Rome2Rio

How to get fromMissouri to BuffaloBy plane, bus (Greyhound), train (Amtrak), car, shuttle, or bus

Find Transport to Buffalo

See all options

There are 7 ways to get from Missouri to Buffalo by plane, bus (Greyhound), train (Amtrak), car, shuttle, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lambert–St. Louis International Airport to Buffalo Niagara International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF)plane plane STL - BUF
    6h 8m
    $218–1,230

  2. Bus

    cheapest
    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis, IN to Toledobus bus
    4. Take the bus from Toledo to Clevelandbus bus
    5. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    21h 15m
    $125–315

  3. Train (Amtrak)

    1. Take the train from Kansas City to Chicago Union Stationtrain train Southwest Chief / ...
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    21h 31m
    $269–653

  4. Drive 976.7 mi

    1. Drive from Kansas City to Buffalocar car 976.7 mi
    16h 43m
    $179–258

  5. Fly Kansas City to Buffalo Niagara International Airport

    1. Fly from Kansas City (MCI) to Buffalo Niagara International Airport (BUF)plane plane MCI - BUF
    6h 44m
    $245–1,328

  6. Fly Lambert–St. Louis International Airport to Toronto Pearson International Airport, shuttle

    1. Fly from Lambert–St. Louis International Airport (STL) to Toronto Pearson International Airport (YYZ)plane plane STL - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    7h 59m
    $598–1,250

  7. Fly Lambert–St. Louis International Airport to Cleveland-Hopkins International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Cleveland-Hopkins International Airport (CLE)plane plane STL - CLE
    2. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    7h 55m
    $136–768

Missouri to Buffalo by bus

Calendar7Weekly Buses
Duration21h 15mAverage Duration
Ticket$125Cheapest Price
See schedules

Questions & Answers

What companies run services between Missouri, USA and Buffalo, NY, USA?

Southwest Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Kansas City Bus Station to Buffalo, NY via St Louis Bus Station, Indianapolis, IN, Toledo, and Cleveland, OH in around 21h 15m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Where to next?

Trips from Missouri

Trips to Buffalo

Popular routes