to Indianapolis, IN
Ave. Duration
5 h 45 min
Frequency
Every 4 hours
Estimated price
$45 - $80
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Bus from Champaign-Urbana to Indianapolis
Ave. Duration
3 h 10 min
Frequency
Twice daily
Website
amtrak.com
Bus from Galesburg to Indianapolis
Ave. Duration
6 h 10 min
Frequency
Twice daily
Website
amtrak.com

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