There are 9 ways to get from Missouri to Chicago by plane, train (Amtrak), bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Columbia Regional Airport to Chicago O'Hare International Airport
best- Fly from Columbia Regional Airport (COU) to Chicago O'Hare International Airport (ORD)COU - ORD
2h 31m$92–320Train (Amtrak)
cheapest- Take the train from Kansas City to Chicago Union StationSouthwest Chief / ...
8h 47m$65–190Bus
- Take the bus from Kansas City to Des MoinesJefferson 802 / ...
- Take the bus from Des Moines to Chicago Bus StationGreyhound US0123 / ...
11h 5m$73–187Drive 502.7 mi
- Drive from Kansas City to Chicago502.7 mi
8h 38m$92–133Fly Springfield-Branson National Airport to Chicago O'Hare International Airport
- Fly from Springfield-Branson National Airport (SGF) to Chicago O'Hare International Airport (ORD)SGF - ORD
2h 41m$73–374Fly Lambert–St. Louis International Airport to Chicago Midway International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)STL - MDW
3h 17m$74–478Fly Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)STL - ORD
3h 44m$184–498Fly Kansas City to Chicago Midway International Airport
- Fly from Kansas City (MCI) to Chicago Midway International Airport (MDW)MCI - MDW
3h 53m$77–465Fly Kansas City to Chicago O'Hare International Airport
- Fly from Kansas City (MCI) to Chicago O'Hare International Airport (ORD)MCI - ORD
4h 23m$142–655
Missouri to Chicago by tram and train (Amtrak)
Questions & Answers
The cheapest way to get from Missouri to Chicago is to drive which costs $90 - $140 and takes 8h 38m.
The fastest way to get from Missouri to Chicago is to fly which takes 2h 31m and costs $90 - $320.
No, there is no direct bus from Missouri to Chicago station. However, there are services departing from Kansas City and arriving at Chicago Bus Station via Des Moines. The journey, including transfers, takes approximately 11h 5m.
No, there is no direct train from Missouri to Chicago station. However, there are services departing from Metro Center and arriving at Chicago Union Station via Kansas City. The journey, including transfers, takes approximately 8h 47m.
The distance between Missouri and Chicago is 348 miles. The road distance is 505.7 miles.
The best way to get from Missouri to Chicago without a car is to train which takes 8h 47m and costs $65 - $190.
It takes approximately 2h 31m to get from Missouri to Chicago, including transfers.
Missouri to Chicago bus services, operated by Jefferson Lines, depart from Kansas City station.
Missouri to Chicago train services, operated by Amtrak, depart from Kansas City station.
The best way to get from Missouri to Chicago is to fly which takes 2h 31m and costs $90 - $320. Alternatively, you can train, which costs $65 - $190 and takes 8h 47m, you could also bus, which costs $70 - $190 and takes 11h 5m.
What companies run services between Missouri, USA and Chicago, IL, USA?
American Airlines and United Airlines fly from Columbia Regional Airport (COU) to Chicago O'Hare International Airport (ORD) every 4 hours. Alternatively, Amtrak operates a train from Kansas City to Chicago Union Station twice daily. Tickets cost $65–190 and the journey takes 7h 41m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 9m
- When
- Every day
- Estimated price
- $70–470
Flights from Kansas City to Chicago Midway International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $75–460
Flights from Kansas City to Chicago Midway International Airport via Lambert–St. Louis International Airport
- Ave. Duration
- 3h 12m
- When
- Thursday and Saturday
- Estimated price
- $80–480
- Website
- aa.com
Flights from Columbia Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $35–250
Flights from Springfield-Branson National Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $55–350
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $50–360
Flights from Kansas City to Chicago O'Hare International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $55–350
- Website
- united.com
Flights from Columbia Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $35–250
Flights from Springfield-Branson National Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $55–350
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $50–360
Flights from Kansas City to Chicago O'Hare International Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $55–350
- Website
- gojetairlines.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $50–360
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Kansas City to Chicago Union Station
- Ave. Duration
- 7h 41m
- Frequency
- Twice daily
- Estimated price
- $65–190
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Kansas City to Des Moines
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 5 times a day
- Estimated price
- $55–100
- Website
- https://www.greyhound.com/
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More Questions & Answers
Missouri to Chicago bus services, operated by Jefferson Lines, arrive at Des Moines station.
Missouri to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Missouri to Chicago is 506 miles. It takes approximately 8h 38m to drive from Missouri to Chicago.
There are 1237+ hotels available in Chicago.