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How to get fromMissouri to Buffaloby plane, train (Amtrak), bus (Greyhound), car or bus

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There are 6 ways to get from Missouri to Buffalo by plane, train (Amtrak), bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lambert–St. Louis International Airport to Buffalo Niagara International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF)plane plane STL - BUF
    5h 55m
    $264–1,504

  2. Bus

    cheapest
    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Columbusbus bus
    3. Take the bus from Columbus - Mound St to Buffalo, NYbus bus
    22h 55m
    $147–296

  3. Train (Amtrak)

    1. Take the train from Kansas City to Chicago Union Stationtrain train Southwest Chief / ...
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    20h 46m
    $246–548

  4. Drive 976.7 mi

    1. Drive from Kansas City to Buffalocar car 976.7 mi
    16h 43m
    $179–258

  5. Fly Kansas City to Buffalo Niagara International Airport

    1. Fly from Kansas City (MCI) to Buffalo Niagara International Airport (BUF)plane plane MCI - BUF
    6h 46m
    $272–1,502

  6. Fly Lambert–St. Louis International Airport to Rochester, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Rochester (ROC)plane plane STL - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 41m
    $178–898

Missouri to Buffalo by train and bus (Amtrak)

Calendar14Weekly Services
Duration20h 46mAverage Duration
Ticket$246Cheapest Price
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Questions & Answers

What companies run services between Missouri, USA and Buffalo, NY, USA?

Southwest Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a train from Kansas City to Court Street & Pearl Street via Chicago Union Station, Buffalo Depew Station, Dick Road & AMTRAK Station, and Walden Avenue & Thruway Transit Center in around 20h 46m.

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