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How to get fromMissouri to Buffaloby plane, train (Amtrak), bus (Greyhound), car, bus or shuttle

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There are 7 ways to get from Missouri to Buffalo by plane, train (Amtrak), bus (Greyhound), car, bus, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lambert–St. Louis International Airport to Buffalo Niagara International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF)plane plane STL - BUF
    6h 31m
    $306–1,782

  2. Train (Amtrak)

    cheapest
    1. Take the train from Kansas City to Chicago Union Stationtrain train Southwest Chief / ...
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    21h 31m
    $132–470

  3. Bus

    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Columbusbus bus
    3. Take the bus from Columbus - Mound St to Buffalo, NYbus bus
    22h 55m
    $137–239

  4. Drive 976.7 mi

    1. Drive from Kansas City to Buffalocar car 976.7 mi
    16h 30m
    $179–258

  5. Fly Kansas City to Buffalo Niagara International Airport

    1. Fly from Kansas City (MCI) to Buffalo Niagara International Airport (BUF)plane plane MCI - BUF
    7h 17m
    $314–1,680

  6. Fly Lambert–St. Louis International Airport to Rochester, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Rochester (ROC)plane plane STL - ROC
    2. Take the bus from Rochester, NY to Buffalo, NYbus bus
    8h 42m
    $186–1,038

  7. Fly Lambert–St. Louis International Airport to Toronto Pearson International Airport, shuttle

    1. Fly from Lambert–St. Louis International Airport (STL) to Toronto Pearson International Airport (YYZ)plane plane STL - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    8h 17m
    $346–952

Missouri to Buffalo by tram and train (Amtrak)

Calendar14Weekly Services
Duration21h 31mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

What companies run services between Missouri, USA and Buffalo, NY, USA?

Southwest Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a vehicle from Metro Center to Buffalo via Union Station, Kansas City, Chicago Union Station, and Buffalo Depew Station in around 21h 31m.

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Need to know: Greyhound

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