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How to get fromMississauga to Durhamby plane, bus (Flixbus, Greyhound), train (Amtrak), car, shuttle or bus (Greyhound)

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There are 7 ways to get from Mississauga to Durham by plane, bus (Flixbus, Greyhound), train (Amtrak), car, shuttle, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Toronto Pearson International Airport

    best
    1. Fly from Toronto Pearson International Airport (YYZ) to Raleigh-Durham International Airport (RDU)plane plane YYZ - RDU
    5h 55m
    $154–608

  2. Bus

    cheapest
    1. Take the bus from Mississauga to Newarkbus bus Adt N809
    2. Take the bus from Newark Penn Station to Durhambus bus FlixBus N2471
    24h 23m
    $133–444

  3. Train

    1. Take the train from Oakville to New York Penn Stationtrain train VIA Rail
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Stationtrain train Carolinian
    28h 7m
    $170–346

  4. Drive 662.3 mi

    1. Drive from Mississauga to Durhamcar car 662.3 mi
    14h 8m
    $152–219

  5. Shuttle to Buffalo Niagara International Airport, fly

    1. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Raleigh-Durham International Airport (RDU)plane plane BUF - RDU
    7h 7m
    $214–878

  6. Fly from Toronto Island Airport

    1. Fly from Toronto Island Airport (YTZ) to Raleigh-Durham International Airport (RDU)plane plane YTZ - RDU
    8h 48m
    $209–624

  7. Bus via Union Station Bus Terminal (Greyhound)

    1. Take the bus from Toronto to Port Authority Bus Terminalbus bus Greyhound US0215
    2. Take the bus from Port Authority Bus Terminal to Durhambus bus Greyhound US0670
    27h 29m
    $135–246

Mississauga to Durham by bus

Calendar7Weekly Buses
Duration24h 23mAverage Duration
Ticket$133Cheapest Price
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Questions & Answers

What companies run services between Mississauga, ON, Canada and Durham, NC, USA?

Air Canada, United Airlines, and two other airlines fly from Toronto Pearson International Airport (YYZ) to Raleigh-Durham International Airport (RDU) every 4 hours. Alternatively, you can take a bus from City Centre Transit Terminal Platform O to Durham via Mississauga and Newark Penn Station in around 24h 23m.

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