Rome2Rio

How to get fromMississauga to Bostonby bus (Greyhound), train (Amtrak), car, plane, train, bus (Flixbus), or ferry

Find Transport to Boston

See all options

There are 7 ways to get from Mississauga to Boston by bus (Greyhound), train (Amtrak), car, plane, train, bus (Flixbus), or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Mississauga to Buffalobus bus Adt N809-D / ...
    2. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    15h 3m
    $103–189

  2. Train

    1. Take the train from Toronto Union Station to Buffalotrain train VIA Rail
    2. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    18h 11m
    $295–606

  3. Drive  533.6 mi

    1. Drive from Mississauga to Bostoncar car 533.6 mi
    9h 28m
    $123–177

  4. Fly Toronto Island Airport to Laguardia Airport, train

    1. Fly from Toronto Island Airport (YTZ) to Laguardia Airport (LGA)plane plane YTZ - LGA
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    9h 43m
    $778–1,612

  5. Bus via Ithaca (Flixbus)

    1. Take the bus from Toronto to Ithacabus bus FlixBus 2685 / ...
    2. Take the bus from Ithaca to Bostonbus bus FlixBus 2691
    18h 14m
    $104–160

  6. Fly Toronto Pearson International Airport to Provincetown Municipal Airport, ferry

    1. Fly from Toronto Pearson International Airport (YYZ) to Provincetown Municipal Airport (PVC)plane plane YYZ - PVC
    2. Take the ferry from MacMillan Pier, Provincetown, MA to World Trade Center Pier, Boston, MAferry ferry
    9h 13m
    $150–494

  7. Fly Toronto Island Airport to Provincetown Municipal Airport, ferry

    1. Fly from Toronto Island Airport (YTZ) to Provincetown Municipal Airport (PVC)plane plane YTZ - PVC
    2. Take the ferry from MacMillan Pier, Provincetown, MA to World Trade Center Pier, Boston, MAferry ferry
    8h 57m
    $156–516

Mississauga to Boston by bus

Calendar7Weekly Buses
Duration15h 3mAverage Duration
Ticket$103Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Mississauga to Boston.ExpandLaunch map view
  • Distance: 559.7 mi
  • Duration: 15h 3m

What companies run services between Mississauga, ON, Canada and Boston, MA, USA?

You can take a bus from City Centre Transit Terminal Platform O to Boston via Mississauga and Buffalo in around 15h 3m. Alternatively, you can take a train from Erindale GO to Boston via Toronto Union Station and Buffalo Depew Station in around 18h 11m.

Airlines
Train operators
Bus operators
Ferry operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There