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How to get fromMissouri to Buffaloby plane, train, bus, train (Amtrak), car, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Missouri to Buffalo by plane, train, bus, train (Amtrak), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lambert–St. Louis International Airport to Buffalo Niagara International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF)plane plane STL - BUF
    6h 11m
    $118–680

  2. Fly Lambert–St. Louis International Airport to Toronto Pearson International Airport, bus

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Toronto Pearson International Airport (YYZ)plane plane STL - YYZ
    2. Take the bus from Toronto Pearson Airport to Buffalobus bus
    8h 35m
    $86–416

  3. Train, bus

    1. Take the train from Kansas City to Chicago Union Stationtrain train
    2. Take the bus from Chicago to Clevelandbus bus
    3. Take the bus from Cleveland to Buffalobus bus
    21h 1m
    $289–509

  4. Train (Amtrak)

    1. Take the train from Kansas City to Chicago Union Stationtrain train Southwest Chief / ...
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    21h 51m
    $535–823

  5. Drive  976.7 mi

    1. Drive from Kansas City to Buffalocar car 976.7 mi
    16h 40m
    $179–258

  6. Fly Kansas City to Buffalo Niagara International Airport

    1. Fly from Kansas City (MCI) to Buffalo Niagara International Airport (BUF)plane plane MCI - BUF
    7h 2m
    $165–878

  7. Fly Lambert–St. Louis International Airport to Rochester, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Rochester (ROC)plane plane STL - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 50m
    $192–944

  8. Bus

    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Columbusbus bus
    3. Take the bus from Columbus to Buffalobus bus
    23h 34m
    $158–251

Missouri to Buffalo by tram, train, foot, and bus

Calendar7Weekly Services
Duration21h 1mAverage Duration
Ticket$289Cheapest Price
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Comparing Your Travel Options

Map of how to get from Missouri to Buffalo.ExpandLaunch map view
  • Distance: 696.4 mi
  • Duration: 6h 11m

What companies run services between Missouri, USA and Buffalo, NY, USA?

Southwest Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF) every 2 hours. Alternatively, you can take a vehicle from Metro Center to Court Street & Pearl Street via Union Station, Kansas City, Chicago Union Station, Buffalo Depew Station, Dick Road & AMTRAK Station, and Walden Avenue & Thruway Transit Center in around 21h 51m.

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